Pedrol Tablet Uses

Pedrol tablet belongs to the class of medications known as analgesics and antipyretics. It is an over-the-counter medication that is primarily used to treat mild-to-moderate pain and fever reduce. Following are some common uses of Pedrol Tablet:

1. Pain Relief: Pedrol tablet is commonly used to relieve mild to moderate pain. It can effectively alleviate various types of pain, including headaches, toothaches, muscle aches, backaches, menstrual cramps, and general body aches. It is considered an effective option for pain management, especially for those who cannot tolerate or prefer to avoid non-steroidal anti-inflammatory drugs (NSAIDs).
2. Fever Reduction: Pedrol tablet is also used to reduce fever associated with various conditions, such as infections, flu, common colds, and other illnesses. It helps lower elevated body temperature and provides relief from fever-related discomfort.

Off-label Uses of Pedrol Tablet

1. Postoperative Pain: Pedrol tablet is used off-label to manage pain following surgical procedures, either alone or in combination with other pain medications.
2. Osteoarthritis: Pedrol tablet may be used for the relief of pain associated with osteoarthritis, a degenerative joint disease. However, the efficacy of Pedrol in this condition is still a subject of debate.
3. Migraine: In some cases, Pedrol tablet may be used off-label as part of the treatment regimen for migraines, particularly in combination with other migraine-specific medications.
4. Palliative Care: Pedrol tablets can be used for pain relief in individuals receiving palliative care, which focuses on providing comfort and symptom management for patients with advanced illnesses.
5. Neonatal Pain Management: Pedrol tablet may be used off-label for pain relief in neonates (newborn infants) undergoing minor procedures or experiencing pain associated with medical conditions. However, its use in this population requires careful monitoring and supervision by healthcare professionals.

Pedrol is one of the famous brands of Paracetamol, manufactured and marketed by Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.

Following are some alternative brands of Pedrol and their manufacturers.

• Panadol : GlaxoSmithKline (GSK)
• Calpol : GlaxoSmithKline (GSK)
• Febrol : Barrett Hodgson Pakistan (Pvt) Ltd.
• Disprol : Reckitt Benckiser Ltd.
• Provas : Sami Pharmaceuticals, Pakistan.
• Pedrol : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Boschtamol : Bosch Pharmaceuticals (Pvt) Ltd
• Doliprane : Sanofi Aventis (Pakistan) Ltd.
• Fevamol : Swiss Pharmaceuticals (Pvt) Ltd
• Megapol : Mega Pharmaceuticals, Pakistan.
• Panaram : Efroze Chemical Industries (Pvt) Ltd, Pakistan.

Presently, Pedrol is available in Tablet, Suspension, and Drops Forms with the following strengths.

Pedrol Tablet : 500mg strength.

Pedrol Suspension : 120mg/5ml strength.

Pedrol Drops : 60mg/5ml strength.

Pedrol has a few contraindications, which are situations or conditions in which the use of Pedrol is not recommended due to potential risks.

• Allergy or hypersensitivity: Pedrol should not be used in individuals who have a known allergy or hypersensitivity to Pedrol or any other components of the medication. Allergic reactions can range from mild skin rash to severe anaphylaxis, which is a life-threatening allergic reaction.
• Severe liver disease: Pedrol is primarily metabolized by the liver. Individuals with severe liver disease or active liver problems should use Pedrol with caution or avoid it altogether. Pedrol can potentially worsen liver function or cause further damage in these individuals.
• Alcoholism: Chronic alcohol consumption and alcoholism can increase the risk of liver damage when combined with Pedrol use. It is important to exercise caution and follow the recommended dosage guidelines when using Pedrol if you have a history of alcoholism or regular alcohol consumption.
• G6PD deficiency: Pedrol may not be suitable for individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic disorder that affects red blood cells. In some cases, Pedrol can cause hemolysis (destruction of red blood cells) in individuals with this condition.
• Pre-existing liver or kidney disease: Individuals with pre-existing liver or kidney disease should use Pedrol with caution. Reduced liver or kidney function can affect the metabolism and elimination of Pedrol from the body, potentially leading to increased drug levels and toxicity.

1. Pedrol Dose for Adults (including elderly):
   • 1 to 2 Tablets, taken every 4 to 6 hours as needed.
   • The maximum daily dose should not exceed 4000 mg (4 grams) in a 24-hour period.
   • It’s important to allow at least 4 hours between each dose and not exceed the maximum dose or frequency.
2. Pedrol Dose for Children:
   • The recommended dose for children is based on their weight. It is typically around 10 to 15 mg per kilogram of body weight per dose.
   • The dose should be given every 4 to 6 hours as needed, but not more than 4 doses in 24 hours.
   • The specific recommended dose for children can vary, so it’s best to consult with a healthcare professional or refer to the dosage instructions provided on pediatric formulations.

Pedrol works by inhibiting the synthesis of prostaglandins, which are chemical messengers that play a role in pain perception and the regulation of body temperature. By reducing the production of prostaglandins in the central nervous system, Pedrol helps to alleviate pain and reduce fever.