Valtec Tablet Uses

Valtec tablet is primarily used to treat high blood pressure (hypertension). It is also used to prevent several cardiovascular conditions such as heart attack, stroke, and heart failure. Valtec belongs to the class of drugs known as angiotensin II receptor blockers (ARBs). Following are some common and off-label uses of Valtec Tablet:

Common Uses of Valtec Tablet

1. Hypertension (High Blood Pressure): Valtec tablet is commonly used as a first-line treatment for hypertension. It helps lower blood pressure by blocking the action of angiotensin II, a hormone that constricts blood vessels. By blocking the effects of angiotensin II, Valtec helps to relax and widen the blood vessels, resulting in lowered blood pressure.
2. Heart Failure: Valtec tablet is also used for the management of heart failure. It can help improve symptoms, reduce hospitalizations, and enhance survival rates in patients with heart failure.
3. Post-Heart Attack: Valtec tablets may be used to improve outcomes and prevent further cardiac events. It helps reduce the strain on the heart and minimize the risk of future cardiovascular events.
4. Diabetic Nephropathy: Valtec tablet is beneficial in treating diabetic nephropathy, a kidney disease that occurs as a complication of diabetes. It can slow down the progression of kidney damage and reduce proteinuria (the presence of excess protein in the urine) in diabetic patients with compromised kidney function.
5. Left Ventricular Dysfunction: In patients with asymptomatic left ventricular dysfunction, Valtec tablets may be used to reduce the risk of developing symptomatic heart failure or cardiovascular events.

Off-label Uses of Valtec Tablet

1. Atrial Fibrillation: Valtec tablets may be used off-label to manage atrial fibrillation, a common heart rhythm disorder. It has been investigated for its potential to prevent the recurrence of atrial fibrillation episodes and maintain normal sinus rhythm.
2. Hypertensive Crisis: Valtec tablets may be utilized in the management of a hypertensive crisis, a severe and sudden increase in blood pressure that requires immediate intervention. It can help lower blood pressure rapidly and stabilize the patient’s condition.
3. Microalbuminuria: Valtec tablets may be used to treat microalbuminuria, a condition characterized by the presence of small amounts of albumin in the urine, which can be an early sign of kidney damage in conditions such as diabetes or hypertension.
4. Migraine Prevention: Some clinical trials suggest that Valtec tablets may be used off-label to reduce the frequency and severity of migraines. It is believed that its ability to modulate blood vessel tone and improve blood flow may contribute to its potential benefit in migraine management.

Valtec is one of the leading brands of Valsartan, manufactured and marketed by Tabros Pharma Pakistan.

Below are some available similar brands that can be used as an alternative to Valtec tablet:

• Diovan : Novartis Pharma (Pakistan) Ltd.
• Valstar : (CCL) Consolidated Chemical Laboratories (Pvt) Ltd, Pakistan.
• Nuval : Pharmevo Pakistan (Pvt) Ltd.
• Alevia : Atco Laboratories Ltd, Pakistan.
• Angiotan : Efroz Chemical Industries (Pvt) Ltd, Pakistan.
• Valid : Scilife Pharmaceuticals (Pvt) Ltd, Pakistan.
• Diaval : Ethical Laboratories (Pvt) Ltd, Pakistan.
• Listan : Lexicon Pharmaceuticals (Pvt) Ltd, Pakistan.
• Tulurik : Medisure Laboratories Pakistan (Pvt) Ltd.
• Valkin : Kanel Pharmaceuticals, Pakistan.

Presently, Valtec is available in Tablet Form with the following strengths.

Valtec Tablets : 40mg, 80mg, and 160mg strengths.

Valtec has specific contraindications, which are situations or conditions in which the use of Valtec is not recommended due to the potential risks involved.

• Hypersensitivity or Allergy: Individuals who have a known hypersensitivity or allergic reaction to Valtec or any other component of the medication should avoid its use.
• Pregnancy: Valtec is contraindicated during pregnancy, especially during the second and third trimesters. It may cause harm to the developing fetus, including severe fetal abnormalities or even death. Alternative medications should be considered for pregnant women with hypertension.
• Breastfeeding: Valtec is not recommended during breastfeeding. The drug can pass into breast milk and potentially harm the nursing infant. Safer alternatives should be considered, and if Valtec is deemed necessary, breastfeeding should be discontinued.
• Severe Hepatic Impairment: Valtec is contraindicated in patients with severe liver impairment or liver disease. The medication is metabolized in the liver, and severe hepatic impairment can affect the metabolism and clearance of the drug.
• Dual Blockade of the Renin-Angiotensin System: Concurrent use of Valtec with another medication that affects the renin-angiotensin system, such as an angiotensin-converting enzyme (ACE) inhibitor or aliskiren, is generally not recommended due to an increased risk of hypotension, hyperkalemia, and renal dysfunction.
• Angioedema: Valtec should be avoided in individuals who have a history of angioedema (swelling of the face, lips, tongue, or throat) associated with previous use of an ACE inhibitor or angiotensin receptor blocker (ARB), as it may increase the risk of angioedema recurrence.

Valtec Dose for Hypertension (High Blood Pressure):

• One tablet of 80mg once daily.
• The dosage may be increased to Two Tablets of 160mg per day, depending on the individual’s blood pressure response.

Valtec Dose for Heart Failure:

• One Tablet of 40mg twice daily.
• The dosage may be increased to One Tablet of 160mg twice daily, based on the patient’s response and tolerability.

Valtec Dose for Post-Heart Attack:

• One Tablet of 40mg once daily.
• The dosage may be increased to One tablet of 160mg twice daily, depending on the individual’s response and tolerability.

Valtec Dose for Diabetic Nephropathy:

• One Tablet of 80mg once daily.
• The dosage may be increased to Two Tablets of 160mg per day, depending on the patient’s response and tolerability.

Valtec is an angiotensin II receptor blocker (ARB) that exerts its therapeutic effects through its mode of action. Angiotensin II is a hormone that plays a key role in regulating blood pressure and cardiovascular function. Valtec selectively blocks the angiotensin II type 1 (AT1) receptors, preventing the binding of angiotensin II to these receptors. This action leads to a reduction in peripheral vascular resistance, making it easier for blood to flow through the vessels. Ultimately Valtec provides a blood pressure-lowering effect.

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