Gynosporin cream is primarily used as an antifungal medication that is applied topically to the skin to treat fungal infections. Gynosporin cream works by disrupting the cell membranes of fungal organisms, preventing their growth and multiplication.

About Gynosporin Cream

  • Generic Name: Clotrimazole
  • Properties: Antimycotic (Anti-fungal)
  • Manufactured and Marketed By: Nabiqasim Industries (Pvt) Ltd
  • Presentation: 5gm & 35gm Tube (Vaginal Cream) – 100mg & 500mg (Vaginal Tablet)
Gynosporin Cream Uses and Indications

Common Uses and Indications of Gynosporin Cream

  1. Vaginal Infections: Gynosporin cream is used to treat vaginal infections that are caused by a combination of bacterial and fungal factors. It is particularly effective when the infection involves both bacterial overgrowth and yeast overgrowth.
    • Bacterial Vaginosis: Bacterial vaginosis (BV) is a common vaginal infection caused by an imbalance of bacteria in the vagina. Gynosporin cream can help address the bacterial component of BV.
    • Vulvovaginal Candidiasis (Vaginal Yeast Infection): This cream also treats vaginal yeast infections, which are caused by the overgrowth of Candida yeast.
  2. Candidal Balanitis: Gynosporin cream can be used to treat candidal balanitis, a fungal infection of the head of the penis.
  3. Pityriasis Versicolor: Gynosporin cream can be used to treat pityriasis versicolor, a skin condition caused by the overgrowth of a type of yeast.
  4. Fungal Nail Infections (Onychomycosis): Gynosporin cream can be applied around the edges of infected nails to help control fungal growth and prevent spreading.
  5. Yeast Infections: Gynosporin cream can be used to treat yeast infections caused by Candida species, especially candidal skin infections, including diaper rash in infants and intertrigo in adults.
  6. Skin Folds (Intertrigo): Gynosporin cream may be used to treat fungal infections that develop in skin folds, such as under the breasts or in the groin area.

Off-label Uses of Gynosporin Cream

  1. Thrush: Thrush is a yeast infection that can affect the mouth, throat, or vagina. Gynosporin cream may be effective for treating thrush in the mouth or throat, but it is not as effective for treating vaginal thrush.
  2. Cradle cap: Cradle cap is a common skin condition in babies that causes scaly, crusty patches on the scalp. Gynosporin cream may be effective for treating cradle caps, but it is not the first-line treatment.
  3. Intertrigo: Intertrigo is a rash that can occur in skin folds, such as the armpits or groin. Gynosporin cream may be effective for treating intertrigo, but it is not the first-line treatment.
  4. Preventive Use: In certain cases, healthcare providers might consider using Gynosporin cream as a preventive measure to reduce the risk of infection in areas prone to both bacterial and fungal overgrowth.

Benefits of Gynosporin Cream

Soothing Relief from Irritations: One of the primary benefits of Gynosporin cream is its ability to provide rapid relief from skin irritations, including itching, redness, and burning sensations. It creates a soothing barrier that helps alleviate discomfort.

Combating Bacterial and Fungal Infections: Gynosporin cream’s formulation is effective against a wide range of bacteria and fungi, making it a versatile option for addressing different types of infections. It actively fights against the underlying causes of skin issues.

Aiding in Skin Repair: Beyond its antibacterial and antifungal properties, Gynosporin cream contains components that support skin repair. This can accelerate the healing process, helping the skin recover faster from minor injuries or infections.

Formulation and Ingredients

  • Clotrimazole: 2%w/w

Gynosporin cream typically contains Clotrimazole, which works in tandem to eliminate harmful microorganisms. Additionally, it often includes soothing agents that provide comfort to the affected area.

The Synergistic Action of Ingredients: The combination of antibiotic and antifungal ingredients in Gynosporin cream creates a synergistic effect, targeting a broad spectrum of pathogens. This dual action enhances its effectiveness in treating various skin issues.

