Cosome-E Syrup Uses

Cosome-E Syrup is a combination medicine that is primarily used to treat cough, allergies, and other respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). Cosome E syrup also has a cooling and numbing effect that can help soothe a cough and ease throat irritation. This can be helpful for coughs caused by colds, the flu, or even dry air. The following are some common and off-label uses of Cosome-E syrup:

Common Uses and Indications of Cosome-E Syrup

• Bronchitis
• Asthma-associated Cough
• Pneumonia
• Emphysema
• Chronic Obstructive Pulmonary Disease (COPD)
• Allergic Rhinitis
• Hay Fever
• Productive Cough
• Cough due to Smoking
• Cough with Allergies

Off-label Uses of Cosome-E Syrup

Sometimes Cosome-E Syrup is also used off-label for the following purposes:

• Motion sickness. The antihistamine diphenhydramine in Cosome-E Syrup can help to prevent motion sickness.
• Insomnia. The antihistamine diphenhydramine in Cosome-E Syrup can help to promote sleep.
• Parkinson’s disease. The bronchodilator aminophylline in Cosome-E Syrup can help to improve symptoms of Parkinson’s disease.

Cosome-E Syrup is a combination of Ammonium Hydrochloride, Diphenhydramine HCl, Aminophylline, and Menthol, manufactured and marketed by Martindow Marker (Pvt) Ltd, Pakistan.

Below are some available similar brands that can be used as an alternative to Cosome-E Syrup:

• Hydryllin : Searle Pakistan (Pvt) Ltd, Pakistan
• Combinol E : Atco Laboratories Ltd, Pakistan.
• Lotus : Indus Pharma (Pvt) Ltd, Pakistan.
• Coldrex-E : Standpharm Pakistan (Pvt) Ltd.
• Adalin : Macter International (Pvt) Ltd, Pakistan.
• Rexyl : Nabiqasim Industries (Pvt) Ltd, Pakistan.
• Cofllin : Bio Labs (Pvt) Ltd, Pakistan.
• Broxol : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Standryllin : Standard Drud Co, Pakistan
• Bronil : Star Laboratories (Pvt) Ltd, Pakistan.

Presently, Cosome is available in Syrup form with the following Generic and Brand names.

Cosome-E Syrup Bronchodilator/Cough Syrup

Each 5ml Contains:

• Ammonium Hydrochloride: 30mg
• Diphenhydramine HCl: 8mg
• Aminophylline: 32mg
• Menthol: 0.98mg

Cosome Syrup Decongestant/Non-Productive Cough Syrup

Each 5ml Contains:

• Dextromethorphan: 10mg
• Pseudoephedrine (Maleate): 2mg
• