Loprin is primarily used to prevent heart attacks and strokes in people who are at high risk for these events. It is also used to relieve mild to moderate pain, reduce fever, and treat inflammation. Following are some common and off-label uses of Loprin tablets:

Common Uses of Loprin Tablet

  1. Preventing Blood Clots: Using Loprin tablets can help prevent blood clots from forming in the body. It is often used to reduce the risk of heart attack, stroke, and other conditions caused by blood clots.
  2. Pain Relief: Loprin tablet is used to relieve pain caused by headaches, menstrual cramps, toothaches, muscle aches, and other types of pain.
  3. Treating Inflammatory Conditions: Loprin can reduce inflammation and is often used to treat conditions such as rheumatoid arthritis, osteoarthritis, and lupus.
  4. Reducing Fever: Loprin is also used as an antipyretic medication that can help reduce fever.
  5. Preventing Cancer: Long-term use of Loprin 75mg tablets (low dose) may reduce the risk of certain types of cancer, such as colon, breast, and lung cancer.

Off-label Uses of Loprin Tablet

  1. Prevention of Preeclampsia: In certain cases, Loprin 75mg tablet (low-dose) may be recommended to pregnant individuals who are at high risk of developing preeclampsia, a serious condition characterized by high blood pressure and damage to organs.
  2. Treatment of Migraine: In some cases, Loprin tablets may be used as part of a treatment plan for migraines, especially when other medications are not effective.
  3. Polycythemia Vera: Loprin tablets may be considered as part of the treatment plan for individuals with polycythemia vera, a condition characterized by an overproduction of red blood cells.
  4. Alleviation of Acute Coronary Syndrome (ACS): Loprin tablet is a standard treatment for individuals with acute coronary syndrome, which includes unstable angina and myocardial infarction (heart attack).
Loprin Uses and Indications

What is Loprin?

Loprin is one of the leading brands of Aspirin, manufactured and marketed by Highnoon Laboratories Limited Pakistan.

Loprin Alternatives : Other Similar Brands

The following are some alternative brands of Loprin and their manufacturers.

  • Disprin : Reckitt Benckiser (Pvt) Ltd.
  • Ascard : Atco Laboratories, Pakistan.
  • Aspro : Reckitt Benckiser (Pvt) Ltd.
  • Doloprin : Pacific Pharmaceuticals, Pakistan.
  • Aspicot : Scotmann Pharmaceuticals, Pakistan.
  • Aspidis : Zafa Pharmaceuticals, Pakistan.
  • Asrin : Star Laboratories (Pvt) Ltd, Pakistan.
  • Bloprin : Bloom Pharmaceuticals, Pakistan.
  • Caspia : Epla Laboratories, Pakistan.
  • Diprin : Genome Pharmaceuticals, Pakistan.

Loprin : Available Formulations and Strengths

Presently, Loprin is available in Tablet Form

Loprin Tablet : 75mg and 150mg Strengths.

Who Should Not Use Loprin?

Although, Use of Loprin tablets is an effective treatment option still it has been known to carry some contraindications for certain individuals.

Allergy or hypersensitivity to Loprin: Individuals who are allergic to Loprin or other nonsteroidal anti-inflammatory drugs (NSAIDs) should not use Loprin.

Bleeding disorders: Loprin can increase the risk of bleeding, so it should be avoided in people with bleeding disorders, such as hemophilia or von Willebrand disease.

Stomach ulcers or gastrointestinal bleeding: Loprin can irritate the stomach lining and increase the risk of gastrointestinal bleeding, so it should be avoided in people with a history of stomach ulcers or bleeding.

Pregnancy: Loprin should be avoided during pregnancy, particularly in the third trimester, as it can increase the risk of bleeding and cause other complications.

Children under the age of 16: Loprin should not be given to children under the age of 16, as it can lead to a rare but potentially serious condition called Reye’s syndrome.

Asthma: Loprin can trigger asthma attacks in some people with asthma, particularly those with a history of Loprin sensitivity or intolerance.

What is the Recommended Daily Dosage of Loprin Tablet?

The dose of Loprin tablet may vary depending on the purpose for which it is being used.

  • Pain relief: 2-4 tablets of 150mg every 4 to 6 hours.
  • Fever reduction: 2-4 tablets of 150mg every 4 to 6 hours.
  • Blood clot prevention: 1-4 tablets of 75mg per day.
  • Maximum Daily Dose of Loprin: 4gm (4000mg) per day.

To avoid gastrointestinal problems use Loprin tablets after meals (Loprin should not use empty stomach).

How Loprin Works?

Loprin works primarily by blocking enzymes called cyclooxygenases (COX). These enzymes are responsible for producing substances called prostaglandins that are involved in inflammation and pain perception within the body. By blocking these enzymes, Loprin reduces levels of prostaglandins which leads to decreased inflammation and pain relief while reducing the risk of blood clots forming within vessels leading away from the heart and brain (which can cause a stroke or heart attack).

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