Tercica Side Effects

Tercica, a nonsteroidal anti-inflammatory drug (NSAID), shares many side effects with other NSAIDs. Tercica can have various side effects, some of which are more common than others. It’s important to note that not everyone experiences these side effects, and their severity can vary from person to person health conditions. Here are some common and less common side effects associated with Tercica use.

Common Side Effects

• Gastrointestinal Effects: Tercica can irritate the stomach lining, leading to symptoms like heartburn, nausea, stomach pain, and in some cases, ulcers or gastrointestinal bleeding.
• Dizziness or Headache: Some individuals may experience dizziness or headaches while taking Tercica.
• Fluid Retention: NSAIDs can cause fluid retention, leading to swelling in the legs, ankles, or hands.
• Hypertension: In some cases, Tercica may elevate blood pressure, particularly in individuals with pre-existing hypertension.
• Rash or Skin Reactions: Allergic reactions to Tercica can manifest as skin rashes, itching, or hives.
• Renal Effects: NSAIDs, including Tercica, can affect kidney function. This might present as changes in urination patterns or kidney function abnormalities.
• Liver Issues: Rarely, Tercica can cause liver problems, indicated by symptoms such as yellowing of the skin or eyes (jaundice), dark urine, or persistent abdominal pain.
• Asthma Exacerbation: Some individuals may experience worsening asthma symptoms when taking NSAIDs like Tercica.
• Bleeding Issues: NSAIDs can interfere with blood clotting, leading to increased bleeding or bruising, especially in individuals with bleeding disorders.
• Tinnitus: Tercica might rarely cause ringing in the ears (tinnitus) or other auditory issues.
• Cardiovascular Effects: Prolonged use of NSAIDs might slightly increase the risk of heart attack or stroke, particularly in individuals with pre-existing cardiovascular conditions.

Less Common Side Effects

• Severe Allergic Reactions: In rare cases, Tercica can trigger severe allergic reactions known as anaphylaxis, characterized by symptoms like difficulty breathing, chest tightness, swelling of the face, lips, tongue, or throat, and a severe skin rash.
• Gastrointestinal Issues: Less common but potentially severe gastrointestinal effects can occur, such as perforation (formation of holes) in the stomach or intestines, which can lead to severe abdominal pain, vomiting blood, or black, tarry stools.
• Serious Skin Reactions: Although uncommon, Tercica can cause severe skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis, characterized by blistering, peeling, and severe skin rash accompanied by fever.
• Liver Toxicity: In rare instances, Tercica can cause severe liver damage leading to symptoms like abdominal pain, yellowing of the skin or eyes (jaundice), dark urine, and fatigue.
• Blood Disorders: Tercica may rarely affect blood cell production, resulting in conditions like thrombocytopenia (low platelet count) or leukopenia (low white blood cell count).
• Vision or Eye Issues: Some individuals might experience blurred vision or other vision disturbances as a less common side effect of Tercica.
• Psychiatric Reactions: Rarely, NSAIDs like Tercica might cause mood changes or depression in certain individuals.
• Renal Impairment: In some cases, Tercica may lead to renal impairment or kidney failure, especially in individuals with pre-existing kidney conditions.
• Hypersensitivity Reactions: Tercica can cause hypersensitivity reactions other than anaphylaxis, such as angioedema (rapid swelling beneath the skin) or bronchospasm (constriction of the airways).

Tercica is one of the leading brands of Dexibuprofen, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

1. Other NSAIDs: Concurrent use of multiple NSAIDs (e.g., aspirin, ibuprofen, naproxen) with Tercica can increase the risk of gastrointestinal bleeding and ulcers.
2. Anticoagulants and Antiplatelet Drugs: Tercica can potentiate the effects of anticoagulants (e.g., warfarin) and antiplatelet drugs (e.g., clopidogrel), increasing the risk of bleeding.
3. Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Combining Tercica with SSRIs or SNRIs can increase the risk of bleeding, especially gastrointestinal bleeding.
4. ACE Inhibitors and Angiotensin II Receptor Blockers (ARBs): Taking Tercica along with ACE inhibitors or ARBs can reduce the effectiveness of these medications and may lead to decreased kidney function.
5. Diuretics: Tercica may reduce the effectiveness of diuretics (water pills) and may affect blood pressure control when used concurrently.
6. Methotrexate: Concurrent use of methotrexate and Tercica can increase methotrexate levels in the blood, potentially leading to toxicity. This combination can also increase the risk of methotrexate-induced kidney damage.
7. Lithium: Tercica can increase lithium levels in the blood, potentially leading to lithium toxicity.
8. Corticosteroids: Concurrent use of corticosteroids with Tercica can increase the risk of gastrointestinal ulceration or bleeding.
9. Cyclosporine: Tercica can increase the risk of kidney damage when used along with cyclosporine.
10. Certain Antihypertensive Medications: Tercica might reduce the efficacy of some antihypertensive medications, potentially leading to increased blood pressure.