Orglu is commonly used for its antispasmodic effects on the digestive system, particularly for conditions like irritable bowel syndrome (IBS) and other gastrointestinal spasmodic disorders. While Orglu is generally well-tolerated, it can still cause some common and less common side effects, including:

Common Side Effects

  • Gastrointestinal Disturbances: Nausea, vomiting, diarrhea, or abdominal discomfort are among the most commonly reported side effects of Orglu. However, these symptoms are usually mild and tend to subside with continued use.
  • Allergic Reactions: Some individuals may experience allergic reactions while taking Orglu, which could manifest as skin rashes, itching, swelling (especially of the face, lips, or throat), or hives.
  • Dizziness or Headache: A few people may experience mild dizziness or headaches while taking Orglu.
  • Taste Disturbances: An altered taste sensation, such as a metallic taste in the mouth, is reported by some individuals as a side effect of Orglu.
  • Urinary Tract Symptoms: Infrequent reports associated with Orglu, include urinary retention or difficulty urinating.
  • Cardiovascular Effects: In rare cases, there may be reports of palpitations or changes in heart rate, although these occurrences are uncommon.

Less Common Side Effects

  • Hypersensitivity Reactions: While less common, severe allergic reactions can occur while taking Orglu, leading to symptoms like severe skin rashes, blistering, swelling of the face, tongue, or throat (angioedema), and difficulty breathing. These require immediate medical attention.
  • Liver or Kidney Effects: In rare instances, Orglu might cause abnormalities in liver function tests or kidney function. This could manifest as jaundice (yellowing of the skin or eyes), dark urine, abdominal pain, or changes in urination patterns.
  • Neurological Symptoms: Some individuals might experience neurological side effects of Orglu such as confusion, drowsiness, or tremors. These occurrences are infrequent but should be reported to a healthcare professional if experienced.
  • Hematological Effects: Rarely, there might be alterations in blood cell counts, leading to conditions like anemia, leukopenia (reduced white blood cells), or thrombocytopenia (reduced platelets). This could result in symptoms like fatigue, increased susceptibility to infections, or easy bruising and bleeding.
  • Cardiovascular Effects: Infrequent reports exist of changes in blood pressure or heart rhythm disturbances while taking Orglu.
  • Respiratory Reactions: In rare instances, there could be respiratory symptoms like shortness of breath or difficulty breathing.
Orglu Side Effects

What is Orglu?

Orglu is one of the leading brands with a combination of Phloroglucinol and Trimethylphloroglucinol, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

Orglu : Available Formulations and Strengths

Presently, Orglu is available in Tablet Form with the following Strengths.

Orglu Tablet : Phloroglucinol 80mg and Trimethylphloroglucinol 80mg strengths.

What Are The Possible Drug Interactions of Orglu?

  1. Other Antispasmodic Medications: Combining Orglu with other antispasmodic drugs might lead to additive effects. While this doesn’t necessarily result in severe interactions, it could increase the likelihood of side effects associated with antispasmodics, such as dizziness or gastrointestinal disturbances.
  2. Alcohol: While specific interactions are not well-documented, alcohol might exacerbate the central nervous system depressant effects of Orglu. It could potentially increase dizziness or drowsiness. It’s advisable to use caution or avoid alcohol while taking Orglu.
  3. Medications Affecting the Central Nervous System: Drugs that have sedative or central nervous system depressant effects might potentially interact with Orglu, possibly increasing the risk of drowsiness or dizziness when taken concurrently.
  4. Medications with Anticholinergic Effects: Other medications with anticholinergic properties (such as some antidepressants, antihistamines, or medications for overactive bladder) might theoretically interact with Orglu, possibly leading to additive effects on the gastrointestinal tract or increased risk of anticholinergic side effects.
  5. Other Medications: Always inform your healthcare provider about all medications, supplements, or herbal products you are taking. While no significant interactions are commonly reported, it’s essential to discuss potential interactions with your doctor or pharmacist.