Praz is a medication that belongs to a class of drugs called benzodiazepines. It is used for several medical conditions, primarily related to the management of anxiety and panic disorders.

The following are some common uses and indications of Praz Tablet

  1. Anxiety Disorders: Praz tablet is used to treat various forms of anxiety disorders, including generalized anxiety disorder (GAD). It helps alleviate symptoms like excessive worry, restlessness, and tension.
  2. Panic Disorder: Praz tablet is often used for the treatment of panic disorder, which involves sudden and recurrent episodes of intense fear or discomfort (panic attacks). Praz tablet can help reduce the frequency and severity of these episodes.
  3. Social Anxiety Disorder: In some cases, Praz tablet may be used to alleviate symptoms of social anxiety disorder, particularly when other treatments have not been effective.
  4. Anxiety Associated with Depression: Praz tablet may be prescribed when anxiety is a significant component of a person’s depression.
  5. Panic Attacks in Post-Traumatic Stress Disorder (PTSD): Praz tablet may be used to manage acute symptoms of panic attacks in individuals with PTSD.

Off-label Uses of Praz Tablet

  1. Insomnia: While Praz tablet is not a first-line treatment for insomnia, it may be used off-label in some situations when other sleep medications have been ineffective. However, its use for insomnia is generally limited due to the risk of dependence and withdrawal.
  2. Alcohol Withdrawal: Praz tablet may be used in the management of alcohol withdrawal symptoms, particularly in the short-term treatment of alcohol withdrawal syndrome. It can help reduce anxiety and prevent seizures associated with alcohol withdrawal.
  3. Premenstrual Syndrome (PMS): Some healthcare providers may prescribe Praz tablet to manage severe PMS symptoms, including anxiety and irritability. However, this is not a common or recommended treatment for PMS.
  4. Tinnitus: Tinnitus is the perception of ringing or other noises in the ears. Praz tablet may be prescribed in some cases to help manage the anxiety and stress associated with severe tinnitus symptoms.
  5. Essential Tremor: Praz tablet may be used off-label to help alleviate the symptoms of essential tremor, a neurological disorder characterized by involuntary shaking of certain body parts. It may help reduce anxiety related to the tremors.
  6. Post-Traumatic Stress Disorder (PTSD): In some cases, Praz tablet may be prescribed as an adjunctive treatment for individuals with PTSD who have not responded to other medications. However, other medications like selective serotonin reuptake inhibitors (SSRIs) and psychotherapy are typically preferred for PTSD.
  7. Muscle Spasms: Praz tablet may be used off-label to help relieve muscle spasms or tension, although it is not a first-line treatment for these conditions.
Paraz Tablet Uses and Indications

What is Praz?

Praz is one of the leading brands of Alprazolam, manufactured and marketed by Getz Pharmaceuticals (Pvt) Ltd, Pakistan.

Praz Tablet’s Alternatives : Other Similar Brands

The following are Some Alternative Brands of Praz and Their Manufacturers.

  • Xanax : Pfizer Laboratories Inc.
  • Alp : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Azolam : Martin Dow Pharma, Pakistan.
  • Hilaxin : Himont Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Neuxam : Standpham Pakistan (Pvt) Ltd.
  • Pralzo : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Neram : Genuix Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Xylepam : Brookes Pharmaceutical Laboratories (Pvt) Ltd, Pakistan.
  • Pinix : Adamjee Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Zenith : Ferozsons Laboratories Ltd, Pakistan.

Praz Tablet’s : Available Formulations and Strengths

Presently, Praz is available in Tablet form.

Praz Tablet : 0.25mg, 0.5mg, and 1mg strengths.

Who Should Not Use Praz Tablet? – Contraindications

Praz tablet is a medication that should not be used in certain situations due to potential risks and interactions with other medications or medical conditions.

  1. Hypersensitivity or Allergy: Individuals who have had an allergic reaction to Alprazolam or any of its components should not use Praz tablets.
  2. Narrow-Angle Glaucoma: Praz tablet can increase the pressure within the eye, which can be dangerous for individuals with narrow-angle glaucoma.
  3. Severe Respiratory Insufficiency: Praz tablet can suppress respiration, especially in high doses or when combined with other substances that depress the central nervous system. Therefore, it should be avoided in individuals with severe respiratory insufficiency.
  4. Myasthenia Gravis: Praz tablet can worsen muscle weakness in individuals with myasthenia gravis, a neuromuscular disorder.
  5. Severe Liver Disease: Individuals with severe liver disease may not be able to metabolize Praz tablet properly, which can lead to an accumulation of the drug in the body. This can increase the risk of side effects and toxicity.
  6. Acute Angle-Closure Glaucoma: Praz tablet can precipitate an acute attack of angle-closure glaucoma in individuals with this condition.
  7. Pregnancy and Breastfeeding: Praz tablet can cross the placenta and may be excreted in breast milk. It should be used with caution in pregnant and breastfeeding individuals, and the potential benefits should be weighed against the potential risks.
  8. Alcohol and Substance Abuse: Individuals with a history of alcohol or substance abuse may be at a higher risk of developing dependence on Praz tablet.
  9. Severe Depression or Suicidal Tendencies: Praz tablet can potentially worsen depressive symptoms, especially in individuals with severe depression or suicidal tendencies.
  10. Elderly Patients: Older adults may be more sensitive to the sedative effects of Praz tablet. Caution and lower doses are often advised.
  11. Porphyria: Praz tablet may worsen porphyria, a group of rare genetic disorders affecting enzymes in the heme biosynthesis pathway.

What is the Recommended Daily Dosage of Praz Tablet?

Praz Tablet Dose for Anxiety Disorders:

  • For Adults: One tablet of 0.25 to 0.5 mg, taken orally three times per day.
  • The dosage can be adjusted as needed, but it is generally recommended to start with the lowest effective dose.
  • For Elderly Patients or Those with Liver Disease: Lower initial doses are often recommended due to the potential for increased sensitivity to the drug.

Praz Tablet Dose for Panic Disorder:

  • One tablet of 0.5 mg to 1 mg taken orally in divided doses.
  • Again, the dosage may be adjusted based on individual response.

Praz Tablet Dose for Insomnia:

  • Adults: One tablet of 0.25 to 0.5 mg at bedtime.
  • The dose may be increased as needed but should not exceed 4 mg per day.

Praz Tablet Dose for PMS:

  • Adults: One tablet of 0.25 to 0.5 mg 3 times a day during the premenstrual and menstrual phases of the cycle.
  • The dose may be increased as needed but should not exceed 4 mg per day.

How Praz Works?

Praz tablet is a benzodiazepine medication that works by binding to GABA receptors in the brain. GABA is a neurotransmitter that inhibits the activity of other neurons. When Praz tablet binds to GABA receptors, it enhances the effect of GABA, which leads to a calming effect.