ST Mom Tablet Uses

ST Mom tablet is a medication that is used for its therapeutic effects on the uterus and stomach. It is primarily used for the prevention and treatment of gastric ulcers. Following are some common and off-label uses of ST Mom Tablet:

Common Uses of ST Mom Tablet

1. Induction of Labor: ST Mom tablet is commonly used to induce labor in pregnant women, particularly in cases where there is a medical need to initiate or augment the labor process.
2. Medical Abortion: ST Mom tablet in combination with another medication called mifepristone, is used for medical abortion in early pregnancy. It helps to induce the termination of pregnancy by causing uterine contractions and the expulsion of the uterine contents.
3. Postpartum Hemorrhage Prevention and Treatment: ST Mom tablet can be used to prevent and treat postpartum hemorrhage, a potentially life-threatening complication following childbirth. It helps to promote uterine contractions and reduce bleeding.
4. Gastrointestinal Conditions: In addition to gastric ulcer prevention and treatment, ST Mom tablets may be used to manage other gastrointestinal conditions, such as prevention of non-steroidal anti-inflammatory drug (NSAID)-induced ulcers, treatment of NSAID-associated gastrointestinal adverse effects, and management of certain types of diarrhea.

Off-label Uses of ST Mom Tablet

1. Management of Missed Miscarriage: ST Mom tablets may be used off-label to manage missed miscarriage, a condition where a nonviable pregnancy remains in the uterus. It can help induce uterine contractions and facilitate the expulsion of the pregnancy tissue.
2. Medical Management of Ectopic Pregnancy: In certain cases, ST Mom tablets may be used as a non-surgical treatment option for early ectopic pregnancy (a pregnancy that occurs outside the uterus). It is typically used in combination with the medication methotrexate.
3. Cervical priming before surgical procedures: ST Mom tablets may be used for cervical priming before certain surgical procedures involving the cervix or uterus, such as dilation and curettage (D&C) or hysteroscopy.

ST Mom is one of the leading brands of Misoprostol, manufactured and marketed by Zafa Pharmaceutical Laboratories (Pvt) Ltd, Pakistan.

The following are some alternative brands of ST Mom and their manufacturers.

• Breeky : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Cytotol : Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.
• Cytotec : Pfizer Laboratories Inc.
• Prosotec : Atco Laboratories (Pvt) Ltd, Pakistan.
• Mite : Genix Pharmaceuticals (Pvt) Ltd, Pakistan.
• Cyotec : Biogen Pharma, Pakistan.
• Miso : Global Pharmaceuticals, Pakistan.
• Zivus : Wilshire Laboratories (Pvt) Ltd, Pakistan.

Presently, ST Mom is available in Tablet Form with the following strengths.

ST Mom Tablets : 25mcg and 200mcg strengths.

ST Mom has several contraindications, and its use should be avoided in the following situations:

Hypersensitivity or allergy: ST Mom should not be used in individuals who have a known hypersensitivity or allergy to ST Mom or any of its components. Allergic reactions can range from mild skin rashes to severe anaphylaxis.

Pregnancy: ST Mom is contraindicated during pregnancy, particularly in the second and third trimesters, unless it is being used for medical abortion under specific circumstances and with appropriate medical supervision. It can cause uterine contractions, which may lead to miscarriage or preterm labor.

Women of childbearing potential not using effective contraception: ST Mom should not be used in women of childbearing potential who are not using effective contraception, as it can cause fetal harm if pregnancy occurs.

Active cardiovascular disease: ST Mom should be used with caution in individuals with active cardiovascular disease or a history of cardiovascular events, as it may increase the risk of cardiovascular complications.

Inflammatory bowel disease: ST Mom is contraindicated in individuals with inflammatory bowel disease (such as Crohn’s disease or ulcerative colitis) due to the potential exacerbation of symptoms.

Severe hepatic impairment: ST Mom should be used with caution in individuals with severe hepatic impairment, as it may affect liver function and metabolism.

ST Mom tablet Dose for Prevention and treatment of gastric ulcers caused by NSAIDs:

• • 1 – 2 tablets of 200mcg, taken orally four times a day with meals and at bedtime.
  • The dosage may be adjusted based on individual response and tolerability, under the guidance of a healthcare professional.

ST Mom tablet Dose for Medical abortion:

• • 4 tablets of 200mcg, taken orally or inserted vaginally.
  • The dosage regimen and timing may vary, and it should be followed as prescribed by a healthcare professional.

ST Mom tablet Dose for Cervical ripening (off-label use):

• • 1 – 2 tablets of 25mcg, inserted vaginally, with repeat doses administered at specified intervals.
  • The recommended dose for cervical ripening varies depending on the specific indication and the healthcare provider’s preference.

ST Mom is a synthetic prostaglandin E1 analog that exerts its pharmacological effects by interacting with specific receptors in the body. ST Mom tablet works by binding to and activating prostaglandin receptors, particularly the EP3 receptor subtype, which is found in various tissues, including the stomach, intestines, uterus, and cervix.

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