Colofac Tablet Uses

Colofac tablet is a medication primarily used to relieve symptoms associated with irritable bowel syndrome (IBS) and other gastrointestinal disorders. Following are some common and off-label uses of Colofac tablets:

Common Uses Of Colofac Tablet

1. Irritable Bowel Syndrome (IBS): Colofac tablet is commonly prescribed for the treatment of IBS, a chronic condition characterized by abdominal pain, bloating, and changes in bowel habits.
2. Abdominal Pain and Cramps: Colofac tablet is used to alleviate abdominal pain and cramps associated with functional gastrointestinal disorders.
3. Spastic Colon: Colofac tablets may be used to relieve symptoms of spastic colon, which is characterized by increased muscular contractions in the colon.
4. Gastrointestinal Motility Disorders: Colofac tablets may be used in the treatment of disorders characterized by abnormal or irregular movements of the digestive tract.
5. Functional Bowel Disorders: Colofac tablet is used for functional bowel disorders where abnormal muscle contractions in the gastrointestinal tract lead to symptoms like pain and bloating.
6. Post-Gastrointestinal Surgery Symptoms: Colofac tablets may be used to alleviate symptoms such as abdominal pain and cramps following certain gastrointestinal surgical procedures.

Off-label Uses of Colofac Tablet

1. Functional Dyspepsia: Colofac tablets may be used off-label for individuals with functional dyspepsia, a condition characterized by chronic or recurrent upper abdominal discomfort or pain without an identifiable cause.
2. Gastroesophageal Reflux Disease (GERD): In some cases, Colofac tablets may be used off-label to help alleviate symptoms of GERD, such as heartburn and acid reflux.
3. Non-Ulcer Dyspepsia: Colofac tablets may be considered in the management of non-ulcer dyspepsia, a condition characterized by symptoms like bloating, early satiety, and abdominal discomfort, without an identifiable cause.
4. Post-Infectious Irritable Bowel Syndrome (PI-IBS): Colofac tablets may be considered for individuals with IBS-like symptoms that have developed after an episode of infectious gastroenteritis.
5. Colonic Diverticulitis: In some cases, Colofac tablets may be used off-label to help manage symptoms associated with colonic diverticulitis.
6. Inflammatory Bowel Disease (IBD) Symptom Management: While not a primary treatment for IBD, Colofac tablets may be used off-label to help manage symptoms like abdominal cramps and pain in individuals with Crohn’s disease or ulcerative colitis.
7. Gallbladder Disorders: Colofac tablets may be considered for the relief of symptoms associated with certain gallbladder disorders, such as biliary dyskinesia.

Colofac is one of the leading brands of Mebeverine, manufactured and marketed by Abbott Laboratories.

The following are some alternative brands of Colofac and their manufacturers.

• Zeespa : Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.
• Mevever MR : Getz Pharmaceuticals (Pvt) Ltd, Pakistan.
• Colospas : Nabiqasim Industries (Pvt) Ltd, Pakistan.
• Spasler-Neo : AGP (Pvt) Ltd, Pakistan.
• Aspa : Highnoon Laboratories Ltd, Pakistan.
• Colorest : Wilsons Pharmaceuticals, Pakistan.
• Sameb MR : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Baver : Glitz Pharma, Pakistan.
• Colonil : Genom Pharmaceuticals (Pvt) Ltd, Pakistan.
• Mibs : Shaheen Pharmaceuticals, Pakistan.

Presently, Colofac is available in Tablet form

Colofac Tablet : 135mg strength

There are certain risks associated with Using Colofac tablet which should be considered before starting treatment:

People with certain medical conditions such as heart disease or glaucoma should not use this medication without consulting their physician first.

Women who are pregnant or breastfeeding should also consult their doctor before using Colofac.

Colofac may interact with other medications, so it’s important that you inform your doctor about all medications you’re currently taking when prescribed this drug.

The long-term use of Colofac has not been studied extensively, so caution must be taken if used over an extended period of time.

Colofac Tablet Dose for Irritable Bowel Syndrome (IBS):

• One tablet (135mg), usually three times a day
  This may be adjusted based on the severity of symptoms and individual patient response.

Colofac Tablet Dose for Other Gastrointestinal Disorders:

• The recommended dosage may vary depending on the specific condition being treated and should be determined by your healthcare provider.

It is recommended to take Colofac approximately 20 minutes before a meal.

Colofac is a musculotropic antispasmodic medication, It works directly on the smooth muscle of the gastrointestinal tract. Colofac has smooth muscle-relaxant properties and acts as an inhibiting phosphodiesterase.

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