Spiano tablet is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation in various conditions.

The following are some common uses and indications of Spiano Tablet:

  1. Pain Relief: Spaino tablet is used to alleviate mild to moderate pain. This can include pain due to conditions like osteoarthritis, rheumatoid arthritis, dental pain, musculoskeletal disorders, and postoperative pain.
  2. Inflammatory Conditions: The use of Spiano tablet is effective in reducing inflammation associated with conditions like arthritis, including both osteoarthritis and rheumatoid arthritis.
  3. Musculoskeletal Disorders: Spiano tablet can be used in conditions like ankylosing spondylitis, where there is inflammation of the joints between the vertebrae of the spine and in the joints between the spine and the pelvis.
  4. Dental Pain: Spiano tablets may be prescribed for dental pain, especially in situations where there’s inflammation of the gums or surrounding tissues.
  5. Painful Menstruation (Dysmenorrhea): Spaino tablet may be used to relieve pain associated with menstrual cramps.
  6. Postoperative Pain: Spiano tablets can be prescribed after surgical procedures to manage pain and inflammation.
  7. Soft Tissue Injuries: Spaino tablet may be used in cases of sprains, strains, or other soft tissue injuries where there is pain and inflammation.

Off-label Uses of Spiano Tablet

  1. Migraine Headaches: Some healthcare providers may prescribe Spaino tablets for the treatment of migraine headaches, particularly in cases where other treatments have been ineffective.
  2. Fever: While not a primary use, the Spaino tablet may be used to reduce fever in some situations.
  3. Dysmenorrhea with Heavy Bleeding: Spaino tablet may be used to manage dysmenorrhea (painful menstruation) associated with heavy bleeding.
  4. Pain due to Gout: Spiano tablets may be used to manage pain and inflammation associated with gout, a type of arthritis caused by the buildup of uric acid crystals in the joints.
  5. Back Pain: Spaino tablet may be prescribed for chronic back pain, particularly if it is related to inflammatory conditions.
  6. Pain from Inflammatory Bowel Disease (IBD): Spaino tablet may be used off-label to manage pain in individuals with inflammatory bowel diseases like Crohn’s disease or ulcerative colitis.
  7. Painful Conditions of the Ear, Nose, and Throat (ENT): Spaino tablet may be used to alleviate pain and inflammation in conditions affecting the ear, nose, and throat, such as tonsillitis or otitis media.
  8. Pain in Cancer Patients: Spaino tablet may be considered for pain relief in cancer patients, especially in cases where inflammation is a contributing factor.
Spiano Tablet Uses and Indications

What is Spiano?

Spiano is one of the leading brands of Aceclofenac, manufactured and marketed by Continental Pharmaceuticals (Pvt) Ltd, Pakistan.

Spiano Tablet’s Alternatives : Other Similar Brands

The following are some alternative brands of Spiano and their manufacturers.

  • Acemed : Novartis, Pakistan
  • Airtal : Highnoon Laboratories (Pvt) Ltd, Pakistan.
  • Dyclo-Ace : Indus Pharma (Pvt) Ltd.
  • Acelish : Platinum Pharmaceuticals (Pvt.) Ltd.
  • Alkeris : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Acecol : Maple Pharmaceuticals (Pvt) Ltd.
  • Actavis : Genix Pharma (Pvt) Ltd.
  • Acenac : S.J. & G. Fazul Ellahie (Pvt) Ltd.
  • Pefree : Efroze Chemical Industries (Pvt) Ltd.
  • Ophen : Standpharm Pakistan (Pvt) Ltd.

Spiano : Available Formulations and Strengths

Presently, Spiano is available in tablet form.

Spiano Tablet : 100mg strength.

Who Should Not Use Spiano? – Contraindications

Spaino tablets should not be used in certain situations due to potential risks or interactions with other conditions or medications.

  1. Hypersensitivity or Allergy: Individuals who have a known hypersensitivity or allergy to Aceclofenac or any of its components should not use Spiano tablet.
  2. Active Peptic Ulcer Disease: Spaino tablet can exacerbate peptic ulcers or gastric bleeding. It is contraindicated in individuals with active peptic ulcer disease.
  3. History of Gastrointestinal Bleeding or Perforation: If a person has a history of gastrointestinal bleeding or perforation, Spaino tablet should be avoided.
  4. Severe Heart Failure: It is contraindicated in cases of severe congestive heart failure due to the potential for sodium and water retention associated with NSAIDs.
  5. Severe Renal Impairment: Spaino tablet can lead to renal impairment. It is contraindicated in individuals with severe kidney dysfunction.
  6. Severe Hepatic Impairment: Individuals with severe liver disease should avoid using Spaino tablet due to the potential for further liver damage.
  7. Pregnancy and Breastfeeding: Spaino tablet is generally contraindicated during pregnancy, especially in the third trimester, as it may harm the fetus. It is also contraindicated during breastfeeding as it may pass into breast milk.
  8. Children and Adolescents: Spaino tablet is typically not recommended for use in children and adolescents under 18 years of age, unless specifically prescribed by a healthcare provider.
  9. Use with Specific Medications: Spaino tablet may interact with certain medications, such as anticoagulants (blood thinners), other NSAIDs, corticosteroids, and some medications used for high blood pressure. It’s important to inform your healthcare provider of all medications you are taking.
  10. History of Asthma, Rhinitis, or Urticaria Induced by NSAIDs: Individuals who have a history of asthma, rhinitis, or urticaria induced by NSAIDs should avoid Spaino tablets.
  11. Inflammatory Bowel Disease (IBD): Spaino tablet should be used with caution in individuals with a history of inflammatory bowel disease, as it can exacerbate the condition.

What is the Recommended Daily Dosage of Spiano Tablet?

Spiano Tablet Dose for Pain and Inflammation in Adults:

  • One tablet of 100mg, once or twice a day, taken with food or milk.
  • The total daily dose should not exceed 200 mg.

Spiano Tablet Dose for Osteoarthritis and Rheumatoid Arthritis in Adults:

  • One tablet of 100mg, once or twice a day, taken with food or milk.
  • The total daily dose should not exceed 200 mg.

Spiano Tablet Dose for Dysmenorrhea (Menstrual Pain) in Adults:

  • One tablet of 100mg, once or twice a day, taken with food or milk.
  • The total daily dose should not exceed 200 mg.

Spiano Tablet Dose for Geriatric Patients:

  • Lower doses may be recommended for elderly individuals to reduce the risk of side effects.

Spiano Tablet Dose for Pediatric Patients:

  • The use of Spiano in children and adolescents under 18 years of age may require specific considerations and should be determined by a healthcare provider.

How Spiano Works?

Spaino is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties. It works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are inflammatory mediators that play a role in pain, swelling, and inflammation. Spaino is a more selective inhibitor of COX-2 than COX-1, which may give it a better safety profile than other NSAIDs.

In addition to inhibiting COX, Spaino also has other anti-inflammatory effects, such as inhibiting the production of cytokines and other inflammatory mediators. It also has chondroprotective effects, meaning that it can help to protect cartilage from damage.