Arinac Syrup Uses

Arinac syrup is a combination medication of an antipyretic (NSAID) and a decongestant. It is primarily used for the relief of symptoms associated with fever, colds, flu, and sinus congestion. Arinac syrup is mostly recommended for children and adults where a low dose of medicine is needed. The following are some common uses of Arinac Syrup:

1. Nasal Congestion: The use of Arinac syrup helps relieve nasal congestion by shrinking the blood vessels in the nasal passages. This can provide temporary relief from a stuffy or blocked nose commonly experienced during colds and flu.
2. Sinus Pressure and Pain: Arinac syrup is used to reduce inflammation and alleviate pain associated with sinus congestion and pressure. It can help relieve headaches, facial pain, and sinus discomfort.
3. Fever and Body Aches: Arinac syrup also has antipyretic (fever-reducing) and analgesic (pain-relieving) properties. Using Arinac syrup can help reduce fever and relieve body aches and pains that often accompany colds or flu.
4. Upper Respiratory Symptoms: Arinac may help alleviate other symptoms commonly associated with upper respiratory infections, such as sore throat, cough, and general discomfort.

Off-label Uses of Arinac Syrup

1. Sinusitis: Arinac syrup may be used off-label to help relieve symptoms of sinusitis, such as sinus pressure, pain, and congestion. It can provide temporary relief by reducing inflammation and shrinking blood vessels in the nasal passages and sinuses.
2. Allergic Rhinitis: Pseudoephedrine may be used off-label to manage symptoms of allergic rhinitis, such as sneezing, nasal itching, and congestion.
3. Headaches: Arinac is sometimes used off-label for the relief of tension headaches or migraines.
4. Common Cold Symptoms: Arinac Syrup may be used off-label to relieve symptoms associated with the common cold, such as headache, nasal congestion, and sinus pressure.

Arinac syrup is one of the leading brands with the combination of Ibuprofen & Pseudoephedrine in oral liquid form, manufactured and marketed by Abbott Laboratories (Pakistan) Ltd.

The following are some available alternative brands of Arinac Syrup and their manufacturers.

• Rhinoff : Atco Laboratories Ltd, Pakistan.
• Sinurine : Fozan Pharmaceuticals Industries (Pvt) Ltd, Pakistan.
• Texcol Sinus : Raazee Therapeutics (Pvt) Ltd, Pakistan.
• Rovinac : Rock Pharmaceuticals, Pakistan.
• Fedrin : Davis Pharmaceutical Laboratories, Pakistan.
• Neonac : Neo Medix Pharma, Pakistan
• Enac : Eros Pharmaceuticals, Pakistan.

Presently, Arinac is available in Syrup and Tablet forms.

Arinac Syrup:

• Ibuprofen 100mg/5ml
• Pseudoephedrine 15mg/5ml

Arinac Tablet : Ibuprofen 200mg, Pseudoephedrine 30mg strength

Arinac Forte Tablet : Ibuprofen 400mg, Pseudoephedrine 60mg strength

Arinac syrup has specific contraindications, which are situations or conditions in which the Arinac should not be used due to potential risks or interactions.

Contraindications for Ibuprofen (an active ingredient of Arinac):

1. Allergy or hypersensitivity to ibuprofen or other NSAIDs.
2. History of asthma, bronchospasm, or allergic reactions after taking NSAIDs.
3. Active or history of peptic ulcers, gastrointestinal bleeding, or perforation.
4. Severe liver or kidney disease.
5. Bleeding disorders or taking anticoagulant medications.
6. Severe heart failure.
7. The third trimester of pregnancy.

Contraindications for Pseudoephedrine (another active ingredient of Arinac):

1. Allergy or hypersensitivity to pseudoephedrine or sympathomimetic drugs.
2. Severe coronary artery disease or coronary artery bypass graft surgery.
3. Uncontrolled high blood pressure (hypertension).
4. Severe heart disease, including irregular heart rhythms or recent heart attack.
5. Hyperthyroidism.
6. Severe kidney disease.
7. Narrow-angle glaucoma.

Arinac Syrup Dose for Adults and Children (12 years and older):

• 10 ml (2 teaspoons) every 4 to 6 hours, up to a maximum of 40 mL (8 teaspoons) within 24 hours.

Arinac Syrup Dose for Children (6-11 years):

• 5 ml (1 teaspoon) every 4 to 6 hours, up to a maximum of 20 mL (4 teaspoons) within 24 hours.

Arinac’s mode of action depends on its active ingredients.

1. Ibuprofen:
   It is a nonsteroidal anti-inflammatory drug (NSAID) that has analgesic (pain-relieving), antipyretic (fever-reducing), and anti-inflammatory properties. It works by inhibiting the production of certain chemicals in the body called prostaglandins, which are responsible for pain, inflammation, and fever. By reducing the levels of prostaglandins, ibuprofen helps alleviate pain, reduce fever, and relieve inflammation associated with conditions such as colds, flu, and sinus congestion.
2. Pseudoephedrine:
   It is a sympathomimetic decongestant. It works by constricting the blood vessels in the nasal passages and sinuses, which helps reduce swelling and congestion. By shrinking the blood vessels, pseudoephedrine helps relieve nasal congestion, allowing for easier breathing and reducing the feeling of stuffiness associated with colds, flu, and sinus congestion.

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