Colofac Side Effects

Colofac is a medication commonly used to treat gastrointestinal disorders such as irritable bowel syndrome (IBS) and other conditions that cause abdominal pain and discomfort. Like all medications, it can potentially cause side effects in some individuals. Here are some of the possible side effects associated with Colofac.

Common Side Effects

• Headache
• Dizziness
• Nausea
• Vomiting
• Abdominal pain or cramps
• Diarrhea

Less Common Side Effects

• Fatigue
• Skin rash or itching
• Dry mouth
• Blurred vision
• Constipation
• Allergic reactions (rare but potentially serious; seek medical attention immediately if you experience symptoms such as difficulty breathing, swelling of the face or throat, or severe skin reactions)

Colofac is one of the leading brands of Mebeverine, manufactured and marketed by Abbott Laboratories

Presently, Colofac is available in Tablet form

Colofac Tablet : 135mg strength

Anticholinergic Medications: Colofac has anticholinergic effects, so taking it alongside other medications with anticholinergic properties can increase the risk of side effects such as dry mouth, blurred vision, and constipation. Examples of anticholinergic drugs include certain antihistamines, tricyclic antidepressants, and some antipsychotic medications.

Grapefruit Juice: Grapefruit juice can inhibit the metabolism of the drug in the body, potentially leading to increased levels of the medication in the bloodstream. This could increase the risk of side effects. It’s advisable to avoid consuming grapefruit or grapefruit juice while taking Colofac.

CYP3A4 Inhibitors: Drugs that inhibit the enzyme CYP3A4 can affect the drug’s metabolism and potentially increase its concentration in the blood. Some common CYP3A4 inhibitors include ketoconazole, itraconazole, clarithromycin, and ritonavir.

Other Medications: Always inform your healthcare provider about all the medications, including prescription, over-the-counter, herbal supplements, and dietary supplements you are taking. Some drugs may interact with Colofac by affecting its metabolism or having similar gastrointestinal effects.