Intig-D Side Effects

Intig-D is Ossein Mineral Complex (OMC) and Vitamin D3 combination medication is often used as a dietary supplement to support bone health. This combination typically includes essential minerals such as calcium, phosphorus, and magnesium, along with Vitamin D3 (cholecalciferol), which aids in calcium absorption and bone health. Here are common and less common side effects associated with Intig-D.

Common Side Effects

• Gastrointestinal Upset: Many people may experience gastrointestinal side effects when taking Intig-D. These can include constipation, diarrhea, bloating, or gas.
• Kidney Stones: In some cases, high-dose Intig-D, especially when taken without adequate fluid intake, can increase the risk of developing kidney stones. This is more common in individuals with a history of kidney stones or those who are prone to them.

Less Common Side Effects

• Hypercalcemia: High doses of Intig-D can lead to hypercalcemia, a condition characterized by elevated levels of calcium in the blood. Symptoms may include nausea, vomiting, frequent urination, muscle weakness, and confusion.
• Allergic Reactions: Although rare, some individuals may experience an allergic reaction to components of the Intig-D, such as additives or fillers. Allergic reactions can manifest as skin rashes, itching, swelling, or difficulty breathing.
• Vitamin D Toxicity: A high dose of Intig-D can lead to Vitamin D toxicity (hypervitaminosis D). Symptoms may include nausea, vomiting, weakness, and elevated levels of calcium in the blood. It is essential to adhere to the recommended daily dosage of Intig-D.
• Electrolyte Imbalance: In rare cases, Intig-D can lead to electrolyte imbalances, which may cause muscle weakness, irregular heartbeats, or other symptoms.

Intig-D is one of the leading brands of Ossein Mineral Complex (OMC) + Vitamin D3, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

Presently, Intig-D is available in Tablet and Suspension Forms.

Intig-D Tablet : Ossein Mineral Complex 830mg and Vitamin D 400 I.U strengths.

1. Calcium Channel Blockers: Intig-D which contains calcium, can potentially interfere with the effectiveness of calcium channel blockers, a class of medications used to treat conditions like high blood pressure and certain heart conditions. To avoid this interaction, take cIntig-D at least 2 hours apart from calcium channel blockers.
2. Bisphosphonates: Bisphosphonates, used to treat osteoporosis, can have their absorption reduced when taken with Intig-D. It is generally recommended to take Intig-D at a different time of day than bisphosphonates to ensure proper absorption.
3. Levothyroxine:  Intig-D can interfere with the absorption of levothyroxine, a medication used to treat thyroid conditions. To prevent this interaction, it’s advisable to take levothyroxine on an empty stomach and Intig-D at a different time.
4. Corticosteroids: Long-term use of corticosteroid medications may decrease bone density, and Intig-D may be recommended. However, it’s essential to coordinate the use of Intig-D with your healthcare provider to ensure proper dosing and avoid infection.
5. Antacids: Some antacids contain calcium and may lead to an excessive intake of calcium when used in combination with Intig-D. If you are taking antacids and Intig-D, discuss the dosage and timing with your healthcare provider to avoid excessive calcium intake.
6. Orlistat: Orlistat is a weight loss medication, that may decrease the absorption of fat-soluble vitamins like Vitamin D. If you are taking Orlistat, consult with your healthcare provider to ensure you are getting adequate Intig-D.
7. Medications that Affect Mineral Metabolism: Medications that affect mineral metabolism such as certain diuretics or antiepileptic drugs, may alter the body’s handling of calcium, magnesium, and phosphorus. Your healthcare provider can help manage these interactions.
8. Vitamin D Toxicity: High-dose or prolonged use of Intig-D can lead to Vitamin D toxicity, so it’s important to be cautious when using Intig-D in combination with OMC. Ensure you do not exceed the recommended daily dose without your healthcare provider’s guidance.