Modact IR tablet is an analgesic medication that is primarily used to treat pain and inflammation. It belongs to a class of drugs known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).

The following are common uses and indications of Modact IR Tablet:

  1. Pain Management: Modact IR tablet is used to relieve mild to moderate pain. This may include conditions like headache, toothache, menstrual cramps, musculoskeletal pain, and other types of acute or chronic pain.
  2. Inflammatory Conditions: Modact IR tablet is also used to reduce inflammation in conditions like osteoarthritis and rheumatoid arthritis. It helps to alleviate pain, swelling, and stiffness associated with these conditions.
  3. Fever: Modact IR tablet is sometimes used to lower fever in individuals with infections or other fever-inducing conditions.
  4. Dysmenorrhea: Modact IR tablet can be used to relieve the pain and discomfort associated with menstrual cramps.
  5. Other Painful Conditions: In some cases, healthcare providers may prescribe Modact IR tablets for pain associated with minor injuries or post-operative discomfort.

Off-label Uses of Modact IR Tablet

  1. Dental Pain: Modact IR tablets may be used off-label for managing dental pain and discomfort, especially in cases where there is inflammation associated with dental procedures or conditions.
  2. Migraine: In some cases, Modact IR tablet may be considered a treatment option for acute migraine attacks, particularly when other analgesics have not provided adequate relief.
  3. Postoperative Pain: It has been considered for use in managing postoperative pain after certain surgical procedures, particularly when there is associated inflammation.
  4. Acute Gouty Arthritis: Some healthcare providers may consider Modact IR tablet as an alternative treatment for acute gout attacks in certain cases.
  5. Osteoarthritis of the Hip or Knee: While Modact IR tablet is commonly used for osteoarthritis, its use for specific joints (e.g., hip or knee) may be considered off-label.
Modact IR Tablet Uses and Indications

What is Modact IR?

Modact IR is one of the leading brands of Nimesulide with Immediate Release formulation, manufactured and marketed by Platinum Pharmaceuticals (Pvt) Ltd, Pakistan.

Modact IR Tablet’s Alternatives : Other Similar Brands

Following are some alternative brands of Modact IR and their manufacturers.

  • Nims : Sami Pharmaceuticals, Pakistan.
  • Nise : Pahrmevo (Pvt) Ltd, Pakistan.
  • Unix : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Mexidon : Searl Pakistan (Pvt) Ltd.
  • Amsolide : Amson Vaccines & Pharma (Pvt) Ltd.
  • Artilide : Global Pharmaceuticals.
  • Geoslide : Geofman Pharmaceuticals.
  • Nugesic : Helix Pharma (Pvt) Ltd.
  • Orina : Shrooq Pharmaceuticals.
  • Pensulide : Don Valley Pharmaceuticals (Pvt) Ltd.

Modact IR : Available Formulations and Strengths

Presently, Modact IR is available in Tablet form.

  • Modact IR Tablet : 100mg strength.

Who Should Not Use Modact IR Tablet? – Contraindications

Modact IR has several contraindications, which are situations or conditions where the use of this medication is not recommended due to the potential for harm.

  1. Hypersensitivity or Allergy: Individuals with known hypersensitivity or allergy to Nimesulide or any other NSAID (nonsteroidal anti-inflammatory drug) should not take Modact ID tablets.
  2. History of Asthma, Urticaria, or Other Allergic Reactions to NSAIDs: Modact IR tablets should be avoided in individuals with a history of severe allergic reactions, including asthma, urticaria (hives), or other allergic symptoms after taking NSAIDs.
  3. Active Peptic Ulcer Disease or Gastrointestinal Bleeding: Modact IR tablet can increase the risk of gastrointestinal bleeding, so it is contraindicated in individuals with active peptic ulcers or a history of gastrointestinal bleeding.
  4. Severe Heart Failure: Modact IR tablet may exacerbate heart failure, so it is contraindicated in individuals with severe congestive heart failure.
  5. Severe Renal Impairment or End-Stage Renal Disease: Modact IR tablet is contraindicated in individuals with severe renal impairment or end-stage renal disease, as it can further impair kidney function.
  6. Severe Hepatic Impairment: Modact IR tablet is contraindicated in individuals with severe liver impairment or active liver disease.
  7. Third Trimester of Pregnancy: Modact IR tablet is contraindicated in the third trimester of pregnancy due to potential risks to the fetus and complications during delivery.
  8. Breastfeeding: Modact IR tablet is not recommended for use during breastfeeding, as it may pass into breast milk and could potentially harm the nursing infant.
  9. Children under 12 Years: In some countries, Modact IR tablet is contraindicated in children under 12 years of age due to concerns about its safety profile.
  10. Coagulation Disorders or Anticoagulant Therapy: Modact IR tablets may increase the risk of bleeding, so it is contraindicated in individuals with coagulation disorders or those taking anticoagulant medications.

What is the Recommended Daily Dosage of Modact IR Tablet?

Modact IR Tablet for Pain and Inflammation:

  • Adults: One tablet of 100mg, twice a day. In some cases, an initial dose of 200 mg may be taken on the first day, followed by 100 mg twice a day.
  • Elderly: Lower doses may be recommended for elderly patients, as they may be more susceptible to certain side effects.
  • Children (12 to 18 years): The recommended dose for children is typically based on their weight and is usually in the range of 50 mg to 100 mg twice a day.

Modact IR Tablet for Fever:

  • Adults: Once tablet of 100mg, twice a day.
  • Children (12 to 18 years): The recommended dose for fever is typically based on their weight and is usually in the range of 50 mg to 100 mg twice a day.

How Modact IR Works?

Modact IR tablet is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of prostaglandins. Prostaglandins are chemicals that cause pain and inflammation. By blocking the production of prostaglandins, Modact IR tablet can help to reduce pain and inflammation.

Modact IR tablets also work by inhibiting the enzyme cyclooxygenase-2 (COX-2). COX-2 is an enzyme that is involved in the production of prostaglandins. By inhibiting COX-2, Modact IR tablet can help to reduce pain and inflammation.