Sensival tablet is a medication primarily used for treating depression. It belongs to a class of drugs called tricyclic antidepressants (TCAs). Its main function is to increase the levels of certain brain chemicals (neurotransmitters) called serotonin and norepinephrine, which are thought to play a role in mood regulation. Following are some approved and off-label uses of Sensival Tablets:

Approved Uses of Sensival Tablet

  1. Major Depressive Disorder (MDD): This is the most common use of Sensival tablet, and it is effective in reducing symptoms such as sadness, hopelessness, low energy, changes in appetite or sleep, and difficulty concentrating.
  2. Panic Disorder: Sensival tablets can sometimes be used as part of a treatment plan for panic disorder, a type of anxiety disorder characterized by sudden episodes of intense fear.

Off-label Uses of Sensival Tablet

  1. Chronic Pain: Although not officially approved, Sensival tablet may be used off-label to manage certain chronic pain conditions, such as:
    1. Neuropathic pain: This includes pain caused by nerve damage from conditions like shingles, diabetes, or spinal cord injuries.
    2. Fibromyalgia: A chronic condition characterized by widespread pain and tenderness.
    3. Tension headaches and migraines: Some studies suggest Sensival tablet might be helpful in preventing or reducing the frequency and severity of headaches.
  2. Attention Deficit Hyperactivity Disorder (ADHD): While not a first-line treatment, Sensival tablet may be used off-label in some cases for ADHD, particularly when symptoms involve emotional dysregulation.
  3. Insomnia / Sleep Disorders: Sensival tablet is also for certain sleep disorders, such as insomnia. It can help improve sleep quality and reduce awakenings during the night.
Sensival Uses and Indications

What is Sensival?

Sensival is one of the leading brands of Nortriptyline, manufactured and marketed by Pharmedic (Pvt) Ltd, Pakistan.

Sensival Alternatives : Other Similar Brands

Below are some available similar brands that can be used as an alternative to Sensival:

  • Motival : GlaxoSmithKline Pakistan.
  • Modrin : Pharmedic (Pvt) Ltd, Pakistan.
  • Motisone : Geofman Pharmaceuticals, Pakistan.
  • Notrilin : Usawa Pharmaceuticals, Pakistan.

Sensival : Available Formulations and Strengths

Presently, Sensival is available in Tablets Form.

Sensival Tablets : 25mg and 75mg strengths.

Who Should Not Use Sensival?

Although, Sensival is an effective medication, still has some contraindications.

Hypersensitivity: Sensival should not be used in people who are hypersensitive to the medication or to any of its components.

Recent Myocardial Infarction (Heart Attack): Sensival should not be used in people who have had a recent heart attack.

Arrhythmias: Sensival can cause changes in heart rhythm, so it should not be used in people with certain types of arrhythmias.

Glaucoma: Sensival can increase intraocular pressure, so it should not be used in people with narrow-angle glaucoma.

Urinary Retention: Sensival can cause urinary retention, so it should not be used in people with a history of urinary retention.

MAOI Use: Sensival should not be used in people who are currently taking or have recently taken a monoamine oxidase inhibitor (MAOI).

Seizure Disorders: Sensival can lower the seizure threshold, so it should not be used in people with a history of seizure disorders.

What is the Recommended Daily Dosage of Sensival?

Sensival Dose for Adults with Depression: one tablet once or twice a day, ideally taken at bedtime. The dose may be increased gradually by one tablet 3 times a day.

Sensival Dose for Neuropathic Pain: One tablet per day, taken at bedtime. The dose may be increased gradually by one tablet 3 times a day.

How Sensival Works?

Sensival is a tricyclic antidepressant (TCA) medication that works by increasing the levels of certain chemicals in the brain, specifically norepinephrine and serotonin.

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Sensival Side Effects