Antial syrup is an antihistamine medication that is primarily used to relieve symptoms of allergic reactions and hay fever (allergic rhinitis). Antial Syrup formulation is most recommended for children and adults where a low dose of medicine is needed. The following are some common uses and indications of Antial Syrup:

  1. Allergic Rhinitis: Antial syrup is frequently used to treat allergic rhinitis, which is characterized by symptoms such as sneezing, runny or stuffy nose, itchy or watery eyes, and itching in the throat or nose. It helps alleviate these symptoms by reducing the body’s histamine response to allergens.
  2. Seasonal Allergies: Antial syrup is effective in managing symptoms of seasonal allergies that occur during specific times of the year, such as when pollen levels are high.
  3. Perennial Allergic Rhinitis: This refers to year-round allergic rhinitis caused by allergens like dust mites, pet dander, or mold spores. Antial syrup can provide relief from these symptoms.
  4. Chronic Urticaria (Hives): Antial syrup is also used to relieve itching and reduce the appearance of hives, which are raised, red, itchy bumps on the skin caused by an allergic reaction.
  5. Itchy Skin Conditions: In some cases, Antial syrup may be used to alleviate itching associated with other skin conditions, such as eczema or insect bites.
  6. Allergic Conjunctivitis: Antial can help manage symptoms of allergic conjunctivitis, including itchy, red, and watery eyes.

Off-label Uses of Antial Syrup

  1. Chronic Idiopathic Urticaria: While Antial syrup is commonly used to relieve acute episodes of hives (urticaria), it might be used off-label for chronic idiopathic urticaria, which involves persistent or recurrent hives without an identifiable cause.
  2. Allergic Asthma: Some individuals with allergic asthma may experience relief from symptoms such as coughing and wheezing with the use of antihistamines like Antial syrup, especially when allergies trigger their asthma symptoms.
  3. Eczema (Atopic Dermatitis): Antial syrup might be used to help manage itching associated with eczema, a chronic inflammatory skin condition. It can help alleviate the allergic component of eczema symptoms.
  4. Allergic Reactions to Insect Stings/Bites: Antial syrup could be used to help manage itching and swelling caused by allergic reactions to insect stings or bites.
  5. Allergic Reactions to Medications: In some cases, Antial syrup might be used as part of a treatment plan to manage mild allergic reactions to certain medications.
  6. Chronic Allergic Rhinitis: While Antial syrup is typically recommended for acute allergic rhinitis, it might be considered for longer-term use in individuals with chronic allergic rhinitis.
  7. Prevention of Allergic Reactions: In situations where exposure to allergens is expected, such as before certain outdoor activities, Antial syrup could potentially be used as a preventive measure to reduce the risk of allergic reactions.
Antial Syrup Uses and Indications

What is Antial?

Antial syrup is one of the leading brands of Loratadine, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd.

Antial Alternatives : Loratadine Other Brands

The following are some alternative brands of Antial syrup and their manufacturers.

  • Lorin NSA : Asian Continental Pharma, Pakistan.
  • Xylor : Atco Laboratories, Pakistan.
  • Softin : Werrick Pharmaceuticals, Pakistan.
  • Antimin : Shaigan Pharmaceuticals, Pakistan.
  • Lorel : Standpharm Pakistan.
  • Victrin : Barett Hodgson Pakistan, (Pvt) Ltd.
  • Lorid : Stanly Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Lorate : Pharmix Laboratories (Pvt) Ltd, Pakistan.
  • Allerwood : W. Woodward Pakistan (Pvt) Ltd.
  • Jade : Scotmann Pharmaceuticals, Pakistan.

Antial : Available Formulations and Strengths

Presently, Antial is available in Syrup and Tablet forms.

Antial Syrup : 5mg/5ml strength.

Antial Tablet : 10mg strength.

Who Should Not Use Antial?

Antial syrup is generally considered safe and well-tolerated for most individuals. However, there are certain situations and conditions where its use may be contraindicated or should be approached with caution.

  1. Hypersensitivity or Allergy: Individuals who have a known hypersensitivity or allergy to Loratadine should avoid using Antial syrup.
  2. End-Stage Kidney Disease: Antial syrup is primarily eliminated from the body through the kidneys. Individuals with severe kidney impairment or end-stage kidney disease should use Antial syrup with caution and under the guidance of a healthcare provider, as dosing adjustments may be necessary.
  3. Liver Impairment: Antial syrup is metabolized by the liver. While it is generally considered safe for individuals with mild to moderate liver impairment, caution is advised in cases of severe liver disease. A healthcare provider should be consulted for appropriate dosing guidance.
  4. Pregnancy and Breastfeeding: While Antial syrup is typically considered safe for use during pregnancy and breastfeeding, it’s recommended to consult a healthcare provider before using any medication during these periods.
  5. Elderly Individuals: Older adults may be more susceptible to the potential side effects of Antial syrup, such as drowsiness. Lower doses or careful monitoring may be needed.
  6. Central Nervous System Depressants: Antial syrup may have mild sedative effects, especially when used in higher doses. Caution is advised when using Antial syrup concurrently with other medications or substances that can cause central nervous system depression, such as alcohol, sedatives, or tranquilizers.
  7. Medical Conditions: Individuals with certain medical conditions, such as epilepsy or seizure disorders, should use Antial syrup with caution and under the guidance of a healthcare provider.
  8. Other Medications: Antial syrup may interact with certain medications, including those that affect liver enzymes or cause sedation. It’s important to inform your healthcare provider of all medications you are taking, including over-the-counter drugs, supplements, and herbal products.

Recommended Daily Dosage of Antial Syrup

Antial Syrup Dose for Adults and Children 12 Years and Older:

  • 10 mg (2 teaspoons) once daily.

Antial Syrup Dose for Children 2 to 12 Years Old:

  • The recommended dose may vary based on the child’s weight and the specific product concentration.
  • The usual dose is typically around 5 mg (one teaspoon) once daily.

Antial Syrup Dose for Children Under 2 Years Old:

  • Antial syrup is generally not recommended for children under 2 years of age.
  • Consult a healthcare provider for appropriate alternatives.

How Antial Works?

Antial is an H1 receptor antagonist, which means it competes with histamine for binding to the H1 receptors in cells. By binding to these receptors without activating them, Antial prevents histamine from attaching to the receptors. This action blocks the effects of histamine and helps reduce or alleviate allergy symptoms.

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Antial Side Effects