Provate-G Cream Uses

Provate-G cream is a combination medication used topically to treat certain skin conditions that involve inflammation, itching, and potential bacterial infections. The following are some common uses and indications of Provate-G Cream:

1. Inflammatory Skin Conditions: The use of Provate-G cream helps to reduce inflammation, redness, itching, and swelling associated with various skin conditions. It works by suppressing the immune response that leads to inflammation.
2. Bacterial Skin Infections: Provate-G cream is used to treat or prevent bacterial infections of the skin. It is effective against a wide range of bacteria and is used to prevent or treat secondary bacterial infections that can occur when the skin is compromised due to inflammation or other factors.

Some specific skin conditions that may be treated with Provate-G cream include:

• Eczema: This chronic skin condition causes itching, redness, and inflammation. Provate-G cream can help manage these symptoms and prevent bacterial infections that might develop due to scratching.
• Dermatitis: Various forms of dermatitis, such as contact dermatitis or seborrheic dermatitis, can lead to skin inflammation and discomfort. Using Provate-G cream can provide relief from symptoms and help prevent bacterial infections.
• Psoriasis: Psoriasis is characterized by red, scaly patches on the skin. The use of Provate-G cream can help reduce the inflammation associated with psoriasis.
• Skin Allergies: Skin allergies, like allergic reactions to plants or substances, can cause itching, redness, and inflammation. Provate-G cream can help alleviate these symptoms.
• Infected Skin Lesions: When skin lesions become infected with bacteria, Provate-G cream can help address both the inflammation and the infection.

Off-label Uses of Provate-G Cream

1. Acne: Provate-G cream can help to reduce inflammation and redness associated with acne. It also can help to kill bacteria that may be contributing to the acne.
2. Impetigo: It is a bacterial skin infection that causes red, crusty sores. Provate-G cream can help to reduce inflammation, and itching, by killing the bacteria.
3. Folliculitis: It is a common skin infection that causes small, red bumps on the skin. Provate-G cream can be used to reduce inflammation and itching.
4. Lichen Simplex Chronicus: It is a chronic skin condition that causes itching and inflammation. Provate-G cream is used off-label for such conditions.
5. Intertrigo: It is a type of skin rash that occurs in skin folds, such as the armpits, groin, and under the breasts. Provate-G cream is also used off-label to treat intertrigo.
6. Superficial Skin Wounds: Provate-G cream may be used off-label to treat or prevent superficial wounds (minor cuts or abrasions) that are at risk of infection or inflammation.

Provate-G is one of the leading brands of Betamethasone + Gentamicin, manufactured and marketed by Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.

The following are Some alternative brands of Provate-G Cream and their manufacturers.

• Betagenic : Atco Laboratories (Pvt) Ltd, Pakistan.
• Encore G : Reko Pharmacal (Pvt) Ltd, Pakistan.
• Effigenta : Pharma Health Pakistan (Pvt) Ltd.
• Digent : Xenon Pharmaceuticals (Pvt) Ltd, Pakistan.
• Diprocort-G : Pearl Pharmaceuticals, Pakistan.
• Lotricort-G : Dermagen Pharma, Pakistan.
• Betagent : Valor Pharmaceuticals, Pakistan.
• Mysoderm : AGP (Pvt) Ltd, Pakistan.
• Procort-G : Shrooq Pharmaceuticals, Pakistan.
• Astagent : Bloom Pharmaceuticals (Pvt) Ltd, Pakistan.
• Betawis-G : Caraway Pharmaceuticals, Pakistan.
• Genbet : Global Pharmaceuticals, Pakistan.

Presently, Provate-G is available in Cream and Ointment forms.

Provate-G Cream:

• Betamethasone Dripopionate: 0.05% w/w
• Gentamicin Sulphate: 0.1% w/w

Provate-G Ointment:

• Betamethasone Dripopionate: 0.05% w/w
• Gentamicin Sulphate: 0.1% w/w

There are specific situations and conditions in which the use of Provate-G cream is contraindicated due to potential risks or interactions.

1. Hypersensitivity or Allergy: Individuals who are hypersensitive or allergic to betamethasone, gentamicin, or any other ingredients in Provate-G cream should avoid using it.
2. Viral Skin Infections: The use of Provate-G cream can potentially worsen viral skin infections such as herpes simplex (cold sores) or varicella zoster (chickenpox). Using the cream in these cases can lead to the spread of the infection.
3. Fungal Skin Infections: Fungal skin infections, such as athlete’s foot (tinea pedis) or ringworm, should not be treated with Provate-G cream, as it can exacerbate these infections or mask their symptoms.
4. Tuberculosis (TB) Infections: Provate-G cream can suppress the immune response and potentially worsen systemic infections like tuberculosis. The use of such creams is generally avoided in individuals with active TB or those with a history of TB exposure.
5. Perioral Dermatitis: The use of Provate-G cream can exacerbate perioral dermatitis, a facial rash typically located around the mouth.
6. Rosacea: Provate-G cream should be used cautiously in individuals with rosacea, a chronic skin condition characterized by facial redness and visible blood vessels.
7. Skin Atrophy: Long-term use of corticosteroids can lead to skin thinning and atrophy. The use of Provate-G cream should be avoided in areas of the skin prone to thinning.
8. Eye Area: Provate-G cream should be avoided in the eye area, as the use of corticosteroids near the eyes can lead to serious eye conditions.
9. Children and Infants: Provate-G cream may not be suitable for use in children, especially infants, as their skin is more susceptible to corticosteroid-induced side effects.
10. Open Wounds: Provate-G cream should not be applied to open wounds, as it may slow down the wound healing process.

Provate-G Cream apply topically twice a day for 7-10

Here are the steps on how to apply Provate-G cream:

• Wash your hands thoroughly with soap and water.
• Dry the affected area of the skin.
• Apply a thin layer of cream to the affected area.
• Rub the cream in gently until it is absorbed.
• Avoid using excessive amounts of cream.
• After applying avoid covering the affected area.
• Wash your hands again after applying the cream.

Provate-G is a combination medication that contains two active ingredients: betamethasone dipropionate and gentamicin sulfate. Betamethasone dipropionate is a corticosteroid that helps to reduce inflammation and itching. Gentamicin sulfate is an antibiotic that helps to kill bacteria.

1. Betamethasone dipropionate works by binding to the glucocorticoid receptor in the skin. This receptor then activates a series of genes that lead to the production of anti-inflammatory proteins.
2. Gentamicin sulfate works by binding to the ribosomes of bacteria. This prevents the bacteria from producing proteins, which is essential for their survival.