Olanzia Tablet Uses

Olanzia tablet is a medication that belongs to a class of drugs known as atypical antipsychotics. It is used to treat various mental health conditions.

The following are some common uses and indications of Olanzia Tablet:

1. Schizophrenia: Olanzia tablet is used for the treatment of schizophrenia, a severe mental disorder characterized by distorted thinking, hallucinations, delusions, and impaired emotional responsiveness.
2. Bipolar Disorder (Manic or Mixed Episodes): Olanzia tablet is used in combination with other medications to treat manic or mixed episodes associated with bipolar disorder. These episodes involve symptoms like high energy, elevated mood, impulsivity, and irritability.
3. Bipolar Disorder (Maintenance Therapy): Olanzia tablet may also be used as a maintenance treatment for individuals with bipolar disorder to help stabilize mood and prevent future episodes.
4. Depression (Adjunctive Treatment): In some cases, Olanzia tablet may be used alongside an antidepressant for individuals with treatment-resistant depression. This is known as adjunctive therapy.
5. Agitation Associated with Schizophrenia and Bipolar Disorder: Olanzia tablet may be used to manage severe agitation and aggressive behavior in individuals with schizophrenia or bipolar disorder.
6. Tourette’s Disorder: Olanzia tablet may be used to help manage the tics and associated symptoms of Tourette’s disorder, a neurological condition characterized by involuntary repetitive movements and vocalizations (tics).

Off-label Uses of Olanzia Tablet

1. Anxiety Disorders: In some cases, Olanzia tablets may be used off-label to help manage severe anxiety or anxiety-related symptoms, particularly in cases where other treatments have not been effective.
2. Post-Traumatic Stress Disorder (PTSD): Olanzia tablet has been used off-label for the treatment of certain symptoms associated with PTSD, such as flashbacks, nightmares, and hyperarousal.
3. Obsessive-Compulsive Disorder (OCD): Olanzia tablet has been explored as an adjunctive treatment for individuals with treatment-resistant OCD. It may be used in combination with other medications.
4. Major Depressive Disorder (MDD): In some cases, the Olanzia tablet may be used as an adjunctive treatment for individuals with severe, treatment-resistant depression. This is typically done in combination with an antidepressant.
5. Eating Disorders: Olanzia tablet may be considered in the treatment of certain eating disorders, such as anorexia nervosa, particularly in cases where weight restoration is challenging.
6. Insomnia: Olanzia tablet has been studied for its sedative effects and may be used off-label in some cases to help individuals with insomnia.
7. Treatment of Delirium: Olanzia tablet may be used in the management of delirium, a state of acute confusion and disorientation often seen in hospitalized patients. It may help control agitation and improve comfort.
8. Borderline Personality Disorder (BPD): Olanzia tablet may be considered as an adjunctive treatment for certain symptoms associated with borderline personality disorder, such as impulsivity and mood instability.
9. Autism Spectrum Disorder (ASD): Olanzia tablet has been explored as a potential treatment for some symptoms associated with ASD, such as irritability and aggression. However, its use in this context is still under investigation.

Olanzia is one of the leading brands of Olanzapine, manufactured and marketed by Werrick Pharmaceuticals, Pakistan.

The following are some alternative brands of Olanzia and their manufacturers.

• Zyprexa : Eli Lilly Pakistan (Pvt) Ltd.
• Olepra : Genetics Pharmaceuticals, Pakistan.
• Obsolute : Xenon Pharmaceuticals (Pvt) Ltd, Pakistan.
• Olanzin : Rasco Pharma, Pakistan.
• Lepinza : Organic Pharmaceuticals, Pakistan.
• Amprexa : Amarant Pharmaceuticals (Pvt) Ltd, Pakistan.
• Olanco : Genom Pharmaceuticals (Pvt) Ltd, Pakistan.
• Zanzia : English Pharmaceuticals Industries, Pakistan.
• O-lanz : Gray’s Pharmaceuticals, Pakistan.
• Nirvanol : Standpharm Pakistan (Pvt) Ltd.

Presently, Olanzia is available in Tablet form.

Olanzia Tablet : 5mg and 10mg strengths.

Olanzia tablets have certain contraindications, which means there are situations or conditions where the use of the medication is not recommended or should be avoided.

1. Hypersensitivity or Allergy: Individuals who have a known hypersensitivity or allergy to Olanzapine or any of the components in Olanzia tablet should avoid its use.
2. Severe Central Nervous System (CNS) Depression: Olanzia tablet may cause sedation and impair cognitive and motor skills. It should be used with caution, or avoided altogether, in individuals with severe CNS depression.
3. Coma: Olanzia tablet should not be used in individuals who are in a state of coma, as it may further depress the central nervous system.
4. Severe Cardiovascular Conditions: Olanzia tablet may lead to orthostatic hypotension (a sudden drop in blood pressure when changing positions), especially during the initial period of treatment. It should be used cautiously in individuals with severe cardiovascular conditions.
5. Uncontrolled Epilepsy: Olanzia tablet may lower the seizure threshold, and it should be used with caution in individuals with a history of seizures. In cases of uncontrolled epilepsy, alternative treatments may be considered.
6. Breastfeeding: Olanzia tablet passes into breast milk and may affect the nursing infant. It should be used with caution in breastfeeding mothers, and the potential benefits should be weighed against potential risks.
7. Parkinson’s Disease: Olanzia tablet may worsen symptoms of Parkinson’s disease. It should be used cautiously in individuals with Parkinson’s disease or Parkinsonian symptoms.
8. Dementia-Related Psychosis: Olanzia tablet is not approved for the treatment of dementia-related psychosis due to an increased risk of mortality in elderly patients with this condition.
9. History of Neuroleptic Malignant Syndrome (NMS): Individuals with a history of NMS, a potentially life-threatening condition associated with antipsychotic use, should avoid Olanzia tablets.
10. Concurrent Use with Clozapine: Olanzia tablet should generally not be used concurrently with clozapine due to an increased risk of severe adverse effects.

Olanzia Tablet Dose for Schizophrenia:

• Adults: One tablet of 10mg, once daily.
• However, the dosage may range from 5mg to 20mg per day, depending on individual response and the severity of symptoms.

Olanzia Tablet Dose for Bipolar Disorder (Manic or Mixed Episodes):

• Adults: (Starting Dose) One tablet of 10mg, once daily.
• Depending on the response, the dose may be adjusted between 5 mg and 20 mg per day.

Olanzia Tablet Dose for Agitation Associated with Schizophrenia and Bipolar Disorder:

• Adults: One tablet of 10mg. If necessary, a second dose may be given after 2 hours.

Olanzia Tablet for Other Off-label Uses:

• For off-label uses such as adjunctive treatment for depression, anxiety, or other conditions, the dosage will be determined by the healthcare provider based on the specific diagnosis and individual response.

Olanzia is an atypical antipsychotic medication. It is thought to work primarily by blocking dopamine and serotonin receptors in the brain.

• Dopamine is a neurotransmitter that is involved in a variety of functions, including movement, motivation, and reward.
• Serotonin is a neurotransmitter that is involved in mood, sleep, and appetite.