Gixer syrup is an antihistamine medication that is primarily used to relieve allergy symptoms. It is mostly recommended for children and adults where a low dose of medicine is needed. The following are some common uses and indications of Gixer Syrup:

  1. Allergic Rhinitis: Gixer syrup is commonly used to manage allergic rhinitis, also known as hay fever. It helps alleviate symptoms caused by allergens such as pollen, dust mites, pet dander, or mold spores. This includes sneezing, nasal congestion, itching, and a runny or stuffy nose.
  2. Seasonal Allergies: Seasonal allergies, which occur during specific times of the year, can significantly impact a person’s quality of life. Gixer syrup is often used to provide relief from symptoms related to seasonal allergic reactions triggered by pollen, grass, or certain plants.
  3. Perennial Allergies: Perennial allergies are ongoing allergies that persist year-round due to triggers like dust mites, pet dander, or mold. The use of Gixer syrup can help manage the symptoms associated with perennial allergic rhinitis, providing relief from chronic sneezing, nasal congestion, and itching.
  4. Urticaria (Hives): Gixer syrup is effective in relieving symptoms of acute and chronic urticaria in both adults and children. Urticaria, commonly known as hives, manifests as itchy, raised, red, or white bumps on the skin. Using Gixer helps reduce itching and the appearance of hives, providing relief for the individual.
  5. Allergic Conjunctivitis: Gixer syrup can also help alleviate symptoms of allergic conjunctivitis, which is inflammation of the eyes due to an allergic reaction. Itchy, watery, and red eyes are common symptoms of this condition, and Gixer can provide relief from these symptoms.
  6. Eczema and Allergic Skin Conditions: Gixer syrup can be used to help alleviate itching and reduce skin inflammation associated with eczema and other allergic skin conditions.

Off-label Uses of Gixer Syrup

  1. Pruritus (Itching): Gixer syrup may be used off-label to help alleviate itching associated with various conditions such as pruritus associated with liver disease, kidney disease, or certain dermatological conditions like atopic dermatitis or contact dermatitis.
  2. Allergic Reactions to Medications: Gixer syrup may be used off-label to manage allergic reactions or hypersensitivity reactions to certain medications. It can help reduce symptoms such as itching, hives, or rash.
  3. Allergic Reactions to Vaccinations: Gixer syrup may be used off-label to manage mild allergic reactions or itching that can occur after receiving certain vaccines. It may help relieve symptoms and provide comfort.
  4. Mast Cell Activation Syndrome (MCAS): Mast cell activation syndrome is a condition characterized by an abnormal response of mast cells, resulting in various symptoms including flushing, itching, and hives. Gixer syrup may be used off-label to help manage these symptoms.
Gixer Syrup Uses and Indications

What is Gixer?

Gixer Syrup is one of the leading brands of Cetirizine HCI in oral liquid form, manufactured and marketed by Barrett Hodgson Pakistan (Pvt) Ltd.

Gixer Alternatives : Other Cetirizine Brands

The following are some alternative brands of Gixer Syrup and their manufacturers.

Rigix : AGP Pharma, Pakistan.

Zyrtec : GlaxoSmithKline Pharmaceuticals Ltd (GSK).

Sedil : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

Baydal : Bayer Schering Pharmaceuticals.

Incidal-Neo : Bayer Schering Pharmaceuticals.

Gixer : Barrett Hodgson Pakistan (Pvt) Ltd.

Cetrix : Saffron Pharmaceuticals, Pakistan.

Cerzine : Pharmevo (Pvt) Ltd, Pakistan.

Dicet : Sharooq Pharmaceuticals, Pakistan.

Tarcit : Searl Pakistan (Pvt) Ltd.

Arix : Tabros Pharma, Pakistan.

Zanlan : Novartis, Pakistan.

Arozine : Global Pharmaceuticals, Pakistan.

Rex : Albro Pharma (Pakistan).

Gixer : Available Formulations and Strengths

Presently, Gixer is available in Syrup and Tablet forms.

Gixer Syrup : 5mg/5ml strength.

Gixer Tablet : 10mg strength.

Who Should Not Use Gixer?

Gixer syrup is generally considered safe and well-tolerated when used as directed. However, there are some contraindications and precautions to consider.

  • Hypersensitivity: Individuals who have a known hypersensitivity or allergy to Gixer or any of the ingredients in the syrup should not use the medication. Allergic reactions can range from mild skin rashes to more severe symptoms like difficulty breathing and anaphylaxis.
  • Severe Renal Impairment: Gixer is primarily eliminated from the body through the kidneys. In cases of severe renal impairment, the clearance of Gixer may be reduced. Therefore, Gixer syrup should be used with caution or avoided in individuals with severe renal impairment.

It is important to note that while Gixer is generally considered safe for most individuals, caution should be exercised in certain populations, including:

  • Pregnant and Nursing Women: Gixer syrup should be used with caution during pregnancy and breastfeeding. It is important to consult with a healthcare professional to weigh the potential benefits against potential risks to the fetus or nursing baby.
  • Children: Gixer syrup is commonly used in children, but dosage adjustments may be required based on age and weight. It is important to follow the recommended pediatric dosage guidelines and consult with a healthcare professional for personalized advice.
  • Elderly Individuals: Elderly individuals may be more susceptible to certain side effects of Gixer, such as drowsiness. Dosing adjustments may be necessary based on individual response and renal function.

Recommended Daily Dosage of Gixer Syrup

Gixer Syrup for Allergic Rhinitis:

  • Adults and Children (12 years and older): 10 mg (10 ml of syrup) once daily.

Gixer Syrup for Chronic Urticaria:

  • Adults and Children (12 years and older): 10 mg (10 ml of syrup) once daily.

Gixer Syrup for children younger than 12 years old, the dose will depend on their age and weight, and it should be determined by a healthcare professional. The pediatric dosing for cetirizine syrup is typically as follows:

  • Children 6 to 11 years old: 5 mg (5 ml of syrup) once daily.
  • Children 2 to 5 years old: 2.5 mg (2.5 ml of syrup) once daily.

How Gixer Works?

Gixer acts as a selective antagonist, primarily targeting histamine H1 receptors. These receptors are found in various cells throughout the body, including those in the respiratory system, blood vessels, and skin. By binding to these receptors, Gixer prevents the interaction of histamine with the receptors and blocks the histamine-mediated signaling pathways.