Inventive Syrup Uses

Inventive Syrup is a medication that is primarily used to alleviate and suppress dry, non-productive coughs. It helps to reduce the urge to cough. It is a non-narcotic cough suppressant, which means that it does not have the same addictive potential as other cough suppressants. The following are some common uses and indications of Inventive Syrup:

1. Common Cold: The use of Inventive syrup can help reduce coughing caused by viral infections that affect the upper respiratory tract, such as the common cold.
2. Influenza (Flu): Inventive syrup may be used to provide relief from coughing associated with the flu, which can cause irritating and persistent coughs.
3. Bronchitis: Using Inventive syrup can help manage coughing in cases of acute or chronic bronchitis, which involves inflammation of the airways.
4. Upper Respiratory Tract Infections: Inventive syrup can be used to relieve coughing due to various infections affecting the nose, throat, and airways.

Off-label Uses of Inventive Syrup

1. Opioid-Induced Cough: Inventive syrup has been trialed for its potential to alleviate coughing caused by certain opioids, particularly those that act on specific receptors in the brain.
2. Chronic Cough: In some cases, Inventive syrup might be considered as a treatment option for chronic cough that has not responded to other therapies.
3. Post-Infectious Cough: Following certain respiratory infections, individuals may experience prolonged coughing. This syrup could be used to manage this type of cough.
4. Cough Associated with Asthma: Inventive syrup is used for managing coughing in asthma patients when standard asthma medications alone are not sufficient.

Inventive Syrup is one of the leading brands of Dimemorfan Phosphate, manufactured and marketed by Amson Vaccines & Pharma (Pvt) Ltd, Pakistan.

The following Syrup Brands are not similar in composition to Inventive Syrup but they can be used for Dry or Non-productive coughs.

Acefyl : Nabi Qasim Industries (Pvt) Ltd, Pakistan.

Cosome-E : Martindow Marker (Pvt) Ltd, Pakistan.

Rondec C : Abbott Laboratories (Pakistan) Ltd.

Hydryllin DM : Searle Pakistan Ltd.

Muconyl : Barrett Hodgson Pakistan (Pvt) Ltd.

Siroline : Le Mendoza Pharmaceuticals (Pvt) Ltd, Pakistan.

Actified DM : GlaxoSmithKline (GSK).

Corex D : Pfizer Laboratories Inc.

Presently, Inventive is available in syrup form with 60ml and 120ml strength.

Inventive Syrup Each 5ml Contains:

• Dimemorfan Phosphate: 12.5mg

Despite the potential benefits of Inventive Syrup uses discussed above, there are several contraindications that must be taken into consideration before beginning a course of treatment.

Inventive syrup is contraindicated in people who are:

• Allergic to dimemorfan or any of the other ingredients in the syrup.
• Taking MAOIs.
• Pregnant or breastfeeding women, unless absolutely necessary.
• Under 6 years of age.

Inventive syrup should also be used with caution in people with the following conditions:

• Liver disease.
• Kidney disease.
• Asthma.
• Narrow-angle glaucoma.
• Heart disease.
• High blood pressure.
• Seizures.
• Overactive thyroid.

If you have any of these conditions, you should talk to your doctor before taking Inventive Syrup.

Here are some other things to keep in mind about Inventive syrup:

It should not be taken with other medications that can cause drowsiness, such as alcohol, sedatives, or tranquilizers.
It should not be taken for more than 7 days without consulting a doctor.
If you experience any side effects, such as drowsiness, dizziness, dry mouth, or constipation, stop taking the syrup and talk to your doctor.

Inventive Syrup Dose for Adults:

10-20 mg (Approximately 2 – 4 Teaspoons) every 4-6 hours, as needed.

The maximum daily dose is 120 mg.

Inventive Syrup Dose for Children: (the dosage is based on age)

• Children 6-12 years: 5-10 mg (1 – 2 Teaspoons) every 4-6 hours, as needed.
• Children 2-6 years: 2.5-5 mg (1/2 – 1 Teaspoon) every 4-6 hours, as needed.
• Children under 2 years: Not recommended.

The exact mechanism by which Inventive syrup suppresses coughing is not fully understood, but it is believed to involve interactions with certain receptors in the brain. Inventive is thought to bind to sigma-1 receptors in the CNS, which leads to its antitussive effects.

By affecting these receptors, Inventive reduces the brain’s sensitivity to the cough reflex, effectively decreasing the urge to cough. This mechanism helps provide relief from dry, non-productive coughs associated with various respiratory conditions.