Caricef tablet is a broad-spectrum antibiotic that is used to treat various bacterial infections. It belongs to a class of drugs known as cephalosporins. Following are some common and off-label uses of Caricef tablet

Some Common Uses of Caricef Tablet

  1. Respiratory Tract Infections: Caricef tablets can be used to treat infections of the respiratory tract, such as bronchitis, pneumonia, and sinusitis.
  2. Urinary Tract Infections: Caricef tablets can be used to treat urinary tract infections (UTIs) caused by bacteria, including cystitis and pyelonephritis.
  3. Ear Infections: Caricef tablets can be used to treat middle ear infections (otitis media) caused by bacteria.
  4. Gonorrhea: Caricef table is often used to treat gonorrhea, a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae.
  5. Typhoid Fever: Caricef tablets can be used to treat typhoid fever, a bacterial infection that is spread through contaminated food and water.

Off-Label Uses of Caricef Tablet

  1. Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD): Caricef tablets may be used off-label in combination with other medications to treat acute exacerbations of COPD caused by bacterial infections.
  2. Pharyngitis and Tonsillitis: Caricef tablets may be used off-label to treat bacterial infections of the throat, such as pharyngitis and tonsillitis.
  3. Skin and Soft Tissue Infections: Caricef tablets may be used off-label to treat bacterial skin and soft tissue infections, such as cellulitis and impetigo.
  4. Community-Acquired Pneumonia: Caricef tablets may be used off-label in combination with other medications to treat community-acquired pneumonia caused by bacteria.
Caricef Uses and Indications

What is Caricef?

Caricef is one of the leading brands of Cefixime, manufactured and marketed by Sami Pharmaceuticals, Pakistan.

Caricef Alternatives : Other Similar Brands

The following are some available alternative brands of Caricef.

  • Cebosh : Bosch Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Cefiget : Getz Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Cefim : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Cefspan : Barrett Hodgson Pakistan (Pvt) Ltd.
  • Fixitil : Tabros Pharma (Pvt) Ltd, Pakistan.
  • Icef : ICI Pakistan Ltd.
  • Linzim : Bosch Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Magnett : S.J. & G Fazul Ellahie (Pvt) Ltd, Pakistan.
  • Maxima : Macter International (Pvt) Ltd.
  • Maxpan : Indus Pharma (Pvt) Ltd, Pakistan.
  • Mixel : High-Q International.

Caricef : Available Formulations and Strengths

Presently, Caricef is available in Tablets, Capsules, and Syrup forms

Caricef Tablets : 200mg, and 400mg strengths

Caricef Capsules : 400mg strength

Caricef Syrup : 100mg/5ml strength

Caricef DS Syrup : 200mg/5ml strength

Who Should Not Use Caricef?

Caricef is a relatively safe and well-tolerated antibiotic, but there are some contraindications and precautions that should be considered before using Caricef.

Allergy or hypersensitivity to Caricef or other cephalosporin antibiotics: Patients with a history of allergic reactions to Caricef or other cephalosporin antibiotics should not take Caricef as it may cause a severe allergic reaction.

Severe kidney disease: Caricef is primarily eliminated from the body through the kidneys, and patients with severe kidney disease may be at an increased risk of side effects or toxicity.

Gastrointestinal disorders: Individuals with a history of colitis or other gastrointestinal disorders may be at an increased risk of developing antibiotic-associated diarrhea or other gastrointestinal side effects when using Caricef.

Pregnancy and breast-feeding: Caricef should only be used in pregnancy and breastfeeding if the potential benefits outweigh the risks. It is important to discuss the risks and benefits with a healthcare provider before using Caricef.

Infants younger than 6 months: Caricef should not be used in infants younger than 6 months of age as the safety and efficacy of this medication have not been established in this population.

What is the Recommended Daily Dosage of Caricef?

Caricef Dose for Adults & Children (over 12 years): 400mg/day. (At once or in 2 divided doses)

Caricef Dose for Chronic or Resistant Infections: Caricef tablet 400mg as a single dose is recommended.

Caricef Dose for Children: 8mg/kg/day, administered as a single dose.

Caricef Suspension dosage for children is depending on age group also:

1-4 years: 5ml daily

5-9 years: 10ml daily

10-12 years: 15ml daily

Caricef DS Suspension Dosage:

1-4 years: 2.5ml/day

5-9 years: 5ml/day

10-12 years: 7.5ml/day

Children above 12 years: 10ml/day

How Caricef Works?

Caricef contains cefixime which works by stopping the growth of bacteria by binding to PBPs (penicillin-binding proteins). As a result, it inhibits the cell wall synthesis of bacteria.

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