Antial is an antihistamine medication that is typically used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itching of the throat or nose. It is generally considered safe and well-tolerated, but like all medications, Antial can have side effects. Here are some common and less common side effects associated with Antial.

Common Side Effects

  • Drowsiness: Antial is considered a non-sedating antihistamine, which means it is less likely to cause drowsiness compared to older antihistamines. However, some people may still experience mild drowsiness, especially when they first start taking it.
  • Dry Mouth: A dry or parched feeling in the mouth is a relatively common side effect of Antial.
  • Headache: Some individuals may experience mild headaches while taking Antial.
  • Stomach Upset: Nausea or an upset stomach can occur in a small percentage of people.

Less Common Side Effects

  • Nervousness or Agitation: In rare cases, Antial may cause restlessness or nervousness.
  • Rapid Heartbeat (Tachycardia): While uncommon, some individuals may experience a rapid or irregular heartbeat with Antial.
  • Allergic Reactions: Although rare, allergic reactions to Antial can occur. Signs of an allergic reaction may include hives, itching, swelling, severe dizziness, and difficulty breathing.
  • Liver Problems: Extremely rare cases of liver problems associated with Antial have been reported, but a direct link has not been conclusively established.
  • Difficulty Urinating: Antial can sometimes cause difficulty in passing urine, particularly in individuals with preexisting urinary conditions.
  • Skin Rash: In rare instances, Antial may cause skin rashes.
Antial Side Effects

What is Antial?

Antial is one of the leading brands of Loratadine, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd.

DASH : Available Formulations and Strengths

Presently, Antial is available in Tablet and Syrup Forms.

Antial Tablets : 10mg strength

Antial Syrup : 5mg/5ml strength

What Are The Possible Drug Interactions of Antial?

  1. Central Nervous System Depressants: Combining Antial with other central nervous system depressants, such as sedatives, tranquilizers, or alcohol, may enhance the sedative effects of Antial and increase drowsiness. It’s advisable to avoid or use caution when combining Antial with these substances, especially if you need to be alert.
  2. Ketoconazole or Erythromycin: These antifungal and antibiotic medications can inhibit the metabolism of Antial in the liver, potentially leading to increased levels of the drug in the bloodstream. This can increase the risk of side effects. Your healthcare provider may recommend adjusting the Antial dosage if you need to take these medications concurrently.
  3. Cimetidine: Cimetidine (medication for heartburn and ulcers) can interfere with the metabolism of Antial leading to higher levels of the drug in the blood. Your healthcare provider may need to adjust the dosage.
  4. Theophylline: Theophylline (medication for respiratory conditions) may have its effects enhanced when taken with Antial. Your healthcare provider may need to monitor theophylline levels and adjust the dosage as necessary.
  5. Other Antihistamines: Combining Antial with other antihistamines may lead to excessive antihistamine effects and increased drowsiness. It’s generally not recommended to take multiple antihistamines simultaneously.
  6. Other Medications Metabolized in the Liver: Antial is primarily metabolized in the liver and medications that affect liver enzymes may interact with Antial. Before combining Antial with such drugs consult with your healthcare provider to determine potential interactions.
  7. Grapefruit Juice: Grapefruit juice can inhibit the enzymes responsible for metabolizing Antial, potentially increasing its levels in the bloodstream. It’s advisable to avoid large quantities of grapefruit juice when taking Antial.
  8. Medications That Cause Urinary Retention: Antial can cause urinary retention in some individuals. When taken with medications that can exacerbate this effect, such as anticholinergic drugs, it may lead to more severe urinary issues.