Neuxam Tablet Uses

Neuxam tablet is primarily used for the treatment of anxiety and panic disorders. It belongs to the benzodiazepine class also known as an anxiolytic drug. Following are some common and off-label uses of Neuxam Tablet:

Common Uses of Neuxam Tablet

1. Anxiety Disorders: Neuxam tablet is commonly used for the management of generalized anxiety disorder (GAD), which is characterized by excessive worry and tension. It may also be prescribed for other anxiety disorders, such as social anxiety disorder and specific phobias.
2. Panic Disorder: Neuxam tablet is also used for the treatment of panic disorder, which involves recurrent and unexpected panic attacks. It can help reduce the frequency and severity of panic attacks and alleviate associated symptoms.
3. Anxiety Associated with Depression: Neuxam tablets may be used in combination with antidepressant medications to manage anxiety symptoms that occur in conjunction with depression.

Off-label Uses of Neuxam Tablet

1. Sleep Disorders: Neuxam tablets may be used off-label to manage sleep disorders, particularly insomnia. It can help promote sleep initiation and reduce anxiety-related sleep disturbances.
2. Adjustment Disorder: Neuxam tablets may be used for the short-term management of adjustment disorder, which involves emotional and behavioral symptoms in response to a stressful event or life change. It can help alleviate anxiety and distress associated with the adjustment process.
3. Essential Tremor: Neuxam tablets may be used to manage essential tremor, a neurological disorder characterized by involuntary shaking. It can help reduce the severity of tremors and improve overall function.
4. Axiety-Associated Irritable Bowel Syndrome (IBS): Neuxam tablet is also used to manage symptoms of IBS, such as abdominal pain, bloating, and diarrhea or constipation. It can help alleviate anxiety-related symptoms and potentially improve overall well-being in individuals with IBS.

Neuxam is one of the leading brands of Alprazolam, manufactured and marketed by Standpham Pakistan (Pvt) Ltd.

Below are some available similar brands that can be used as an alternative to Neuxam:

• ALP : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Xanax : Pfizer Laboratories Inc.
• Paraz : Getz Pharmaceuticals (Pvt) Ltd, Pakistan.
• Azolam : Matrin Dow Pharma, Pakistan.
• Hilaxin : Himont Pharmaceuticals (Pvt) Ltd, Pakistan.
• Pralzo : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Neram : Genuix Pharmaceuticals (Pvt) Ltd, Pakistan.
• Xylepam : Brookes Pharmaceutical Laboratories (Pvt) Ltd, Pakistan.
• Pinix : Adamjee Pharmaceuticals (Pvt) Ltd, Pakistan.
• Zenith : Ferozsons Laboratories Ltd, Pakistan.

Presently, Neuxam is available in Tablet Form with the following strengths.

Neuxam Tablet : 0.25mg, 0.5mg, and 1mg strengths.

Neuxam has several contraindications, which are specific situations or conditions in which the use of Neuxam is not recommended due to the potential risks outweighing the benefits.

Hypersensitivity: Neuxam is contraindicated in individuals who have a known hypersensitivity or allergy to Neuxam or other benzodiazepines. Allergic reactions can range from mild to severe and may include rash, itching, swelling, or difficulty breathing.

Acute narrow-angle glaucoma: Neuxam is contraindicated in individuals with acute narrow-angle glaucoma, a condition characterized by increased pressure in the eye. Neuxam can further increase eye pressure and worsen the condition.

Severe respiratory insufficiency: Neuxam is contraindicated in individuals with severe respiratory insufficiency, as it may further depress the respiratory system and impair breathing.

Myasthenia gravis: Neuxam is contraindicated in individuals with myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue. Neuxam can exacerbate muscle weakness and impair muscle function.

Severe hepatic impairment: Neuxam is contraindicated in individuals with severe hepatic impairment, as it may impair the metabolism and clearance of the medication, leading to increased drug levels and potential toxicity.

Pregnancy and breast-feeding: Neuxam is generally contraindicated during pregnancy and breastfeeding due to potential risks to the fetus or infant. It can cross the placenta and be excreted in breast milk, which may lead to adverse effects.

Neuxam Dose for Anxiety Disorders:

• • Adults: One tablet of 0.25mg or 0.5mg, three times a day. The dose may be increased gradually as needed and tolerated.
  • Elderly or debilitated patients: Starting dose, one tablet of 0.25mg, two to three times a day.

Neuxam Dose for Panic Disorder:

• • Adults: One tablet of 0.5mg, three times a day. The dose may be increased gradually as needed and tolerated.
  • Elderly or debilitated patients: Starting dose, One tablet of 0.25mg, two to three times a day.

Neuxam works by binding to specific receptors in the brain called GABA-A receptors. By binding to the GABA-A receptors, alprazolam enhances the inhibitory effects of GABA, resulting in an increased flow of chloride ions into the neurons. This leads to an overall reduction in neuronal excitability and can produce sedative, anxiolytic (anti-anxiety), muscle relaxant, and anticonvulsant effects.

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