Spasfon tablet is a medication that is primarily used to treat sudden, severe abdomen pain. It is also used for the treatment of renal colic and urinary tract pain and spasms. Spasfon is an antispasmodic drug that helps to reduce spasms in the gastrointestinal tract, bladder, and uterus. Following are some common and off-label uses of the Spasfon tablet:

Common Uses of Spasfon Tablet

  1. Irritable Bowel Syndrome: Spasfon tablet is used to reduce symptoms of irritable bowel syndrome (IBS), such as abdominal pain, bloating, and diarrhea.
  2. Abdominal Pain: Spasfon tablet is used to relieve abdominal pain and discomfort caused by gastrointestinal disorders characterized by spasms of the digestive tract.
  3. Genitourinary Spasms: Spasfon tablets may also be used to relieve spasms in the genitourinary tract, which can occur in conditions like urinary tract infections or kidney stones.
  4. Menstrual Cramps: Spasfon tablets may be used to help alleviate the pain and discomfort associated with menstrual cramps (dysmenorrhea) by relaxing the uterine muscles.
  5. Biliary Disorders: In some cases, Spasfon tablets may be used to alleviate spasms and pain associated with disorders of the biliary tract.
  6. Urological Disorders: Spasfon tablets may be used to relieve spasms and pain in the urinary tract due to conditions like ureteral stones or urinary tract infections.
  7. Gastrointestinal Diagnostic Procedures: Spasfon tablets may be used to relax the digestive tract muscles during certain diagnostic procedures, such as endoscopy or colonoscopy.

Off-label Uses of Spasfon Tablet

  1. Migraine: In some cases, Spasfon tablets may be used off-label to help manage migraines, especially those with a significant smooth muscle component.
  2. Dysfunctional Uterine Bleeding: Spasfon tablets may be considered as part of the treatment plan for dysfunctional uterine bleeding, particularly when uterine muscle spasms contribute to excessive bleeding.
  3. Gallbladder Disorders: In certain situations, Spasfon tablets may be used off-label to help manage spasms and pain associated with disorders of the gallbladder.
  4. Labor Induction and Augmentation: Spasfon tablets may be considered in some cases to help relax uterine muscles during labor induction or augmentation.

In addition, Spasfon tablets also have some anti-cancer properties. It provides powerful antioxidant effects to protect cells from the harmful effects of free radicals, which are unstable molecules and can damage cells and contribute to various diseases including cancer. Spasfon tablets may help inhibit tumor growth and even act as a chemoprotective agent against certain types of cancer cells.

Spasfon Uses and Indications

What is Spasfon?

Spasfon is one of the leading brands of Phloroglucinol Trimethylphloroglucinol, manufactured and marketed by Himont Pharmaceuticals (Pvt), Pakistan.

Spasfon Alternatives : Other Similar Brands

Below are some available similar brands that can be used as an alternative to Spasfon:

  • Spasrid : Barrett Hodgson (Pvt) Ltd, Pakistan.
  • Anafortan Plus : AGP (Pvt) Ltd, Pakistan.
  • Spadix : Tabros Pharmaceuticals, Pakistan.
  • Orglu : Sami Pharmaceuticals, Pakistan.
  • Helispa Plus : Helix Pharmaceuticals, Pakistan.
  • Gluthyl : Mass Pharma (Pvt) Ltd, Pakistan.
  • Furosinol : Century Pharmaceuticals, Pakistan.
  • Spastrim : Medera Pharmaceuticals, Pakistan.
  • Spasmex : Angelini Pharmaceuticals (Pvt) Ltd, Pakistan.

Spasfon : Available Formulations and Strengths

Presently, Spasfon is available in Tablet and Injection forms

Spasfon Tablet : 80mg strength

Spasfon Injection : 40mg/4ml strength

Who Should Not Use Spasfon?

As with any medication, there are certain risks and contraindications associated with the use of Spasfon tablets. It is important for patients to understand the risks and contraindications of this medication before it is prescribed or taken.

  • The use of Spasfon may also not be suitable for some individuals due to certain underlying conditions or other medications they are taking concurrently.
  • Those who have an allergy to any components in Spasfon should avoid using it completely, as this could potentially cause anaphylaxis, which can be fatal if left untreated.
  • Patients with chronic liver disease should also avoid using Spasfon, as its active ingredients can cause further damage to their already weakened livers due to its hepatotoxic nature when taken in large amounts over long periods of time.
  • Pregnant and breastfeeding women should speak to their doctor prior to using Spasfon, as it has not been extensively studied in either group yet and could potentially cause harm if used without proper consultation beforehand.

What is the Recommended Daily Dosage of Spasfon Tablet?

Spasfon Tablet Dose for Irritable Bowel Syndrome (IBS):

  • One tablet of 80mg, Three times a day.

Spasfon Tablet Dose for Functional Gastrointestinal Disorders:

  • One tablet of 80mg, Three times a day.

Spasfon Tablet Dose for Ureteral Colic:

  • One tablet of 80mg, Three times a day.

Spasfon Tablet Dose for Menstrual Cramps:

  • One tablet of 80mg, Three times a day
  • (During the menstrual period to alleviate cramping)

Spasfon Injection:

  • 1 to 3 ampules in 24 hours.
  • Injection can be administered intramuscularly (IM) or intravenously (IV).

How Spasfon Works?

Spasfon works directly on the smooth muscle and creates muscle relaxation by inhibiting voltage-gated calcium channels without having anticholinergic side effects associated with the other classes of antispasmodics.

In addition, Spasfon inhibits the action of Catechol-O-Methyl Transferase (COMT) Resultantly, it decreases the intensity of the spasms.

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Spasfon Side Effects