Sambro is a medication used to treat anxiety and its related conditions. Like all medications, Sambro has both common and less common side effects.

Common Side Effects

  • Drowsiness or sedation: Many people experience drowsiness when taking Sambro, which can impair their ability to drive or operate heavy machinery.
  • Dizziness: Feeling lightheaded or dizzy is a common side effect of Sambro.
  • Muscle weakness: Sambro can cause muscle weakness, making physical activities more challenging.
  • Reduced alertness: You may feel less alert or mentally slowed down when taking Sambro.
  • Cognitive impairment: Some people may experience difficulty with memory, concentration, or coordination while using Sambro.
  • Gastrointestinal disturbances: This can include nausea, vomiting, constipation, or diarrhea.

Less Common Side Effects

  • Headache: Some individuals may experience headaches while taking Sambro.
  • Blurred vision: Sambro causes vision problems, including blurred vision, which can occur in less common cases.
  • Changes in appetite: An increase or decrease in appetite may occur with Sambro.
  • Skin reactions: Skin rashes, itching, or hives may develop in some people.
  • Changes in libido: Sambro can affect sexual desire and function in some individuals.
  • Depression: In some cases, Sambro may paradoxically worsen symptoms of depression or anxiety.
  • Allergic reactions: Although rare, severe allergic reactions can occur with Sambro, leading to symptoms such as swelling of the face, tongue, or throat, difficulty breathing, and skin rash.
  • Changes in blood cell count: Sambro can rarely affect blood cell counts, leading to conditions like agranulocytosis or leukopenia.
  • Dependence and withdrawal: Prolonged use of Sambro can lead to physical and psychological dependence, and withdrawal symptoms may occur if the medication is stopped abruptly.
Sambro Side Effects

What is Sambro?

Sambro is one of the leading brands of Bromazepam, manufactured and marketed by Sami Pharmaceuticals Pakistan.

Sambro : Available Formulations and Strengths

Presently, Sambro is available in Tablets Form

Sambro Tablets : 3mg Strength

What Are The Possible Drug Interactions of Sambro?

  1. Alcohol: Combining Sambro with alcohol can increase sedation and the risk of respiratory depression. It is strongly advised to avoid alcohol while taking Sambro.
  2. Other Benzodiazepines: Concurrent use of multiple benzodiazepines can lead to an increased risk of side effects and addiction. Combining Sambro with other benzodiazepines should be done with caution and under medical supervision.
  3. Opioid Pain Medications: Combining Sambro with opioids such as oxycodone, hydrocodone, or morphine can lead to extreme sedation, respiratory depression, and an increased risk of overdose. This combination should be avoided, and it’s crucial to inform your healthcare provider if you are prescribed both types of medications.
  4. Antidepressants: Some antidepressants, especially selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), can interact with Sambro, potentially increasing the risk of side effects. Your healthcare provider should closely monitor your progress if these medications are used together.
  5. Antipsychotic Medications: Combining Sambro with antipsychotic medications can increase sedation and the risk of side effects. This combination should be used cautiously under medical supervision.
  6. Antihistamines: Over-the-counter and prescription antihistamines (used for allergies and sleep) can enhance the sedative effects of Sambro.
  7. Muscle Relaxants: Combining Sambro with muscle relaxants can increase the risk of sedation and muscle weakness.
  8. Certain Antibiotics: Some antibiotics, particularly erythromycin and clarithromycin, can increase the blood levels of Sambro, potentially leading to stronger sedative effects.
  9. Grapefruit and Grapefruit Juice: Grapefruit and grapefruit juice can interact with Sambro, increasing its concentration in the blood. This can lead to stronger and potentially harmful effects. It’s advisable to avoid grapefruit products while taking Sambro.
  10. CYP3A4 Inhibitors: Drugs that inhibit the activity of the CYP3A4 enzyme in the liver can increase Sambro levels in the blood. This includes certain antifungal medications, such as ketoconazole and itraconazole, and protease inhibitors used in the treatment of HIV.