Panadol Tablet Uses

Panadol table is primarily used to treat painful conditions and to reduce fever. It is an analgesic drug with antipyretic properties. Following are some common uses of Panadol Tablet:

1. Pain Relief: Panadol tablet is used to treat mild to moderate pain, including headaches, toothaches, muscular aches, backaches, and pain associated with conditions such as osteoarthritis or rheumatoid arthritis.
2. Fever Reduction: Panadol tablet is also used for the reduction of fever associated with various conditions, including viral or bacterial infections, and other illnesses.
3. Postoperative Pain: Panadol tablets may be used as part of a multimodal approach to managing postoperative pain, particularly for mild to moderate pain relief in combination with other analgesics.
4. Menstrual Pain: Panadol tablet can be used for the relief of menstrual pain and discomfort, helping to alleviate cramps and improve overall well-being during the menstrual cycle.
5. Pain and Fever Associated with Vaccinations: Panadol is often recommended to manage pain and fever following vaccinations, particularly in children. It can help reduce post-vaccination discomfort and fever.
6. Cold and Flu Symptoms: Panadol tablet can also be used to relieve symptoms associated with colds and flu, such as fever, headache, sore throat, and body aches. However, it does not treat the underlying viral infection.
7. COVID-19 Post-Vaccination Discomfort: Panadol tablet is often recommended to manage post-vaccination discomforts, such as fever or injection site pain, after receiving vaccines like influenza or COVID-19 vaccines.

Off-label Uses of Panadol Tablet

1. Migraine: Panadol tablets may be used off-label for the relief of mild to moderate migraine headaches. It is often used in combination with other migraine medications and therapies.
2. Cancer-related Pain: Panadol tablets may be used as an adjunctive therapy for mild to moderate pain in cancer patients. It is often used in combination with other analgesics to provide a multimodal approach to pain management.

Panadol is one of the leading brands of Paracetamol, manufactured and marketed by GSK Pharma Pakistan.

Following are some alternative brands of Panadol and their manufacturers.

• Calpol : GlaxoSmithKline (GSK).
• Febrol : Barrett Hodgson Pakistan (Pvt) Ltd.
• Disprol : Reckitt Benckiser Ltd.
• Pedrol : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Provas : Sami Pharmaceuticals, Pakistan.
• Pedrol : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Boschtamol : Bosch Pharmaceuticals (Pvt) Ltd
• Doliprane : Sanofi Aventis (Pakistan) Ltd.
• Fevamol : Swiss Pharmaceuticals (Pvt) Ltd
• Megapol : Mega Pharmaceuticals, Pakistan.
• Panaram : Efroze Chemical Industries (Pvt) Ltd, Pakistan.

Presently, Panadol is available in Tablet, Drops, and Suspension Forms

Panadol Tablet : 500mg Strength

Panadol Drops : 60mg/5ml

Panadol Suspension : 120mg/5ml

Panadol should not be taken under the following conditions:

1. People with an allergy or hypersensitivity to Panadol or other ingredients of the drug.

2. Children below 16 years of age who have viral infections such as chickenpox, flu, etc.

3. Patients with impaired renal function and liver disease.

4. Patients taking certain medications such as warfarin, phenytoin (Dilantin), and carbamazepine.

(Tegretol), barbiturates, rifampicin (Rifadin), or trimethoprim (Bactrim).

5. Pregnant women should consult their doctor before taking Panadol as its effects during pregnancy are still unknown.

6. Panadol should never be combined with other medications containing paracetamol without consulting a healthcare professional first due to an increased risk of overdose and liver damage if taken together in excessive amounts.

Panadol Tablets Dose for Adults:

• 1 – 2 tablets every 4 – 6 hours as needed.
• The maximum daily dose should not exceed 8g per day.

Panadol Suspension Dose for Children:

• The dosing of paracetamol for children is based on their weight.
• Typically 10 to 15 mg per kg of body weight, given every 4 to 6 hours as needed.

Panadol acts by blocking the production of prostaglandins which are chemicals that mediate inflammation within the body and cause pain signals to be sent to the brain when released in large quantities.

Panadol also reduces fever by affecting hypothalamic thermoregulatory centers, causing vasodilation that leads to increased heat loss from peripheral vessels of skin tissue. This results in decreased body temperature while simultaneously reducing inflammation associated with fever symptoms like headache and muscle aches.

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