Silliver Tablet Uses

Silliver tablets are used to treat and support liver health. It has antioxidant and anti-inflammatory properties that can help to protect the liver from damage.

The following are some common uses and indications of Silliver Tablet

1. Liver Health: Silliver tablet is most well-known for its potential to support liver health. It is believed to have antioxidant and anti-inflammatory properties that may help protect liver cells from damage and promote their regeneration. It is often used as a complementary therapy for various liver conditions, including hepatitis, cirrhosis, and non-alcoholic fatty liver disease (NAFLD).
2. Detoxification: Silliver tablet is thought to enhance the liver’s detoxification processes by promoting the production of enzymes involved in the removal of toxins from the body.
3. Antioxidant Properties: The use of Silliver tablet provides antioxidant properties that can help neutralize harmful free radicals in the body. This can be beneficial for overall health and may also play a role in protecting the liver from oxidative stress.
4. Cholesterol Management: Some studies suggest that Silliver tablets may have a positive effect on cholesterol levels, particularly by lowering LDL (bad) cholesterol and triglycerides.
5. Gallbladder Health: Silliver tablets may help improve gallbladder function and reduce the risk of gallstones.
6. Diabetes Support: Silliver tablets may help improve blood sugar control in individuals with type 2 diabetes, though more studies are needed to confirm these effects.

Off-label Uses of Silliver Tablet

1. Alcohol-Related Liver Disease: Silliver tablets can be used as a potential treatment for alcohol-related liver disease, including alcoholic hepatitis and alcoholic cirrhosis. It is believed to have protective effects on the liver, although results from studies are mixed, and more research is needed.
2. Chemotherapy-Induced Liver Toxicity: Some cancer patients receiving chemotherapy may experience liver toxicity as a side effect. Silliver tablet has been used to reduce chemotherapy-induced liver damage. However, research in this area is ongoing.
3. Hepatitis C: Silliver tablet has been explored as a supplement to support liver health in individuals with hepatitis C. It may have a modest positive impact on liver enzyme levels, but it is not a primary treatment for hepatitis C.
4. Gastrointestinal Disorders: Silliver tablet is used off-label to alleviate symptoms of various gastrointestinal disorders, such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). While it may have some anti-inflammatory effects, its role in managing these conditions is not well-established.
5. Neurological Disorders: Silliver tablet has neuroprotective properties and the potential to help manage conditions like Alzheimer’s disease and Parkinson’s disease. However, these studies are in the early stages, and more research is needed.
6. Antioxidant and Anti-Inflammatory Effects: Silliver tablet’s antioxidant and anti-inflammatory properties have led to investigations into its potential use in conditions involving oxidative stress and inflammation, such as rheumatoid arthritis and certain skin disorders.

Silliver is one of the leading brands of Silymarin, manufactured and marketed by Abbott Laboratories.

The following are some alternative brands of Silliver and their manufacturers.

• SYM : Getz Pharmaceuticals (Pvt) Ltd, Pakistan.
• Silymax : Sharooq Pharmaceuticals, Pakistan.
• Equadin : Wilsons Pharmaceuticals, Pakistan.
• Silchol : Atco Laboratories Ltd, Pakistan.
• Silimarin : Amson Vaccines & Pharma (Pvt) Ltd, Pakistan.
• Silirin : Akson Pharmaceuticals (Pvt) Ltd, Pakistan.
• Symac : Mcolson Research Laboratories, Pakistan.
• Hepamyrin : Qintar Pharmaceuticals, Pakistan.
• Hepar : Fynk Pharmaceuticals, Pakistan.
• Hepasil : Helicon Pharmaceutek Pakistan (Pvt) Ltd.

Presently, Silliver is available in Tablet and Syrup forms.

Silliver Tablet : 200mg strength.

Silliver Syrup : 105mg/5ml strength.

Silliver tablets are generally considered safe when used as directed and at appropriate doses, but there are certain contraindications and precautions that individuals should be aware of before using Silliver tablets.

1. Allergy or Sensitivity: Individuals who have known allergies to milk thistle, or Silymarin, or should avoid Silliver tablets.
2. Pregnancy and Breastfeeding: There is limited research on the safety of Silliver tablets during pregnancy and breastfeeding, so it is generally recommended to avoid its use during these periods to err on the side of caution.
3. Children: Silliver tablets are typically designed for adult use, and their safety and efficacy in children have not been well studied. Consult a healthcare professional before giving a Silliver tablet to a child.
4. Certain Medical Conditions: Silliver tablets may interact with certain medical conditions. It’s important to exercise caution or avoid its use if you have:
   Hormone-sensitive conditions, such as breast, uterine, or ovarian cancer, such as Silliver tablets may have estrogenic effects.
   Gallstones or a history of gallbladder issues, as Silliver tablets can stimulate bile production.
   Allergy to ragweed or related plants, as cross-reactivity is possible.
   Diabetes or low blood sugar (hypoglycemia), as Silliver tablets may affect blood sugar levels.
   Liver transplant or other major liver surgery, as Silliver tablet may interfere with immunosuppressive medications.
5. Surgery: If you are scheduled for surgery, it’s important to inform your healthcare provider about your use of Silliver tablets, as it may be recommended to discontinue use before the procedure due to potential effects on blood clotting and liver function.

Silliver Tablet Dose for Liver Health Maintenance:

• One tablet of 200mg, per day may be sufficient.

Silliver Tablet Dose for Specific Liver Conditions:

• (Hepatitis or Fatty Liver Disease)
• One tablet of 200mg, twice or thrice a day.
• However, it’s essential to consult with a healthcare provider for personalized guidance.

Silliver tablet contains Silymarin, it is an active compound found in milk thistle (Silybum marianum), and is believed to exert its effects on the liver through several mechanisms of action:

• Antioxidant Properties: Silymarin is a potent antioxidant, meaning it can neutralize harmful molecules called free radicals in the body. These free radicals can damage cells, including liver cells, and contribute to various liver diseases. By scavenging free radicals, silymarin helps protect liver cells from oxidative stress.
• Anti-Inflammatory Effects: Silymarin has anti-inflammatory properties that can reduce inflammation in the liver. Chronic inflammation is often associated with liver diseases such as hepatitis and cirrhosis. By reducing inflammation, silymarin may help mitigate liver damage.
• Cell Membrane Stabilization: Silymarin is thought to stabilize the outer membranes of liver cells. This can make it more difficult for toxins to enter the cells and cause damage.
• Enhancement of Glutathione: Silymarin can increase the levels of an important antioxidant called glutathione in the liver. Glutathione plays a crucial role in detoxifying harmful substances in the liver.
• Stimulation of Liver Regeneration: Silymarin may stimulate the regeneration of liver cells, allowing damaged liver tissue to heal and repair more quickly.
• Inhibition of Fibrosis: Fibrosis is the formation of scar tissue in the liver, which can lead to cirrhosis. Silymarin has been studied for its potential to inhibit the development of liver fibrosis.
• Detoxification Support: Silymarin may enhance the liver’s detoxification processes by promoting the production of enzymes involved in the removal of toxins from the body.