Nimesulide Tablet Uses

Nimesulide tablet is primarily used for short-term relief of mild to moderate pain. from arthritis, menstrual cramps, headaches, and other types of pain. It can be used alone or with other medications to reduce swelling and inflammation associated with certain conditions such as gout and tendonitis. Additionally, Nimesulide may help reduce fever in some cases.

Benefits of Using Nimesulide Tablet

• Nimesulide has several benefits including its ability to quickly reduce pain associated with various conditions without producing the same degree of side effects as other NSAIDs such as ibuprofen or aspirin.
• Additionally, Nimesulide also performs well when taken on an empty stomach without causing any gastric irritation or indigestion like some other NSAIDs do when taken with food.
• Lastly, Nimesulide is effective at reducing the risk of developing complications from certain medical conditions such as heart attacks caused by angina pectoris (chest pains).

Nimesulide is one of the leading non-steroidal anti-inflammatory (NSAIDs) drugs, Nimesulide is manufactured and marketed by

many pharmaceutical companies.

Here are some available brands of nimesulide and their manufacturers.

• Nise : Pharmevo Pakistan (Pvt) Ltd.
• Nims : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Unix : Hilton Pharmaceuticals (Pvt) Ltd.
• Modact IR : Platinum Pharmaceuticals (Pvt) Ltd, Pakistan.
• Mexidon : Searl Pakistan (Pvt) Ltd.
• Amsolide : Amson Vaccines & Pharma (Pvt) Ltd.
• Artilide : Global Pharmaceuticals, Pakistan
• Geoslide : Geofman Pharmaceuticals, Pakistan.
• Nugesic : Helix Pharma (Pvt) Ltd, Pakistan.
• Orina : Shrooq Pharmaceuticals, Pakistan.

Presently, Nimesulide is available in Tablet Form

Nimesulide Tablets : 100mg Strength

One major contraindication for Nimesulide is a history or presence of allergies or hypersensitivity reactions to NSAIDs (non-steroidal anti-inflammatory drugs).

Additionally, those with asthma should not take this medication as it can trigger an asthma attack.

Nimesulide can also interact negatively with other medications, including Warfarin and Methotrexate; therefore individuals taking these medications should consult their healthcare provider before taking medication that contains Nimesulide.

The dose of Nimesulide will depend on your condition and response to treatment but typically it should not exceed 400mg per day taken two times a day for adults over 12 years old who weigh more than 50 kg (110 lbs).

For children between 6 months and 12 years old weighing less than 50kg (110 lbs), the dosage should not exceed 2mg/kg per day divided into two doses per day not exceeding 100 mg per dose twice daily.

The mechanism by which Nimesulide works involves blocking cyclooxygenase enzymes (COX 1 and COX 2), which are responsible for producing prostaglandins – molecules responsible for promoting pain and inflammation – as well as reducing action potentials within nerve cells to reduce sensitivity levels. By blocking COX enzymes, prostaglandin synthesis is inhibited thus providing relief from painful symptoms associated with inflammatory conditions such as arthritis or muscle spasms.

In addition, reducing action potentials within sensory nerve cells results in reduced sensitivity levels thus decreasing the amount of pain experienced by the individual