Qbal Tablet Uses

Qbal tablet is used to provide vitamin b12, which plays a crucial role in various bodily functions, particularly in the nervous system.

The following are some common uses and indications of Qbal Tablet

1. Vitamin B12 Deficiency: Qbal tablets are primarily used to treat and prevent vitamin B12 deficiency. This deficiency can occur due to various factors, including poor diet, certain medical conditions, and medications that interfere with B12 absorption.
2. Pernicious Anemia: It is a type of anemia caused by a deficiency of intrinsic factor, a protein that helps the body absorb vitamin B12. Qbal tablet is used to treat pernicious anemia.
3. Neuropathy: Qbal tablet is often used in the treatment of peripheral neuropathy, a condition characterized by numbness, tingling, and weakness in the extremities. It is especially beneficial in neuropathy caused by vitamin B12 deficiency.
4. Diabetic Neuropathy: Qbal tablets may be prescribed for individuals with diabetic neuropathy, a type of nerve damage that can occur in people with diabetes.
5. Alcoholic Neuropathy: Chronic alcohol consumption can lead to vitamin B12 deficiency and subsequent neuropathy. Qbal may be used to address this condition.
6. Nerve Regeneration: Qbal is believed to play a role in promoting nerve regeneration and function. It can be used to support the recovery of damaged nerves.
7. Homocysteine Reduction: Qbal, along with other B vitamins, helps lower homocysteine levels in the blood. Elevated homocysteine levels are associated with an increased risk of cardiovascular disease.

Off-label Uses of Qbal Tablet

1. Multiple Sclerosis (MS): Qbal tablets are used off-label in individuals with multiple sclerosis. It is believed to have a neuroprotective effect that may be beneficial in managing certain symptoms.
2. Peripheral Neuropathy Due to Chemotherapy: Qbal tablet has been studied for its potential to alleviate peripheral neuropathy, a common side effect of certain chemotherapy drugs.
3. Amyotrophic Lateral Sclerosis (ALS): There is limited research suggesting that Qbal tablets may have a neuroprotective effect in individuals with ALS. However, more studies are needed to establish its efficacy.
4. Chronic Pain Management: Qbal tablet, due to its potential nerve-regenerating properties, may be used in the management of chronic pain conditions associated with nerve damage.
5. Fibromyalgia: Some healthcare providers may consider Qbal tablet as part of a treatment regimen for fibromyalgia, a condition characterized by widespread musculoskeletal pain and fatigue.
6. Macular Degeneration: Some studies have explored the use of Qbal tablets in combination with other vitamins for age-related macular degeneration, a condition affecting central vision.
7. Restless Leg Syndrome (RLS): There is limited evidence to suggest that Qbal tablets may be beneficial in managing symptoms of restless leg syndrome.
8. Depressive Disorders: Using Qbal tablets plays a role in improving mood and depressive symptoms, particularly in individuals with comorbid B12 deficiency.
9. Cognitive Decline and Dementia: There is some research suggesting that vitamin B12, may play a role in cognitive function. Qbal tablets may be considered in the management of cognitive decline, although more research is needed.

Qbal is one of the leading brands of Mecobalamin, manufactured and marketed by Bosch Pharmaceuticals (Pvt) Ltd, Pakistan.

The following are some alternative brands of Qbal and their manufacturers.

• Methycobal : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Cobolmin : Mecter International, Pakistan.
• Neuromet : Merck Serono Pharmaceutical.
• Mecobal : NabiQasim Pharmaceuticals, Pakistan.
• Mabil : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Mecogen : Genetics Pharmaceuticals, Pakistan.
• Nervon : Getz Pharmaceuticals (Pvt) Ltd, Pakistan
• Bezel : Saffron Pharmaceuticals, Pakistan.
• Incobal : Indus Pharmaceuticals, Pakistan.
• Elgin : Novartis, Pakistan.
• Mylaxzon : Barrett Hodgson Pharmaceuticals, Pakistan.

Presently, Qbal is available in Tablet and Injection forms.

Qbal Tablet : 500mcg strength.

Qbal Injection : 500mcg/ml strength.

Qbal is generally considered safe and well-tolerated when used as directed. However, there are certain situations in which its use may not be recommended due to potential risks or interactions.

1. Hypersensitivity: Individuals with known hypersensitivity or allergy to Mecobalamin or any of its components should avoid Qbal use.
2. Polycythemia Vera: Qbal tablet may exacerbate erythropoiesis (red blood cell production) in individuals with polycythemia vera, a condition characterized by an excess of red blood cells.
3. Leber’s Disease: Qbal tablet should be used with caution, if at all, in individuals with Leber’s hereditary optic neuropathy, a rare genetic disorder that can lead to vision loss.
4. Cobalt or Cyanide Allergy: Some forms of vitamin B12 contain trace amounts of cobalt, and in rare cases, individuals with specific allergies to cobalt or related compounds may have an adverse reaction.
5. Megaloblastic Anemia Not Due to Vitamin B12 Deficiency: If the megaloblastic anemia is not due to a vitamin B12 deficiency, Qbal tablets may not be the appropriate treatment.
6. Interactions with Certain Medications: Qbal tablets may interact with certain medications, such as chloramphenicol, colchicine, proton pump inhibitors (PPIs), and some anticonvulsants. It’s important to consult a healthcare provider if taking these or other medications.
7. Pernicious Anemia Without Concurrent Intrinsic Factor Replacement: In cases of pernicious anemia (a type of anemia caused by a deficiency of intrinsic factor), the Qbal tablet may not be effective unless accompanied by intrinsic factor replacement.

Qbal Tablet Dose for Vitamin B12 Deficiency:

• One tablet of 500mcg, three times a day

Qbal Tablet Dose for Diabetic Neuropathy:

• One tablet of 500mcg, twice or thrice a day

Qbal Tablet Dose for Neuralgia:

• One tablet of 500mcg, once or twice a day

Qbal Tablet Dose for Fibromyalgia:

• One tablet of 500mcg, once or twice a day

Qbal Tablet Dose for Age-related macular degeneration:

• One tablet of 500mcg, once or twice a day

Qbal Tablet Dose for Alzheimer’s Disease:

• One tablet of 500mcg, once or twice a day

Qbal tablet contains an active form of vitamin B12 (Mecobalamin) that acts as a cofactor for two important enzymes: methionine synthase and L-methylmalonyl-CoA mutase.

Methionine synthase is involved in the conversion of homocysteine to methionine. Homocysteine is a toxic amino acid that can damage blood vessels and increase the risk of heart disease and stroke. Methionine is an essential amino acid that is used to build proteins and other important molecules.

L-methylmalonyl-CoA mutase is involved in the breakdown of fats and proteins. It converts L-methylmalonyl-CoA to succinyl-CoA, which is a key intermediate in the citric acid cycle. The citric acid cycle is the main energy-producing pathway in the body.