Spiromide Tablet Uses

Spiromide tablet is used to reduce the amount of fluid in the body and increase urine output. It is a potassium-sparing diuretic medication. The following are some common and off-label uses of Spiromide tablets:

Common Uses of Spiromide Tablet

1. Congestive Heart Failure: Spiromide tablets may be used to treat edema associated with congestive heart failure, a condition where the heart is unable to pump blood effectively, leading to a buildup of fluid in the body.
2. Liver Cirrhosis: Spiromide tablets may also be used to treat edema associated with liver cirrhosis. In this condition, the liver becomes damaged and unable to function correctly, leading to fluid buildup in the abdomen (ascites) and legs.
3. Kidney Disease: Spiromide tablets may be used to treat edema associated with kidney disease, a condition where the kidneys are unable to filter waste products from the blood effectively, leading to a buildup of fluid in the body.
4. Hypertension: In some cases, Spiromide tablets may also be used to treat hypertension (high blood pressure), particularly in patients with fluid retention who have not responded well to other medications.
5. Nephrotic Syndrome: Spiromide tablet is sometimes used in the treatment of nephrotic syndrome which causes proteinuria, a kidney disorder characterized by high levels of protein in the urine, low levels of protein in the blood, and swelling (edema) in the body.

Off-label Uses of Spiromide Tablet

1. Polycystic Ovary Syndrome (PCOS): Spiromide tablets may be used off-label to treat the symptoms of PCOS, a condition that causes hormonal imbalances, irregular periods, and acne.
2. Hirsutism: Spiromide tablets may be used to treat hirsutism, a condition where women develop excessive hair growth on the face, chest, and back.
3. Lymphedema: Spiromide tablets may also be used to treat lymphedema, a condition where there is a buildup of lymphatic fluid in the tissues, causing swelling and discomfort.

Spiromide is one of the leading brands of Spironolactone BP and Furosemide PH, manufactured and marketed by Searle Pharma Pakistan.

Presently, Spiromide is available in Tablets Form

Spiromide-20 Tablet : Spironolactone 50mg + Furosemide 20mg strengths.

Spiromide-40 Tablet : Spironolactone 50mg + Furosemide 40mg strengths.

Despite the potential benefits of Spiromide uses discussed above, there are several contraindications that must be taken into consideration before beginning a course of treatment.

Hypersensitivity: Patients who are hypersensitive or allergic to Spirommide or its ingredients (Spironolactone and Furosemide) should not use it.

Anuria: Patients who have anuria, which is a condition where the kidneys are unable to produce urine, should not use Spiromide.

Hyperkalemia: Patients who have hyperkalemia, a condition characterized by high levels of potassium in the blood, should not use Spiromide.

Hyponatremia: Patients who have hyponatremia, a condition characterized by low levels of sodium in the blood, should not use Spiromide.

Severe renal impairment: Patients with severe renal impairment, which is a condition where the kidneys are not functioning properly, should not use Spiromide.

Addison’s disease: Patients with Addison’s disease, a condition where the adrenal glands do not produce enough hormones, should not use Spiromide.

Pregnancy and breast-feeding: Spiromide should not be used during pregnancy or breastfeeding unless recommended by a healthcare professional.

The usual dose of Spiromide is 1-4 tablets of Spiromide-20 or 1-2 tablets of Spiromide-40 equally divided over 24 hours.

It’s important to use Spiromide exactly as directed by your doctor.

The mode of action of Spiromide depends on its active ingredients, they have their separate mode of action.

Spironolactone BP (an active ingredient of Spiromide) works by interfering with the hormones that control salt and water levels in the body, thus leading to increased urine output and reduced fluid retention.

Furosemide PH (another active ingredient of Spiromide) is an additional type of diuretic that works by blocking sodium reabsorption in your kidneys which increases urine production resulting in decreased fluid levels throughout your body.

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