Sulvorid tablet is a medication that affects the nervous system and is used to treat various conditions related to gastrointestinal and psychiatric disorders. Sulvorid tablets are commonly used for the following indications:

Sulvorid Tablet’s Uses in Gastrointestinal Issues

Sulvorid tablet has motility regulation effects, it can be used to treat several gastrointestinal issues, including:

  1. Functional Dyspepsia: Sulvorid tablet is used in the treatment of functional dyspepsia, a condition characterized by chronic or recurrent pain or discomfort centered in the upper abdomen. It can help alleviate symptoms like bloating, early satiety, and discomfort.
  2. Gastroesophageal Reflux Disease (GERD): Sulvorid tablets can be used to manage symptoms of GERD, a condition where stomach acid frequently flows back into the esophagus, causing heartburn and discomfort.
  3. Gastroparesis: Sulvorid tablets may be used in the management of gastroparesis, a condition characterized by delayed emptying of the stomach. This leads to symptoms like nausea, vomiting, and bloating.
  4. Irritable Bowel Syndrome (IBS): Sulvorid tablets may be used as part of a treatment plan for individuals with IBS, particularly those with predominant symptoms of bloating and discomfort.
  5. Non-ulcer Dyspepsia: Sulvorid tablets can be used in the treatment of non-ulcer dyspepsia, which involves symptoms like pain and discomfort in the upper abdomen in the absence of any visible ulcer.
  6. Prevention of Nausea and Vomiting: In some cases, Sulvorid tablets may be used to help prevent nausea and vomiting, particularly in individuals with functional gastrointestinal disorders.

Sulvorid Tablet’s Uses in Psychiatric Disorders

  1. Schizophrenia: Sulvorid tablets may be used as an adjunctive treatment for schizophrenia, a mental disorder characterized by disruptions in thought processes, perceptions, and emotions.
  2. Depressive Disorders: Sulvorid tablets can be used in the treatment of depressive disorders, particularly when there are features of anxiety or agitation. It may help alleviate symptoms such as low mood, loss of interest, and disturbances in thought processes.
  3. Bipolar Disorder: Sulvorid tablets may be considered as part of a treatment regimen for bipolar disorder, particularly in managing certain symptoms like agitation or anxiety.
  4. Anxiety Disorders: In some cases, Sulvorid tablets may be used as an adjunctive treatment in certain anxiety disorders, helping to alleviate symptoms of anxiety and restlessness.
Sulvorid Uses and Indications

What is Sulvorid?

Sulvorid is one of the leading brands of Levosulpride, manufactured and marketed by High-Q Pharmaceuticals. Pakistan.

Sulvorid Alternatives : Other Similar Brands

Following are some alternative brands of Sulvorid and their manufacturers.

  • Levopraid : Pacific Pharmaceuticals, Pakistan.
  • Scipride : Scilife Pharmaceuticals, Pakistan.
  • Sapride : Standpharm Pakistan (Pvt) Ltd.
  • Neoprad : Mcolson Research Laboratories, Pakistan.
  • Sulprex : Global Pharmaceuticals, Pakistan.
  • Piride : Amarant Pharmaceuticals, Pakistan.
  • Sulvobid : Pharma Health Pakistan (Pvt) Ltd.
  • Lepride : Helix Pharma (Pvt) Ltd.
  • Motrol : Wilshire Laboratories, Pakistan.
  • Sowel : Dyson Research Laboratories, Pakistan.

Sulvorid : Available Formulations and Strengths

Presently, Sulvorid is available in Tablets form

Sulvorid Tablets : 25mg and 50mg strengths

Who Should Not Use Sulvorid?

Sulvorid has certain contraindications, which are specific situations or conditions in which the use of the medication is not recommended due to potential risks or complications.

Hypersensitivity: Sulvorid is contraindicated in individuals who have a known hypersensitivity or allergy to Sulvorid or any of its components. Allergic reactions can range from mild skin reactions to severe systemic reactions and require immediate medical attention.

Prolactin-dependent tumors: Sulvorid is contraindicated in individuals with known or suspected prolactin-dependent tumors, such as prolactinoma or breast cancer. The medication can increase prolactin levels, which may stimulate the growth of these tumors.

Gastrointestinal obstruction: Sulvorid is contraindicated in individuals with mechanical gastrointestinal obstruction, including bowel obstruction. It can exacerbate the condition by increasing the gut motility and worsening the obstruction.

Pheochromocytoma: Sulvorid is contraindicated in individuals with pheochromocytoma, a rare tumor of the adrenal gland that secretes excessive amounts of catecholamines. The medication can stimulate the release of catecholamines, leading to potentially severe hypertension and other complications.

Parkinson’s disease: Sulvorid is contraindicated in individuals with Parkinson’s disease or Parkinsonian symptoms. The medication may worsen motor symptoms and interfere with the effectiveness of Parkinson’s disease medications.

Severe renal or hepatic impairment: Sulvorid should be used with caution in individuals with severe renal impairment or severe hepatic impairment. The medication may require dose adjustments or close monitoring in such cases.

What is the Recommended Daily Dosage of Sulvorid?

Sulvorid Dose for Gastrointestinal Issues:

  • One tablet of 25mg of Sulvorid 3 times a day
  • Sulvorid daily dosage for children (above 14 years of age) is 3 – 5mg/kg of body weight

Sulvorid Dose for Psychiatric Disorders:

  1. Schizophrenia:
    • Starting dose: One tablet of 50mg per day
    • Maintenance dose: 1 to 2 tablets of 50mg per day, but can be adjusted based on individual response and tolerability
    • Some individuals may require higher doses, up to four tablets of 50mg (200mg) per day
  2. Other Psychotic Disorders:
    • The dosage for other psychotic disorders may be similar to that of schizophrenia, starting at one tablet of 50mg per day and adjusted based on individual response and tolerability
  3. Depression and anxiety (adjunctive treatment):
    • The dosage of Sulvorid when used as an adjunctive treatment for depression and anxiety disorders may be lower compared to treating primary psychotic disorders
    • Starting dose: One tablet of 25mg per day
    • Maintenance dose: 1 to 2 tablets of 25mg per day, but can be adjusted as needed.

How Sulvorid Works?

Sulvorid tablet contains Levosulpride which is a selective dopamine receptor antagonist, that works to block the dopamine (D2) receptors located on the presynaptic neuron.

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Sulvorid Side Effects