Klint Tablet Uses

Klint tablet is an antibiotic medication that is used to treat various bacterial and parasitic infections. The following are some common uses and indications of Klint Tablet:

1. Bacterial Infections: The use of Klint tablet is effective against a range of bacterial infections, including those caused by anaerobic bacteria. This includes infections in the abdomen, pelvis, skin, and respiratory tract.
2. Protozoal Infections: Klint tablets are also used to treat infections caused by certain types of single-celled organisms called protozoa. This includes infections like giardiasis (intestinal infection), trichomoniasis (a sexually transmitted infection), and amoebiasis (intestinal infection caused by Entamoeba histolytica).
3. Dental Infections: Klint tablet is sometimes prescribed for dental infections, particularly if the infection is severe or associated with an abscess.
4. Gastrointestinal Infections: It can be used to treat certain types of infections in the gastrointestinal tract, particularly those caused by anaerobic bacteria.
5. Bacterial Vaginosis: Klint tablet is often prescribed for the treatment of bacterial vaginosis, which is an overgrowth of certain types of bacteria in the vagina.
6. H. pylori Infections: It is part of the combination therapy used to treat Helicobacter pylori infections, which can cause stomach ulcers and other gastrointestinal problems.
7. Preventive Use: Klint tablet is sometimes given before certain surgical procedures to prevent infections.

Off-label Uses of Klint Tablet

1. Diverticulitis: In some cases, Klint tablet may be used as part of the treatment regimen for diverticulitis, particularly if the infection is severe.
2. Intra-abdominal Infections: Klint tablet may be used in combination with other antibiotics for the treatment of intra-abdominal infections.
3. Amoebiasis: In some cases, Klint tablet may be used to treat amoebic liver abscesses caused by Entamoeba histolytica.
4. Crohn’s Disease and Ulcerative Colitis: Klint tablet may be used as an adjunct therapy in the treatment of inflammatory bowel diseases like Crohn’s disease and ulcerative colitis.

Klint is one of the leading brands of Metronidazole, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

The following are some alternative brands of Klint and their manufacturers.

• Flagyl : Sanofi Aventis (Pakistan) Ltd.
• Gramex : Platinum Pharmaceuticals (Pvt) Ltd, Pakistan.
• Metrozine : Searle Pakistan (Pvt) Ltd.
• Riam : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Abozole : Abbott Laboratories (Pakistan) Ltd.
• Metni V : Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.
• Metrida : Zafa Pharmaceutical Laboratories (Pvt) Ltd, Pakistan.
• Neometin : Genom Pharmaceuticals (Pvt) Ltd, Pakistan.
• Amezole : Ferozsons Laboratories Ltd. Pakistan.
• Danizol : Don Valley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Flezole : Pearl Pharmaceuticals, Pakistan.

Presently, Klint is available in Tablet, Syrup, and Infusion forms.

• Klint Tablet : 400mg strength.
• Klint Syrup : 200mg/5ml strength.
• Klint Infusion : 500mg/100ml strength.

Klint is an antibiotic medication with certain contraindications, which are medical conditions or situations in which its use is not recommended or should be avoided due to potential risks.

• Hypersensitivity: Do not use Klint tablet if you are allergic or hypersensitive to Metronidazole or any of its components. Allergic reactions can be severe and may include rash, itching, swelling, severe dizziness, or difficulty breathing.
• Pregnancy: Klint tablets should be used with caution during pregnancy. It is typically avoided during the first trimester, and its use should only be considered if the potential benefits outweigh the risks. Your healthcare provider will assess the situation and recommend the most appropriate treatment.
• Breastfeeding: Klint can be excreted in breast milk, so its use should be discussed with a healthcare provider. In some cases, breastfeeding may need to be temporarily discontinued during treatment.
• Alcohol Consumption: Avoid consuming alcohol while taking the Klint tablet and for at least 48 hours after the last dose. The combination of alcohol and Klint tablet can cause a severe reaction known as a disulfiram-like reaction, characterized by symptoms like flushing, nausea, vomiting, and rapid heart rate.
• Blood Disorders: Klint tablet can affect blood cell counts and may not be suitable for individuals with blood disorders or a history of blood-related problems. Your healthcare provider will assess the risk and benefit for your specific situation.
• Liver Disease: People with severe liver disease may not be able to metabolize Klint tablets properly, which can lead to increased levels of the drug in the body. In such cases, an alternative treatment may be considered.
• Neurological Disorders: Klint tablet can cause neurological side effects, including seizures and peripheral neuropathy. It should be used with caution in individuals with a history of neurological disorders or seizures.
• Interaction with Disulfiram: If you are taking disulfiram (a medication used to treat alcohol dependence), Klint tablet should be avoided due to the potential for adverse reactions.
• Interaction with Warfarin: Klint tablet can increase the effect of warfarin, an anticoagulant medication. If you are taking warfarin, your healthcare provider may need to adjust the dosage and monitor your blood clotting times closely.
• Trichomoniasis in Pregnancy: Although Klint tablet is commonly used to treat trichomoniasis in non-pregnant individuals, it is generally avoided in the first trimester of pregnancy. Pregnant women with trichomoniasis may require alternative treatments.

Klint Tablet Dose for Bacterial Infections:

• For most bacterial infections: 1 – 2 tablets, every 8 hours (three times a day) for 7 to 10 days.
• This dosage may vary depending on the severity of the infection.

Klint Tablet Dose for Bacterial Vaginosis:

• One tablet, twice daily for 7 days.

Klint Tablet Dose for Trichomoniasis:

• 2-gram dose (five 400 mg tablets taken at once) or a Half to One Tablet, twice daily for 7 days.

Klint Tablet Dose for Amoebic Infections:

• 1 – 2 tablets, every 8 hours (three times a day) for 5 to 10 days.

Klint tablet disrupts the synthesis of nucleic acids (DNA and RNA) in microorganisms. This inhibition of nucleic acid production interferes with the microorganism’s ability to replicate and carry out essential cellular processes.