Prevent Tablet Uses

Prevent tablet is an antibiotic medication primarily used to treat various types of bacterial and parasitic infections.

Bacterial Infections:

• Bacterial Vaginosis: Prevent tablet is used to treat bacterial vaginosis, a common vaginal infection caused by an overgrowth of certain types of bacteria in the vagina.
• Trichomoniasis: It is effective in treating trichomoniasis, a sexually transmitted infection (STI) caused by the protozoan parasite Trichomonas vaginalis.
• Giardiasis: Prevent tablet is used to treat giardiasis, an intestinal infection caused by the parasite Giardia lamblia.
• Amebiasis: Prevent tablet can be prescribed for amebiasis, an intestinal infection caused by the amoeba parasite Entamoeba histolytica.

Helicobacter pylori Eradication: Prevent tablets may be used in combination with other antibiotics to treat infections caused by the bacterium Helicobacter pylori, which can lead to conditions like peptic ulcers.

Prevention of Infections in Certain Surgical Procedures: In some cases, Prevent tablets may be used to prevent infections in patients undergoing certain surgical procedures, particularly those involving the gastrointestinal tract.

Off-label Uses of Prevent Tablet

1. Bacterial Infections Not Specifically Indicated: In some cases, a healthcare provider may use Prevent tablets to treat bacterial infections not listed in the official indications, based on their clinical judgment and assessment.
2. Prophylaxis for Certain Surgical Procedures: Prevent tablets may be used off-label as a prophylactic treatment to prevent post-operative infections for specific surgical procedures.
3. Lyme Disease: Some studies have explored the use of Prevent tablets for the treatment of Lyme disease, particularly for persistent or chronic cases. It is sometimes used as an alternative to other antibiotics like doxycycline or amoxicillin.
4. Chronic Bacterial Prostatitis: Prevent tablet may be used off-label in the treatment of chronic bacterial prostatitis, a condition characterized by recurrent urinary tract infections in men.
5. Bacterial Gastroenteritis: In certain cases, Prevent tablet may be considered for the treatment of bacterial gastroenteritis caused by susceptible organisms.
6. Clostridium difficile Infection (CDI): Prevent tablet has been explored as a potential treatment for Clostridium difficile infections, although it is not considered a first-line option.
7. Intra-abdominal Infections: Prevent tablets may be used off-label in the treatment of certain intra-abdominal infections.

Prevent is one of the leading brands of Tinidazole, manufactured and marketed by Platinum Pharmaceuticals (Pvt) Ltd, Pakistan.

The following are some alternative brands of Prevent and their manufacturers.

• Fasigyn : Pfizer Laboratories Inc.
• Trichogin : Chiesi Pharmaceuticals (Pvt) Ltd, Pakistan.
• Tindamax : Hiranis Pharmaceuticals (Pvt) Ltd, Pakistan.
• Physijin : Pharmawise Labs. (Pvt) Ltd, Pakistan.
• Tergynan : Highnoon Laboratories Ltd, Pakistan.
• Tinidazole : Siza International (Pvt) Ltd, Pakistan.

Presently, Prevent is available in Tablet form.

Prevent Tablet : 1gm strength.

Prevent tablets have specific contraindications, which are situations or conditions in which the medication should not be used due to potential harm or ineffectiveness.

1. Hypersensitivity: Individuals who have a known hypersensitivity or allergy to Tinidazole or any of its components should not take Prevent tablets.
2. First Trimester of Pregnancy: Prevent tablet is generally contraindicated during the first trimester of pregnancy due to potential risks to the developing fetus. It should only be used if the benefits outweigh the risks and under the guidance of a healthcare provider.
3. Breastfeeding: Prevent tablets can pass into breast milk, and its safety during breastfeeding has not been established. It is generally recommended to avoid its use while breastfeeding.
4. Alcohol and Within 3 Days After Stopping Alcohol Consumption: Prevent tablet may cause a disulfiram-like reaction when taken with alcohol. This reaction can include symptoms like severe nausea, vomiting, abdominal cramps, headache, and flushing. Therefore, alcohol should be avoided during Prevent tablet treatment and for at least three days after stopping the medication.
5. Blood Dyscrasias: Prevent tablets that may affect blood cell counts. It is contraindicated in individuals with blood disorders such as leukopenia (low white blood cell count), neutropenia (low neutrophil count), and thrombocytopenia (low platelet count).
6. Central Nervous System (CNS) Diseases: Prevent tablets should be used with caution or avoided in individuals with a history of or current CNS disorders, as it may exacerbate neurological symptoms.
7. Severe Hepatic Impairment: Prevent tablets should be used with caution in individuals with severe liver impairment, and it is contraindicated in those with acute liver disease.
8. Children Under 3 Years of Age: Safety and efficacy of Prevent tablet in children under 3 years of age have not been established.

Prevent Tablet Dose for Bacterial Vaginosis:

• Adults: A single 2-gram (2 tablets of Prevent 1gm) dose.
• In some cases, healthcare providers may prescribe One tablet of 1gm (1000 mg), once daily for 2 days.

Prevent Tablet Dose for Trichomoniasis:

• Adults: A single 2-gram (2 tablets of Prevent 1gm) dose.
• Sexual Partners: In cases of trichomoniasis, sexual partners should also be treated, even if they do not have symptoms.

Prevent Tablet Dose for Giardiasis:

• Adults: A single 2-gram (2 tablets of Prevent 1gm) dose.

Prevent Tablet Dose for Amebiasis:

• Adults: Two tablets of 1gm daily for 3 days.
• The usual dosage for amebiasis may involve a course of treatment that can range from 3 to 7 days.
• Children: Dosage for children is typically based on body weight, and a healthcare provider will determine the appropriate dose.

A Prevent Tablet contains Tinidazole, which is a nitroimidazole antibiotic that has a broad spectrum of activity against anaerobic bacteria and protozoa. It works by disrupting the DNA of the bacteria and parasites, which prevents them from reproducing and kills them.