Froben Side Effects

Froben is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation. Like all medications, it can have both common and less common side effects. It’s important to use this medication under the guidance of a healthcare professional and follow the prescribed dosage. Here are some common and less common side effects of Froben.

Common Side Effects:

• Gastrointestinal Issues: Gastrointestinal side effects are relatively common with NSAIDs, including Froben. These can include stomach pain, heartburn, indigestion, nausea, vomiting, and diarrhea.
• Headache: Some individuals may experience headaches while taking Froben.
• Dizziness: Dizziness is another possible side effect, though it is relatively common.
• Skin Reactions: Skin rash or itching can occur in some cases.
• Elevated Blood Pressure: Froben can lead to an increase in blood pressure in some individuals.
• Edema (Swelling): Swelling, particularly in the extremities (hands and feet), is a potential side effect.

Less Common Side Effects:

• Gastrointestinal Ulcers and Bleeding: Although less common, NSAIDs like Froben can cause gastrointestinal ulcers and bleeding, which can be serious. Symptoms may include black, tarry stools or vomiting blood.
• Kidney Problems: Froben can affect kidney function, and in rare cases, it may lead to kidney damage.
• Liver Function: Rarely, Froben may affect liver function, leading to abnormal liver enzyme levels.
• Blood Disorders: Less commonly, Froben can lead to blood disorders such as anemia, leukopenia (reduced white blood cell count), or thrombocytopenia (reduced platelet count).
• Cardiovascular Effects: In rare cases, NSAIDs like Froben can increase the risk of heart-related issues, including heart attack or stroke.
• Allergic Reactions: Severe allergic reactions are rare but can occur, leading to symptoms like swelling of the face or throat, difficulty breathing, and hives.
• Vision Changes: Vision disturbances, such as blurred vision, are uncommon but possible.
• Neurological Symptoms: Some individuals may experience nervous system-related side effects, like confusion, hallucinations, or seizures, although these are relatively rare.

Froben is one of the leading brands of Flurbiprofen, manufactured and marketed by Abbott Laboratories, Pakistan.

Presently, Froben is available in Tablet Form

Froben Tablets : 50mg and 100mg Strengths

1. Other NSAIDs: Combining Froben with other NSAIDs (such as ibuprofen or naproxen) can increase the risk of side effects, including gastrointestinal issues and bleeding.
2. Antiplatelet Drugs: Froben may interfere with the antiplatelet effects of drugs like aspirin, which can affect their ability to prevent blood clots.
3. Anticoagulants (Blood Thinners): Froben may increase the risk of bleeding when used with anticoagulants like warfarin, heparin, or direct oral anticoagulants.
4. Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Combining Froben with these classes of antidepressant medications can increase the risk of gastrointestinal bleeding.
5. Corticosteroids: Taking Froben with corticosteroids like prednisone can increase the risk of gastrointestinal bleeding and other side effects.
6. Angiotensin-converting enzyme (ACE) Inhibitors and Angiotensin Receptor Blockers (ARBs): Froben may reduce the effectiveness of these blood pressure medications and potentially increase blood pressure.
7. Diuretics: Diuretics may reduce the effectiveness of Froben and increase the risk of kidney problems.
8. Lithium: Froben may increase lithium levels in the blood, potentially leading to lithium toxicity.
9. Methotrexate: The concurrent use of Froben and methotrexate, a medication used for various conditions, can increase the risk of methotrexate toxicity.
10. Cyclosporine and Tacrolimus: Froben can increase the risk of kidney damage when used with these immunosuppressant medications.
11. Mifepristone: Concomitant use of Froben with mifepristone (used for medical abortion) can reduce the effectiveness of mifepristone.
12. Probenecid: Probenecid may increase the concentration of Froben in the blood, potentially leading to an increased risk of side effects.
13. Phenytoin: Froben may affect the metabolism of phenytoin, an antiepileptic drug, potentially altering its effectiveness.
14. Quinolone Antibiotics: Concurrent use of Froben with certain quinolone antibiotics can increase the risk of seizures.