Kamic tablet is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for the relief of pain and inflammation associated with various conditions, including:

  1. Pain Relief: Kamic Forte is commonly used to alleviate mild to moderate pain, including dysmenorrhea, dental pain, postoperative pain, headache, muscle pain, and joint pain. It helps reduce pain by inhibiting the production of prostaglandins, which are substances that play a role in pain and inflammation.
  2. Menstrual Disorders: Kamic Forte is particularly effective in relieving menstrual pain (dysmenorrhea). It can help reduce uterine contractions and decrease the production of prostaglandins, which are associated with menstrual cramps. Kamic Forte is typically taken for a short duration during the menstrual period to alleviate pain.
  3. Inflammatory Conditions: Kamic Forte can be used to manage inflammatory conditions such as arthritis (including rheumatoid arthritis and osteoarthritis), gouty arthritis, and other musculoskeletal disorders associated with pain and inflammation. It helps reduce swelling, joint stiffness, and pain in these conditions.
  4. Postoperative Pain: Kamic Forte may be used to manage pain following surgical procedures. It can help alleviate pain associated with inflammation at the surgical site and promote postoperative recovery.

Off-label Uses of Kamic Tablet

  1. Migraine Headache: Kamic Forte has been used off-label for the treatment of acute migraine attacks. It may help reduce the intensity and duration of migraines by inhibiting the production of prostaglandins, which are involved in the inflammatory process associated with migraines. However, specific migraine medications are typically preferred for this indication, and the evidence for Kamic Forte’s efficacy in migraine treatment is limited.
  2. Postpartum Pain: Kamic Forte has been used off-label to relieve pain associated with the postpartum period (after childbirth). It may help reduce pain and inflammation in the uterus and pelvic region during the recovery period. However, the use of Kamic Forte in the postpartum period should be done under the guidance of a healthcare professional.
  3. Dysfunctional Uterine Bleeding: Kamic Forte has been used off-label to manage dysfunctional uterine bleeding, which refers to abnormal or irregular bleeding from the uterus. It may help reduce excessive bleeding and relieve associated pain. However, it’s important to investigate and address the underlying cause of dysfunctional uterine bleeding before considering Kamic Forte or any other treatment option.
Kamic Forte Uses and Indications

What is Kamic Forte?

Kamic is one of the leading brands of Mefenamic Acid, manufactured and marketed by Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.

Kamic Forte Tablet is a double dose of Mefnamic Acid (Kamic).

Kamic Alternatives : Other Similar Brands

The following are some alternative brands of Kamic Forte and their manufacturers.

  • Ponstan : Pfizer Laboratories Inc.
  • Mefnac : Efroz Chemical Industries (Pvt) Ltd, Pakistan.
  • Mefacid : Zafa Pharmaceutical Laboratories (Pvt) Ltd, Pakistan.
  • Dolor : Adamjee Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Zopan : Pharmatec Pakistan (Pvt) Ltd.
  • Boschtan : Bosch Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Febrin : Remington Pharmaceutical Industries (Pvt) Ltd, Pakistan.
  • Fenamic : Unexo Labs (Pvt) Ltd, Pakistan.
  • Mefadil : P.D.H Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Mefgesic : Wilsons Pharmaceuticals, Pakistan.

Kamic : Available Formulations and Strengths

Presently, Komic Forte is available in Tablet form

Kamic Forte Tablet : 500mg strength.

Kamic Tablet : 250mg strength.

Who Should Not Use Kamic?

Kamic Forte has certain contraindications, which means there are circumstances or medical conditions in which its use is not recommended.

  • Hypersensitivity: Kamic Forte is contraindicated in individuals who have a known hypersensitivity or allergy to Kamic Forte or other NSAIDs (nonsteroidal anti-inflammatory drugs). If an allergic reaction occurs after taking Kamic Forte, such as rash, itching, swelling, or difficulty breathing, medical attention should be sought immediately.
  • History of asthma, rhinitis, or urticaria: Kamic Forte is contraindicated in individuals who have a history of asthma, rhinitis (nasal inflammation), or urticaria (hives) induced by NSAIDs. NSAIDs, including Kamic Forte, may trigger respiratory or allergic reactions in susceptible individuals.
  • Active peptic ulcer or gastrointestinal bleeding: Kamic Forte is contraindicated in individuals with active peptic ulcers (open sores in the stomach or intestine) or a history of gastrointestinal bleeding. NSAIDs can increase the risk of ulcers and gastrointestinal bleeding, and using Kamic Forte in such cases can exacerbate these conditions.
  • Severe renal impairment: Kamic Forte should be used with caution or avoided in individuals with severe renal impairment (kidney disease). It is excreted by the kidneys, and impaired kidney function may lead to the accumulation of the drug in the body. Dosing adjustments or alternative treatments may be necessary in such cases.
  • Severe hepatic impairment: Kamic Forte should be used with caution or avoided in individuals with severe hepatic impairment (liver disease). It may further compromise liver function and increase the risk of adverse effects. Dosing adjustments or alternative treatments may be necessary in such cases.
  • Pregnancy and breast-feeding: Kamic Forte is generally not recommended during pregnancy, especially in the third trimester, as it may have adverse effects on the fetus. It is also not recommended during breastfeeding as it may pass into breast milk and affect the nursing infant.

What is the Recommended Daily Dosage of Kamic?

Kamic Forte Dose for Pain Relief:

  • Adults: One Tablet of Kamic Forte (500mg),
  • Followed by: One Tablet of Kamic (250mg) every 6 hours as needed.
  • The maximum daily dose should not exceed 3 grams (3,000 mg).

Kamic Forte Dose for Dysmenorrhea (menstrual pain):

  • Adults: One Tablet of Kamic Forte (500mg),
  • Followed by: One Tablet of Kamic (250mg) every 6 hours as needed.
  • The maximum daily dose should not exceed 1.5 grams (1,500 mg).
  • Treatment is typically initiated at the onset of menstrual pain and continued for a few days.

How Kamic Works?

Kamic works by inhibiting the activity of cyclooxygenase enzymes, particularly COX-1 and COX-2. These enzymes are involved in the production of prostaglandins, which are hormone-like substances that play a role in inflammation, pain, and fever.