Inderal Tablet Uses

Inderal tablet is primarily used for cardiovascular issues like hypertension and angina. It belongs to the class of drugs called beta-blockers. Following are some common uses of Inderal Tablet:

1. Hypertension (High Blood Pressure): Inderal tablet is frequently used for the treatment of hypertension. It blocks the effects of certain chemicals that tighten the blood vessels, leading to a decrease in blood pressure.
2. Angina: Inderal tablet is used to manage angina, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart. By reducing the workload on the heart and improving blood flow, Inderal helps relieve angina symptoms.
3. Arrhythmias: Inderal tablet is used to treat certain types of abnormal heart rhythms or arrhythmias. It helps regulate heart rate and rhythm, reducing the frequency and severity of irregular heartbeats.
4. Tremors: Inderal tablet is sometimes used for the management of essential tremors, a neurological disorder characterized by involuntary shaking of the hands, head, or other body parts. It can help reduce the intensity and frequency of tremors, improving functional abilities.
5. Migraine Prevention: Inderal tablet is also used for the prevention of migraines in some cases. It reduces the frequency and severity of migraine attacks, although the exact mechanism is not fully understood.
6. Performance Anxiety and Stage Fright: Inderal tablets may be used to manage symptoms of performance anxiety or stage fright. It helps reduce the physical symptoms associated with anxiety, such as rapid heart rate, sweating, and tremors.
7. Hyperthyroidism: Inderal tablets can be used temporarily to control symptoms of hyperthyroidism, a condition in which the thyroid gland produces excessive amounts of thyroid hormones. It helps alleviate symptoms like rapid heart rate, tremors, and anxiety until definitive treatment for hyperthyroidism is initiated.

Off-label Uses of Inderal Tablet

1. Post-Traumatic Stress Disorder (PTSD): Inderal tablet is used off-label to manage the symptoms of PTSD, such as intrusive memories and hyperarousal. It helps reduce the intensity of emotional memories by interfering with memory consolidation.
2. Thyroid Storm: Inderal tablets can be used as an adjunctive treatment for thyroid storm, a life-threatening condition characterized by severe overactivity of the thyroid gland. It helps control the symptoms of increased heart rate, tremors, and anxiety associated with thyroid storm until definitive treatment can be initiated.
3. Infantile Hemangiomas: Inderal tablet has been used off-label in the treatment of infantile hemangiomas, which are benign vascular tumors that can occur in infants. Inderal can help shrink and fade these hemangiomas, although its use in this context requires close monitoring and should be done under the supervision of a pediatric specialist.
4. Portal Hypertension: Inderal tablets can be to manage portal hypertension, a condition characterized by high blood pressure in the portal vein system of the liver. By reducing portal vein pressure, Inderal helps prevent complications such as variceal bleeding in individuals with liver cirrhosis.

Inderal is one of the leading brands of Propranolol, manufactured and marketed by ICI (Pakistan) Ltd.

The following are some alternative brands of Inderal and their manufacturers.

• Opriol : Abbott Laboratories (Pakistan) Ltd.
• Betanol : Rakaposhi Pharmaceuticals (Pvt) Ltd, Pakistan.
• Opinol : Glitz Pharma.
• Propraolol : Siza International (Pvt) Ltd, Pakistan.
• Betablock : Pakistan Pharmaceutical Products (Pvt) Ltd.
• Cardioset : Lisko Pakistan (Pvt) Ltd.
• Caraprop : Caraway Pharmaceuticals, Pakista.
• Cardinol : Specer Pharma.
• Hyporide : Usawa Pharmaceuticals.
• Blokonol : Lisko Pakistan (Pvt) Ltd.

Presently, Inderal is available in Tablets Form.

Inderal Tablets : 10mg and 40mg strengths.

Inderal LA Tablets : 80mg strength.

Inderal has specific contraindications, which are situations or conditions in which the use of the medication is not recommended due to potential risks or adverse effects. It’s important to be aware of these contraindications before using Inderal.

Hypersensitivity: Inderal is contraindicated in individuals who have a known hypersensitivity or allergic reaction to Inderal or any of its components. Signs of hypersensitivity may include rash, itching, swelling, or difficulty breathing. If you have a known hypersensitivity, an alternative medication should be considered.

Bradycardia and Heart Block: Inderal is contraindicated in individuals with bradycardia (a slow heart rate) or heart block (a disruption in the electrical signals that regulate the heart rhythm) unless they have a functioning artificial pacemaker. Inderal can further slow down the heart rate or worsen heart block, potentially leading to more serious complications.

Uncontrolled Heart Failure: Inderal is contraindicated in individuals with uncontrolled heart failure. It can worsen heart failure symptoms and may not be safe in this population. Inderal should be used with caution in patients with stable heart failure who are already receiving appropriate treatment.

Asthma and Chronic Obstructive Pulmonary Disease (COPD): Inderal is generally contraindicated in individuals with asthma or COPD due to its potential to cause bronchospasm and worsen respiratory symptoms. However, in some cases, Inderal may be cautiously used under close medical supervision.

Peripheral Vascular Disease: Inderal is contraindicated in individuals with severe peripheral arterial disease, a condition characterized by poor blood circulation in the arms and legs. Inderal can further reduce blood flow to the extremities, exacerbating symptoms.

Raynaud’s Disease: Inderal is generally contraindicated in individuals with Raynaud’s disease, a condition that causes the narrowing of blood vessels in response to cold or stress. Inderal can worsen the symptoms by further reducing blood flow to the affected areas.

Inderal Tablets (10mg, 40mg, and 80mg) Dosage

Inderal Dose for Hypertension (High Blood Pressure): One tablet of 40mg twice daily. The dosage may be adjusted based on individual response, and higher doses, up to 320 mg per day, may be prescribed.

Inderal Dose for Angina: One tablet of 40mg twice daily. The dose may be adjusted based on the individual’s response and can range from 80 mg to 320 mg per day.

Inderal Dose for Arrhythmias: 1-3 tablets of 10mg three to four times daily. The dosage may be adjusted based on the specific arrhythmia being treated and individual response.

Inderal Dose for Essential Tremor: One tablet of 40mg twice daily. The dose may be gradually increased to a maximum of 120-240 mg per day, divided into multiple doses.

Inderal Dose for Migraine Prevention: One tablet of Inderal-LA (80mg) per day. The dose may be increased up to 240 mg per day, based on individual response.

Inderal is a beta-blocker medication and works by blocking the effects of adrenaline and other stress hormones on beta-adrenergic receptors in the body. By doing so, it exerts various effects on the cardiovascular system and other body systems.

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