Detran P Tablet Uses

Detran P is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for its analgesic (pain-relieving) and anti-inflammatory properties. The following are some common uses and indications of Detran P Tablet:

1. Pain Relief: Detran P Tablet is used to relieve pain of various origins, including musculoskeletal pain, dental pain, postoperative pain, and pain associated with conditions like arthritis.
2. Inflammatory Conditions: Detran P Tablet is used to reduce inflammation in conditions like rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and other musculoskeletal disorders. It helps alleviate symptoms like joint pain, stiffness, and swelling.
3. Dysmenorrhea (Menstrual Pain): Detran P Tablet may be used to alleviate the pain and discomfort associated with menstrual cramps.
4. Migraines: In some cases, Detran P Tablet may be used to provide relief from acute migraine headaches.
5. Postoperative Pain: Detran P Tablet is sometimes used to manage pain after surgical procedures, especially those involving musculoskeletal structures.
6. Painful Conditions Due to Inflammation or Injury: It can be used for a variety of painful conditions resulting from inflammation, such as tendonitis, bursitis, and sprains.

Off-label Uses of Detran P Tablet

1. Dental Pain: Detran P Tablet may be used off-label to provide relief from dental pain, such as toothaches or pain after dental procedures.
2. Renal Colic: In some cases, Detran P Tablet may be used to help alleviate the pain associated with kidney stones or renal colic.
3. Acute Gout Attacks: Detran P Tablet may be used off-label in the management of acute gout attacks, helping to reduce pain and inflammation.
4. Soft Tissue Injuries: It may be considered for the management of pain and inflammation associated with soft tissue injuries, such as strains and sprains.
5. Osteoarthritis in Non-Approved Joints: While diclofenac is approved for osteoarthritis in certain joints, a healthcare provider might prescribe it off-label for osteoarthritis in other joints.

Detran P is one of the leading brands of Diclofenac Potassium, manufactured and marketed by Sunshine Pharmaceuticals (Pvt.) Ltd, Pakistan.

The following are some alternative brands of Detran P and their manufacturers.

• Caflam : Novartis Pharma (Pakistan) Ltd.
• Maxit : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Diclorep : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Beflam : Batala Pharmaceuticals Pakistan.
• Diclo P : Indus Pharmaceuticals (Pvt) Ltd, Pakistan.
• Sofac-P : Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.
• Voltaflam : Platinum Pharmaceuticals (Pvt) Ltd, Pakistan.
• Artimov-K : Barrett Hodgson Pakistan (Pvt) Ltd.
• Artinil K : Global Pharmaceuticals, Pakistan.
• Klic-F : Tabros Pharma Pakistan.
• Catafen : Cibex (Pvt) Ltd, Pakistan.

Presently, Detran P is available in Tablet form.

• Detran P Tablet : 50mg and 75 mg strengths.

Detran P tablets have specific contraindications, meaning there are situations or conditions where the medication should not be used.

1. Allergy or Hypersensitivity: Individuals with a known allergy or hypersensitivity to diclofenac or other nonsteroidal anti-inflammatory drugs (NSAIDs) should not use Detran P Tablet.
2. History of Severe Allergic Reactions to NSAIDs: If a person has experienced severe allergic reactions (such as anaphylaxis) to other NSAIDs in the past, Detran P Tablet is contraindicated.
3. Active Peptic Ulcers or Gastrointestinal Bleeding: Detran P tablet can increase the risk of gastrointestinal bleeding, so it should not be used in individuals with active peptic ulcers or a history of gastrointestinal bleeding.
4. Severe Heart Failure: Detran P tablet is contraindicated in individuals with severe heart failure, as it can exacerbate the condition.
5. Severe Kidney Impairment: It should be avoided in individuals with severe kidney impairment or end-stage renal disease (ESRD) that require dialysis.
6. Severe Liver Impairment: Detran P tablet should be used with caution in individuals with severe liver disease or hepatic impairment.
7. Third Trimester of Pregnancy: Detran P tablet is contraindicated in the third trimester of pregnancy due to the potential for harm to the fetus and possible complications during delivery.
8. History of Asthma, Urticaria, or Allergic-type Reactions to Aspirin or Other NSAIDs: Individuals with a history of asthma, urticaria (hives), or other allergic-type reactions after taking aspirin or other NSAIDs should not use Detran P Tablet.
9. Hypovolemia (Low Blood Volume): Detran P tablet can lead to fluid retention and edema, so it should be used with caution or avoided in individuals with low blood volume.
10. Children Under 18: Detran P Tablet tablets are typically not recommended for use in children under 18 years old.

Detran P Tablet Dose for Pain and Inflammation:

• For Adults: One tablet of 50mg, 2 to 3 times daily.
• Your healthcare provider may adjust the dosage based on the severity of your pain and your individual response to the medication.
• The maximum daily dose is usually 200 mg, but it’s essential to follow your doctor’s recommendations closely.

Detran P Tablet Dose for Menstrual Pain (Dysmenorrhea):

• Starting Dose: One tablet of 50mg, 2 to 3 times daily at the onset of menstrual pain.
• Your healthcare provider may adjust the dose based on your pain relief needs.

Detran P Tablet Dose for Migraine:

• Used as a single Dose of 50mg tablet, at the onset of a migraine attack.
• If necessary, a second 50 mg dose may be taken after 2 hours, but do not exceed a total of 100 mg in a 24-hour period.

Detran P Tablet Dose for Ankylosing Spondylitis or Osteoarthritis:

• Starting Dose: One tablet of 50mg, 2 to 3 times daily.
• Your healthcare provider may adjust the dosage based on your specific condition.

Detran P Tablet works by inhibiting the activity of the COX enzyme. There are two forms of COX: COX-1 and COX-2. COX-1 is involved in normal bodily functions, including the protection of the stomach lining. COX-2 is primarily involved in inflammation. By inhibiting COX, Detran P tablet reduces the production of prostaglandins. This leads to a decrease in inflammation, which in turn can help alleviate pain, reduce swelling, and improve joint mobility.