Zeespa tablet is primarily used to treat symptoms associated with irritable bowel syndrome (IBS), a gastrointestinal disorder characterized by abdominal pain, bloating, and changes in bowel habits. Following are some common and off-label uses of Zeespa Tablet:

  1. Irritable Bowel Syndrome (IBS): Zeespa is commonly used to relieve the symptoms of IBS, including abdominal pain, cramping, bloating, and irregular bowel movements.
  2. Spastic Colon: The use of Zeespa can help alleviate the symptoms of spastic colon, a condition characterized by spasms in the colon, leading to abdominal pain and changes in bowel habits.
  3. Functional Gastrointestinal Disorders: Zeespa may be used to treat other functional gastrointestinal disorders, such as functional dyspepsia and functional abdominal pain, which are associated with symptoms like pain, bloating, and discomfort.
  4. Colicky Abdominal Pain: Zeespa is sometimes used to relieve colicky abdominal pain, which can occur due to spasms in the gastrointestinal tract.
  5. Diverticular Disease: Zeespa may be used to manage symptoms associated with diverticular diseases, such as abdominal pain and bloating.

Off-label Uses of Zeespa Tablet

  1. Colicky Abdominal Pain: Zeespa has been used to alleviate colicky abdominal pain, which refers to sudden and severe pain that comes in waves and is often associated with spasms in the digestive tract.
  2. Postoperative Abdominal Pain: In some cases, Zeespa has been used to help manage postoperative abdominal pain. It may be prescribed to relax the muscles in the gastrointestinal tract and provide relief.
Zeespa Uses and Indications

What is Zeespa?

Zeespa is one of the leading brands of Mebeverine, manufactured and marketed by Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.

Zeespa Alternatives : Other Similar Brands

The following are some alternative brands of Zeespa and their manufacturers.

  • Colofac : Abbott Laboratories, Pakistan.
  • Mevever MR : Getz Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Colospas : Nabiqasim Industries (Pvt) Ltd, Pakistan.
  • Spasler-Neo : AGP (Pvt) Ltd, Pakistan.
  • Aspa : Highnoon Laboratories Ltd, Pakistan.
  • Colorest : Wilsons Pharmaceuticals, Pakistan.
  • Sameb MR : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Baver : Glitz Pharma, Pakistan.
  • Colonil : Genom Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Mibs : Shaheen Pharmaceuticals, Pakistan.

Zeespa : Available Formulations and Strengths

Presently, Zeespa is available in Tablet Form.

Zeespa Tablet : 135mg strength.

Who Should Not Use Zeespa?

Zeespa has certain contraindications, which are conditions or circumstances in which the use of Zeespa is not recommended due to potential risks or lack of effectiveness.

Hypersensitivity: Zeespa should not be used in individuals who have a known hypersensitivity or allergy to Zeespa or any of its components. If you have experienced an allergic reaction to Zeespa or similar medications in the past, it is important to avoid using it.

Severe inflammatory bowel disorders: Zeespa is not recommended for individuals with severe inflammatory bowel disorders such as ulcerative colitis or Crohn’s disease. These conditions involve inflammation of the gastrointestinal tract, and Zeespa may not be effective or may even worsen the symptoms.

Intestinal obstruction: Zeespa is contraindicated in cases of intestinal obstruction, which is a condition where the normal movement of contents through the intestines is blocked. Using Zeespa in such cases may further impede the passage of material through the intestine and potentially worsen the obstruction.

Paralytic ileus: Zeespa should not be used in individuals with paralytic ileus, a condition characterized by the paralysis or non-functioning of the intestinal muscles. The medication may further reduce intestinal motility and worsen the condition.

What is the Recommended Daily Dosage of Zeespa?

Zeespa Dose for Adults:

  • For Irritable Bowel Syndrome (IBS) and Other Functional Gastrointestinal Disorders: One Tablet of 135mg, three times a day, preferably before meals.
  • In some cases, a lower initial dosage of a half tablet of (135 mg) taken three times a day may be prescribed, which can be increased gradually if needed.

Zeespa Dose for Children:

  • Mebeverine is not typically recommended for use in children. The safety and effectiveness of mebeverine in pediatric patients have not been well established, so it’s important to consult with a pediatrician or healthcare provider for appropriate alternatives.

How Zeespa Works?

Zeespa work by blocking certain types of receptors called muscarinic receptors, which are found on the smooth muscle cells in the gastrointestinal tract. By blocking these receptors, Zeespa inhibits the action of acetylcholine, a neurotransmitter that plays a role in muscle contractions.