Arinac Side Effects

Arinac is a combination of Ibuprofen and pseudoephedrine. It is often used to relieve symptoms like congestion, sinus pressure, and pain associated with conditions like the common cold or allergies. Arinac can have side effects, and it’s important to be aware of them. Below are some common side effects associated with the active ingredients of Arinac.

Ibuprofen Side Effects

Ibuprofen is an active ingredient of Arinac and can cause the following side effects:

1. Gastrointestinal Issues: Ibuprofen can irritate the stomach lining and may cause side effects like stomach pain, indigestion, heartburn, nausea, and even ulcers or bleeding in some cases.
2. Gastrointestinal Bleeding: In rare cases, ibuprofen can lead to gastrointestinal bleeding, manifesting as black, tarry stools or vomit that looks like coffee grounds. Seek immediate medical attention if you experience these symptoms.
3. Kidney Effects: Long-term or high-dose use of ibuprofen can harm the kidneys and lead to kidney problems, including acute kidney injury.
4. Cardiovascular Effects: There is some evidence that ibuprofen may increase the risk of heart attack or stroke, particularly in people with underlying cardiovascular conditions.
5. Allergic Reactions: Allergic reactions to ibuprofen are rare but can include hives, rash, itching, swelling, severe dizziness, and difficulty breathing. Seek immediate medical attention if you experience these symptoms.
6. Fluid Retention: Ibuprofen may cause fluid retention, leading to swelling, particularly in the legs and ankles.
7. Headache: Ironically, prolonged use of ibuprofen can sometimes lead to “rebound” headaches, where the medication’s effect wears off, and a headache returns.
8. High Blood Pressure: In some cases, ibuprofen may cause an increase in blood pressure.
9. Liver Effects: Although less common than with other pain relievers like acetaminophen, ibuprofen can affect liver function in some cases.

Pseudoephedrine Side Effects

Pseudoephedrine is another active ingredient of Arinac and can cause the following side effects:

1. Nervousness and Restlessness: Pseudoephedrine is a stimulant, and one of the most common side effects is increased nervousness, restlessness, or anxiety.
2. Insomnia: Pseudoephedrine can interfere with sleep, leading to difficulty falling or staying asleep.
3. Increased Heart Rate: This medication can cause an increase in heart rate (tachycardia) and palpitations.
4. Increased Blood Pressure: Pseudoephedrine can raise blood pressure, which may be a concern for individuals with hypertension or other cardiovascular issues.
5. Dry Mouth: Pseudoephedrine often causes dry mouth or a dry throat.
6. Dizziness: Some people may experience dizziness or lightheadedness when taking pseudoephedrine.
7. Gastrointestinal Upset: Pseudoephedrine can lead to gastrointestinal side effects like nausea and stomach discomfort.
8. Tremors or Shaking: Individuals may sometimes experience tremors or shaking hands when using pseudoephedrine.

Arinac is one of the leading brands with a combination of Ibuprofen and Pseudoephedrine, manufactured and marketed by Abbott Laboratories (Pakistan) Ltd.

Presently, Arinac is available in Tablet and Syrup Forms

Arinac Tablet : Ibuprofen 200mg, Pseudoephedrine 30mg strength

Arinac Forte Tablet : Ibuprofen 400mg, Pseudoephedrine 60mg strength

Arinac Syrup : Ibuprofen 100mg/5ml, Pseudoephedrine 15mg/5ml strength

• Monoamine Oxidase Inhibitors (MAOIs): Arinac the combination of ibuprofen & pseudoephedrine with MAOIs, a class of antidepressants, can lead to severe and potentially life-threatening reactions, including high blood pressure (hypertensive crisis).
• Blood Thinners (Anticoagulants): Arinac can increase the risk of bleeding when taken with anticoagulants like warfarin or antiplatelet drugs like aspirin. Similarly, Arinac may have a similar effect, though it’s less studied.
• Other NSAIDs: Concurrent use of multiple nonsteroidal anti-inflammatory drugs (NSAIDs) like Arinac can increase the risk of gastrointestinal bleeding and ulcers.
• Corticosteroids: Taking Arinac with corticosteroids, like prednisone, can increase the risk of stomach irritation and ulcers.
• High Blood Pressure Medications: Arinac can raise blood pressure, so using it with high blood pressure medications may reduce the effectiveness of those medications or lead to an increase in blood pressure.
• Beta-Blockers: Beta-blockers, commonly used for high blood pressure and heart conditions, may reduce the effectiveness of Arinac in relieving nasal congestion.
• Antidepressants: Some antidepressants, particularly tricyclic antidepressants (TCAs), can increase the risk of side effects like increased blood pressure and heart rate when used with Arinac.
• Diuretics (Water Pills): Arinac can reduce the effectiveness of diuretics and lead to elevated blood pressure.
• Lithium: Arinac can increase lithium levels in the blood, potentially leading to lithium toxicity. If you’re taking lithium, consult your healthcare provider before using ibuprofen.
• Methotrexate: Arinac can decrease the elimination of methotrexate, potentially increasing its toxicity.
• ACE Inhibitors: Arinac may reduce the effectiveness of ACE inhibitors used for high blood pressure and heart failure.
• Certain Heart Medications: Some medications used for heart conditions, such as digoxin, may be affected by Arinac. Consult your healthcare provider for guidance.
• Alcohol: Arinac the combination of ibuprofen and pseudoephedrine can irritate the stomach lining. Drinking alcohol while taking these medications can increase the risk of stomach irritation and bleeding.