Pentoxol M Tablet Uses

Pentoxol M tablet is primarily used for the treatment of various neurological disorders. It is a combination of anti-depressant and anti-psychotic drugs that provide anxiolytic and mood-stabilizing effects in individuals who suffer from Anxiety and Depression. Following are some common uses of Pentoxol M Tablet:

1. Depression: Pentoxol M tablet is commonly used for individuals experiencing moderate to severe depression. Using Pentoxol M tablets helps regulate mood and reduce depressive symptoms.
2. Anxiety Disorders: The use of Pentoxol M tablets can also be effective in treating certain anxiety disorders, such as generalized anxiety disorder (GAD) and panic disorder. Pentoxol M can help alleviate anxiety symptoms and promote a sense of calm.
3. Mood Disorders: Pentoxol M tablets may be used to manage various mood disorders, including bipolar disorder. Using Pentoxol M can help stabilize mood swings manage manic episodes and address depressive symptoms that often occur in bipolar disorder.
4. Psychotic Depression: It is a severe form of depression that involves the presence of psychotic symptoms, such as delusions or hallucinations. Pentoxol M tablets can be beneficial in treating this condition by reducing both the depressive symptoms and the associated psychosis.
5. Neuropathic Pain: In some cases, Pentoxol M tablets may be used to manage neuropathic pain, which is caused by damage to the nerves. Using Pentoxol M also provides analgesic effects that alleviate pain and improve the patient’s overall well-being.

Off-label Uses of Pentoxol M Tablet

1. Adjustment Disorders: In certain cases, Pntoxol M tablets may be used off-label to manage adjustment disorders, which are characterized by emotional and behavioral symptoms in response to a stressful life event or situation.
2. Sleep Disorders: Pentoxol M tablets may be used in the treatment of sleep disorders, such as insomnia. However, other medications specifically indicated for sleep disorders are generally preferred.
3. Pain Management: In some instances, healthcare professionals may consider Pentoxol M tablets for pain management, particularly in chronic pain conditions where depression and anxiety are comorbid factors.

Pentoxol M is one of the leading brands of Flupentixol and Melitracen, manufactured and marketed by Scotmann Pharmaceuticals, Pakistan.

The following are some alternative brands of Pentoxol M and their manufacturers.

• Deanxit : Lundbeck Pakistan (Pvt) Ltd.
• Leanxit : Acme Laboratories Pakistan (Pvt) Ltd.

Presently, Pentoxol M is available in Tablet Form in the following strength.

Pentoxol M Tablet : Flupenthixol HCl 0.5mg and Melitracen HCl 10mg strengths

Pentoxol M has several contraindications, which are conditions or circumstances that make the use of this medication inappropriate or potentially harmful.

Hypersensitivity: Individuals who have a known hypersensitivity or allergic reaction to any components of the medication should not take Pentoxol M.

Concomitant Use of Monoamine Oxidase Inhibitors (MAOIs): Pentoxol M should not be used in combination with or within two weeks of discontinuing treatment with MAOIs. The combination can lead to serious and potentially life-threatening reactions, such as serotonin syndrome.

Severe Liver or Kidney Impairment: Pentoxol M should be used with caution or avoided in individuals with severe liver or kidney impairment. These conditions can affect the metabolism and elimination of the medication from the body.

Cardiovascular Disorders: The medication should be used cautiously in individuals with cardiovascular disorders, such as a history of heart attack, heart failure, arrhythmias, or unstable angina.

Blood Disorders: Pentoxol M may worsen certain blood disorders, such as bone marrow suppression or blood dyscrasias. Therefore, it should be used with caution or avoided in individuals with pre-existing blood disorders.

Epilepsy: The medication should be used cautiously in individuals with epilepsy or a history of seizures, as it may lower the seizure threshold.

Glaucoma: Pentoxol M should be used with caution in individuals with glaucoma, as it can increase intraocular pressure.

Pentoxol M Dose: The typical recommended starting dose for adults is one tablet per day.

The dosage may be adjusted based on the individual’s response and tolerability, but it is usually not recommended to exceed three tablets per day.

Pentoxol M is a combination medication that exerts its therapeutic effects through the actions of its two active ingredients.

1. Flupentixol: It is an antipsychotic medication that belongs to the class of drugs known as thioxanthenes. It works by blocking certain receptors in the brain, particularly dopamine receptors. By inhibiting dopamine activity, flupentixol helps to regulate the transmission of neural signals, which can alleviate symptoms of psychosis.
2. Melitracen: It is a tricyclic antidepressant (TCA) that acts by inhibiting the reuptake of certain neurotransmitters, primarily serotonin and norepinephrine. By blocking the reuptake of these neurotransmitters, melitracen increases their availability in the synaptic cleft, prolonging their effects and enhancing neurotransmission.

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