Unix tablet is primarily used for its analgesic (pain-relieving) and anti-inflammatory properties. It belongs to the non-steroidal anti-inflammatory drug (NSAID). Following are some common uses of Unix Tablets:
- Pain Relief: Unix tablet is used for relieving mild to moderate pain, such as headache, dental pain, menstrual pain, post-operative pain, and musculoskeletal pain.
- Inflammatory Conditions: Unix tablet is commonly used to reduce inflammation in conditions like arthritis (including osteoarthritis and rheumatoid arthritis), gout, ankylosing spondylitis, and other musculoskeletal disorders.
- Fever reduction: Unix tablets can help reduce fever associated with various infections and inflammatory conditions.
- Dysmenorrhea: Unix tablets can be used to alleviate pain and cramping associated with menstrual periods.
Off-label Uses of Unix Tablet
- Acute Respiratory Tract Infections: Unix tablet can used in respiratory tract infections, including acute bronchitis and upper respiratory tract infections. However, it is used off-label in these conditions.
- Acute Otitis Media: Unix tablet has been also used as a potential treatment for acute otitis media (middle ear infection) in children. However, it is used off-label in this condition and is not generally accepted due to concerns about potential adverse effects.
- Chronic Inflammatory Conditions: Unix tablets may have a role in the treatment of chronic inflammatory conditions such as chronic obstructive pulmonary disease (COPD), inflammatory bowel disease (IBD), and psoriasis. However, further research is needed to establish its efficacy and safety in these conditions.
What is Unix?
Unix is one of the leading brands of Nimesulide, manufactured and marketed by Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
Unix Alternatives : Other Similar Brands
Following are some alternative brands of Unix and their manufacturers.
- Nims : Sami Pharmaceuticals, Pakistan.
- Nise : Pahrmevo (Pvt) Ltd, Pakistan.
- Modact IR : Platinum Pharmaceuticals, Pakistan.
- Mexidon : Searl Pakistan (Pvt) Ltd.
- Amsolide : Amson Vaccines & Pharma (Pvt) Ltd.
- Artilide : Global Pharmaceuticals.
- Geoslide : Geofman Pharmaceuticals.
- Nugesic : Helix Pharma (Pvt) Ltd.
- Orina : Shrooq Pharmaceuticals.
- Pensulide : Don Valley Pharmaceuticals (Pvt) Ltd.
Unix : Available Formulations and Strengths
Presently Unix is available in Tablet Form with the following strength.
Unix Tablet : 100mg strength.
Who Should Not Use Unix?
Unix has certain contraindications, which are specific circumstances or conditions in which the use of Unix is not recommended due to the potential risks involved.
Hypersensitivity or allergic reactions: Individuals who have a known hypersensitivity or allergy to Unix or any other NSAIDs should not use this medication.
History of allergic reactions or asthma: Unix can potentially trigger allergic reactions, including severe skin reactions or exacerbation of asthma symptoms, in individuals with a history of such conditions.
Active or history of peptic ulcer disease: Unix can increase the risk of gastrointestinal bleeding, ulcers, and perforation. Therefore, it is contraindicated in individuals with an active peptic ulcer or a history of gastrointestinal bleeding or perforation.
Severe liver or kidney impairment: Unix is metabolized primarily in the liver, and it may cause liver toxicity in some cases. Therefore, it is contraindicated in individuals with severe liver impairment or active liver disease. Additionally, caution should be exercised in individuals with severe kidney impairment.
Bleeding disorders: Unix can affect platelet function and prolong bleeding time. It should be avoided in individuals with known bleeding disorders or those who are at risk of excessive bleeding.
Pregnancy and lactation: Unix is generally contraindicated during pregnancy, especially in the third trimester, as it may have adverse effects on the fetus. It is also not recommended during breastfeeding.
Children: Unix is contraindicated in infants under the age of 12 months due to an increased risk of liver toxicity. Its use in children and adolescents should be carefully considered, and the potential risks and benefits should be evaluated by a healthcare professional.
What is the Recommended Daily Dosage of Unix?
Unix Dose for Adults:
- The usual recommended oral dose of Unix for adults is 1 to 2 tablets taken once daily, typically with food.
- However, the exact dose and frequency may vary based on the specific indication and severity of symptoms.
- It’s important to note that the total daily dose should not exceed two tablets of Unix.
How Unix Works?
Unix tablet works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-2, which are involved in the production of prostaglandins, mediators of pain, inflammation, and fever.
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