Femme is a medication that belongs to a class of drugs known as H2 receptor antagonists. It is primarily used to treat conditions related to excess stomach acid production. The following are some common uses and indications of Femme Tablets:

  1. Gastric and Duodenal Ulcers: Femme Tablet is used to heal and prevent ulcers in the stomach (gastric ulcers) and the first part of the small intestine (duodenal ulcers). These ulcers can be caused by excessive stomach acid.
  2. Gastroesophageal Reflux Disease (GERD): Femme Tablet is used to manage the symptoms of GERD, a condition where stomach acid flows back into the esophagus, leading to symptoms like heartburn and acid regurgitation.
  3. Zollinger-Ellison Syndrome: Femme Tablet can be part of the treatment for this rare condition where the stomach produces excessive amounts of acid.
  4. Esophagitis: Femme Tablet is used to treat inflammation of the esophagus caused by stomach acid.
  5. Heartburn Relief: Femme Tablet is available over-the-counter in lower strengths to provide temporary relief from heartburn, acid indigestion, and sour stomach.
  6. Erosive Esophagitis: Femme Tablet may be used to treat erosive esophagitis, a condition characterized by severe inflammation and damage to the lining of the esophagus due to chronic acid reflux.
  7. Prevention of Stress Ulcers: In hospital settings, Femme Tablet may be used to prevent stress ulcers in critically ill patients who are at risk of developing ulcers due to factors like severe illness, trauma, or surgery.
  8. As Part of Combination Therapy: Femme Tablet is sometimes used in combination with other medications, such as antibiotics, to treat certain gastrointestinal conditions, like Helicobacter pylori infections.

Off-label Uses of Femme Tablet

  1. Allergic Reactions and Anaphylaxis: Femme Tablet may be used off-label as an adjunctive treatment for allergic reactions, including anaphylaxis. It can help reduce symptoms like hives and itching and may be administered along with other medications like epinephrine.
  2. Prevention of Aspirin-Induced Gastric Ulcers: Some individuals who need to take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) for pain or inflammation management may be prescribed Femme Tablet to reduce the risk of developing gastric ulcers or gastrointestinal bleeding.
  3. Eosinophilic Esophagitis: Femme Tablet may be used off-label in the management of eosinophilic esophagitis, a chronic immune system disease that causes inflammation of the esophagus. It can help alleviate symptoms by reducing stomach acid production.
  4. Chronic Urticaria (Hives): In some cases, Femme Tablet may be used off-label to help manage chronic urticaria (hives) that are unresponsive to other treatments. It can provide relief from symptoms such as itching and swelling.
  5. Stomach Acid Reduction During Surgery: Femme tablets may be used perioperatively (before, during, or after surgery) to reduce the risk of aspiration pneumonia or other complications in individuals undergoing certain surgical procedures.
  6. Systemic Mastocytosis: Femme Tablet may be considered off-label in the treatment of systemic mastocytosis, a rare condition characterized by an abnormal accumulation of mast cells in various tissues. It can help manage symptoms related to excess histamine release.
  7. Stress Reduction in Intensive Care Units: In some intensive care settings, Femme Tablet may be prescribed to reduce the risk of stress ulcers in critically ill patients. It can help protect the gastrointestinal lining during periods of severe illness.
  8. Treatment of Chronic Cough: Chronic cough can sometimes be associated with gastroesophageal reflux disease (GERD). Femme Tablets may be used off-label to alleviate cough symptoms related to GERD.
Femme Tablet Uses and Indications

What is Femme?

Femme is one of the leading brands of Famotidine, manufactured and marketed by Batala Pharmaceuticals, Pakistan.

Femme Tablet’s Alternatives : Other Similar Brands

The following are some alternative brands of Femme and their manufacturers.

  • Famot : Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Apsin : Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Polypep : Wilsons Pharmaceuticals, Pakistan.
  • Nocid : Novartis Pharma (Pakistan) Ltd.
  • Acicon : Barrett Hodgson Pakistan (Pvt) Ltd.
  • Optifam : Merck (Pvt) Ltd.
  • Famtaza : Zafa Pharmaceutical Laboratories (Pvt) Ltd, Pakistan.
  • Fomen : Sharooq Pharmaceuticals, Pakistan.
  • H2F : Ferozsons Laboratories Ltd, Pakistan.
  • Ulcenil : Siza International (Pvt) Ltd, Pakistan.
  • Famopsin : High-Q Pharmaceuticals (Pvt) Ltd, Pakistan.

Femme : Available Formulations and Strengths

Presently, Femme is available in tablet form.

  • Femme Tablets : 20mg and 40mg strengths.

Who Should Not Use Femme? – Contraindications

Femme tablets have certain contraindications, meaning there are situations or conditions in which the use of this medication is not recommended.

  • Hypersensitivity or Allergy: Individuals who have had a hypersensitivity reaction or allergy to Famotidine or any of the other components in the formulation should not take this medication.
  • Severe Renal Impairment (Creatinine Clearance < 10 mL/min): Femme Tablet is primarily eliminated through the kidneys. In individuals with severe kidney impairment, the clearance of the drug may be significantly reduced, potentially leading to an accumulation of the medication.
  • End-Stage Renal Disease (ESRD) Requiring Hemodialysis: Femme tablets should be used with caution in individuals with ESRD undergoing hemodialysis. Dosing may need to be adjusted based on the specific situation.
  • Porphyria: Femme Tablet may exacerbate symptoms in individuals with a rare genetic disorder called porphyria.
  • Children Under 12 Years of Age (for certain formulations): Some formulations of Femme Tablet may not be suitable for use in children under 12 years old. Always follow the specific instructions provided by the healthcare provider.
  • Use in Combination with Rilpivirine-Containing Products: Concomitant use of Femme Tablet with Rilpivirine-containing products is contraindicated due to potential interactions.

What is the Recommended Daily Dosage of Femme?

Femme Tablet Dose for Gastroesophageal Reflux Disease (GERD) and Erosive Esophagitis:

  • Adults: One tablet of 20 mg, twice daily. In some cases, a higher dose of 40 mg twice daily may be prescribed for more severe symptoms.
  • Children (12 years and older): 20 mg, once daily.

Femme Tablet Dose for Gastric Ulcers:

  • Adults: One tablet of 40 mg, once daily at bedtime.
  • Children (12 years and older): One tablet of 20 mg taken orally once daily at bedtime, or as directed by a healthcare provider.

Femme Tablet Dose for Duodenal Ulcers:

  • Adults: One tablet of 20 mg, once daily at bedtime.
  • Children (12 years and older): 20 mg, once daily at bedtime, or as directed by a healthcare provider.

Femme Tablet Dose for Zollinger-Ellison Syndrome:

  • The Initial Dose: One tablet of 20 mg, every 6 hours.
  • The dose may be adjusted based on individual response.

Femme Tablet Dose for Prevention of Recurrent Duodenal Ulcers:

  • Adults: One tablet of 20 mg, once daily at bedtime.
  • Children (12 years and older): One tablet of 20 mg, once daily at bedtime, or as directed by a healthcare provider.

Over-the-Counter (OTC) Femme Tablet Dose for Heartburn and Acid Indigestion:

  • For Temporary Relief: One tablet of 20 mg, every 12 to 24 hours as needed.
  • It should not be used for more than 14 days without consulting a healthcare provider.

How Femme Works?

Femme is a medication that belongs to a class of drugs known as H2 receptor antagonists, or H2 blockers. Its primary mode of action involves inhibiting the action of histamine on certain cells in the stomach.