Application of Gynosporin Cream

Proper Steps for Application:

To apply Gynosporin cream, first, clean and dry the affected area. Then, apply a thin layer of the cream and gently massage it into the skin. Wash your hands after application to prevent the spread of bacteria or fungi.

Contraindications and Precautions of Gynosporin Cream

Contraindications:

  1. Hypersensitivity or Allergy: Individuals who have a known hypersensitivity or allergy to neomycin sulfate, clotrimazole, or any of the components of the cream should not use it.
  2. Perforated Eardrum: Neomycin sulfate, one of the active ingredients, should not be used in the ear if the eardrum is perforated (has a hole), as it can potentially lead to hearing loss.
  3. Viral Infections: Gynosporin cream is not intended for the treatment of viral infections. It is specifically formulated for bacterial and fungal infections.
  4. Eye Application: Gynosporin cream is not formulated for use in the eyes. If you require treatment for eye infections, other formulations should be used under medical supervision.
  5. Systemic Use: Gynosporin cream is intended for topical use only and should not be ingested or used internally.
  6. Pregnancy and Breastfeeding: The use of Gynosporin cream during pregnancy and breastfeeding may require caution and should be discussed with a healthcare professional. The topical use of clotrimazole is generally considered safer than systemic use.

Precautions:

  1. Superinfections: Prolonged use of antibiotics, including neomycin sulfate, can sometimes lead to the development of secondary infections or the overgrowth of non-susceptible organisms. If this occurs, treatment should be re-evaluated.\
  2. Pediatric Use: Gynosporin cream is generally not recommended for use in infants without medical supervision due to concerns about potential sensitization and limited data in this age group.
  3. Vaginal Irritation: Some individuals may experience mild irritation or burning when using vaginal creams. If irritation is severe or persistent, discontinuation of use and consultation with a healthcare provider is recommended.

Precautions for Safe Application:

It’s essential to follow the recommended application guidelines. Avoid using excessive amounts of the cream, and refrain from applying it to open wounds, mucous membranes, or the eyes.

Frequently Asked Questions

  1. Q: Is Gynosporin cream available without a prescription?
    Yes, Gynosporin cream is typically available over the counter at pharmacies.
  2. Q: Can I use Gynosporin cream on open wounds?
    No, Gynosporin cream is not recommended for open wounds. It’s intended for external use on intact skin.
  3. Q: How often should I apply Gynosporin cream?
    You can apply Gynosporin cream 2-3 times a day, or as directed by a healthcare professional.
  4. Q: Can Gynosporin cream be used for children’s skin issues?
    Consult a pediatrician before using Gynosporin cream on children, especially for infants or young children.
  5. Q: Is Gynosporin cream suitable for sensitive skin?
    Gynosporin cream is generally safe for most skin types, but if you have sensitive skin, consider doing a patch test before widespread application.

Gynosporin Cream’s Alternatives : Other Similar Brands

The following are Some alternative brands of Gynosporin Cream and their manufacturers.

  • Canesten : Bayer Schering Pharma.
  • Dermosporin : Nabiqasim Industries (Pvt) Ltd, Pakistan.
  • Aquazole : Martin Dow Marker Pakistan (Pvt) Ltd.
  • Hydrozole : Stiefel Laboratories Pakistan (Pvt) Ltd.
  • Creamazole : Valor Pharmaceutical, Pakistan.
  • Biotrim : Bio Labs (Pvt) Ltd, Pakistan.
  • Cara-Clot : Caraway Pharmaceuticals, Pakistan.
  • Clomazol : Pharmawise Labs. (Pvt) Ltd, Pakistan.
  • Clonil Skin : Mediceena Pharma (Pvt) Ltd, Pakistan.
  • Cloteen-V : Highnoon Laboratories Ltd, Pakistan.
  • Clozim-6 : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
  • Clozox : Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.