Actifed-P Cold Side Effects

Actifed-P Cold is typically used to relieve symptoms associated with colds, allergies, or sinus congestion. As with any medication, Actifed-P Cold can have side effects, both common and less common.

Common Side Effects

• Drowsiness: Actifed-P Cold can cause drowsiness or sedation in some individuals. It is usually labeled as “non-drowsy” but some people may still experience this side effect. Avoid activities requiring alertness, such as driving or operating heavy machinery, if you feel drowsy.
• Dry Mouth:  Actifed-P Cold can cause dry mouth as a common side effect.
• Nausea or Upset Stomach: Actifed-P Cold can sometimes cause gastrointestinal discomfort, including nausea or an upset stomach.
• Insomnia: In some individuals, Actifed-P Cold can cause difficulty falling asleep or staying asleep.
• Nervousness or Restlessness:  Actifed-P Cold can also lead to nervousness or restlessness, especially in sensitive individuals.
• Increased Heart Rate:  Actifed-P Cold can cause an increase in heart rate (tachycardia) in some people. If you have a heart condition or high blood pressure, consult your healthcare provider before taking this medication.

Less Common Side Effects

• Allergic Reactions: Allergic reactions to Actifed-P Cold, including skin rashes, itching, swelling, or hives, are less common but possible.
• High Blood Pressure:  Actifed-P Cold can raise blood pressure in some individuals, which may be a concern for those with hypertension or cardiovascular issues.
• Headache: Although less common, some people may experience headaches as a side effect of Actifed-P Cold.
• Blurred Vision: Blurred vision is a less common side effect associated with Actifed-P Cold.
• Dizziness: Dizziness can occur in some individuals, particularly if they experience significant drowsiness.
• Difficulty Urinating:  Actifed-P Cold can lead to difficulty urinating in some individuals, especially those with prostate problems.
• Gastrointestinal Disturbances: Rarely, Actifed-P Cold can cause more severe gastrointestinal issues such as gastritis, ulcers, or bleeding.

Actifed-P Cold is one of the leading brands of (Paracetamol, Pseudoephedrine, and Triprolidine), manufactured and marketed by GlaxoSmithKline.

Presently, Actifed-P Cold is available in Tablet and Syrup Forms with the following strengths.

Actifed-P Cold Tablet:

• Paracetamol 300mg
• Pseudoephedrine 36mg
• Triprolidine 1.5mg

Actifed-P Cold Syrup:

• Paracetamol 80mg/5ml
• Pseudoephedrine 30mg/5ml
• Triprolidine 1.25mg/5ml

1. Monoamine Oxidase Inhibitors (MAOIs): Do not use Actifed-P Cold if you are taking or have taken MAOIs (a type of antidepressant) within the past 14 days. Combining Actifed-P Cold with MAOIs can lead to a potentially life-threatening condition called serotonin syndrome, which can cause symptoms like agitation, hallucinations, rapid heartbeat, and increased body temperature.
2. Other Cold or Allergy Medications: Using other cold or allergy medications that contain similar ingredients (e.g., decongestants or antihistamines) at the same time can lead to an overdose of these components. Always read labels carefully and avoid combining them unless instructed by a healthcare professional.
3. Blood Pressure Medications:  Actifed-P Cold can increase blood pressure, so using it with certain blood pressure medications, such as beta-blockers or alpha-agonists, can lead to an elevated risk of high blood pressure.
4. Anticoagulants (Blood Thinners):  Actifed-P Cold may increase the risk of bleeding when taken with anticoagulant medications like warfarin.
5. Alcohol: Excessive alcohol consumption while taking Actifed-P Cold can increase the risk of liver damage, as both Actifed-P Cold and alcohol can be taxing on the liver. It’s generally advisable to limit alcohol intake when using Actifed-P Cold.
6. Antidepressants: Some types of antidepressants, such as tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs), may interact with Actifed-P Cold, possibly leading to increased drowsiness or other side effects.
7. Urinary Retention Medications: If you are taking medications for urinary retention, Actifed-P Cold may worsen this condition. Liver Disease: Individuals with liver disease should use caution when taking Actifed-P Cold, as its components are metabolized in the liver. In cases of severe liver impairment, it’s generally best to avoid Actifed-P Cold or use it under close medical supervision.
8. Kidney Disease: If you have kidney disease, it’s important to be cautious with Actifed-P Cold, as it can have an impact on kidney function.

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