Phlogin Capsule Uses

Phlogin capsule is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for mild-to-moderate painful and inflammatory conditions, including:

1. Pain Relief: Phlogin is commonly used to relieve mild to moderate pain, such as headaches, dental pain, musculoskeletal pain (e.g., back pain, joint pain), menstrual cramps, and postoperative pain.
2. Inflammatory Conditions: Phlogin is also used to reduce inflammation and swelling associated with conditions like rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, and other musculoskeletal disorders.
3. Postoperative Pain and Inflammation: Phlogin may be used after surgical procedures to manage pain and reduce swelling and inflammation at the surgical site.
4. Migraine: Phlogin can be used for the treatment of acute migraine attacks, although specific migraine-specific medications are often preferred.
5. Dysmenorrhea: Phlogin is sometimes used to relieve the pain and discomfort associated with menstrual cramps.

Off-label Uses of Phlogin Capsule

1. Tendonitis and Bursitis: Phlogin may be used off-label to manage pain and inflammation associated with tendonitis (inflammation of tendons) and bursitis (inflammation of bursae, fluid-filled sacs that cushion joints).
2. Postoperative Inflammation: Phlogin is commonly used to manage postoperative pain, but it may also be used off-label to reduce inflammation after surgical procedures.
3. Actinic Keratosis: Phlogin Gel is used for the treatment of actinic keratosis, a skin condition caused by sun damage, which can lead to the development of skin cancer.

Phlogin is one of the leading brands of Diclofenac Sodium, manufactured and marketed by Brookes Pharmaceutical Laboratories (Pakistan) Ltd.

Following are some alternative brands of Phlogin and their manufacturers.

• Dicloran : Sami Pharmaceuticals, Pakistan.
• Voltral : Novartis Pharma Pakistan.
• Artifen : Abbott Laboratories (Pakistan) Ltd.
• Voren : Asian Continental (Pvt) Ltd, Pakistan.
• Dyclo : Indus Pharmaceuticals, Pakistan.
• Fastaid : Platinum Pharmaceuticals, Pakistan.
• Mobikare : Barrett Hodgson (Pvt) Ltd, Pakistan.
• Panslay : Getz Pharmaceuticals, Pakistan.
• Arnil : Brookes Pharmaceutical Laboratories (Pakistan) Ltd.
• Motaar : Standpharm Pakistan (Pvt) Ltd.
• Orthofenac : Bosch Pharmaceuticals, Pakistan.
• Magnofenac : AGP (Pvt) Ltd, Pakistan.
• Remethan : High-Q Pharmaceuticals, Pakistan.

Presently, Phlogin is available in Capsules, Get, and Injection forms with the following strengths.

Phlogin Capsule : 50mg strength

Phlogin SR Capsule : 100mg strength.

Phlogin Gel : 1.16%w/w strength.

Phlogin Injection : 25mg/ml strength.

Phlogin has several contraindications, and it is important to be aware of these before using Phlogin.

Allergy or Hypersensitivity: Individuals who have a known allergy or hypersensitivity to Phlogin or other nonsteroidal anti-inflammatory drugs (NSAIDs) should not use Phlogin, as it may lead to severe allergic reactions.

Asthma, Rhinitis, or Urticaria: Phlogin can potentially trigger or worsen asthma, allergic rhinitis (hay fever), or urticaria (hives) in some individuals who are susceptible to these conditions. It is contraindicated in people with a history of these conditions associated with NSAID use.

Active Peptic Ulcer Disease: Phlogin is known to increase the risk of gastrointestinal ulcers and bleeding. Therefore, it is contraindicated in individuals with an active peptic ulcer or a history of gastrointestinal bleeding.

Severe Heart Failure: Phlogin is contraindicated in individuals with severe heart failure, as it can worsen fluid retention and strain on the heart.

Severe Liver or Kidney Dysfunction: Individuals with severe liver or kidney impairment may not be able to adequately metabolize or excrete Phlogin, leading to an increased risk of side effects. Therefore, it is contraindicated in these patients.

Third Trimester of Pregnancy: Phlogin is contraindicated during the third trimester of pregnancy, as it may pose risks to the fetus, including delayed labor, premature closure of the ductus arteriosus, and potential harm to the cardiovascular system.

Phlogin Dose for Pain Relief:

• For mild to moderate pain: One Capsule of 50mg, two to three times a day.
• The maximum daily dose is often 150 mg.

Phlogin Dose for Osteoarthritis and Rheumatoid Arthritis:

• One Capsule of 50mg, two to three times a day. Depending on the individual’s response.
• The dose may be adjusted up to a maximum of 150 mg per day.

Phlogin Dose for Ankylosing Spondylitis:

• 1 to 2 Capsules of 100mg, two times a day, with a maximum daily dose of 200 mg.

Phlogin works by inhibiting the enzyme cyclooxygenase (COX), specifically COX-1 and COX-2. This inhibition leads to a decrease in the production of certain prostaglandins, which are chemical messengers involved in inflammation, pain, and fever.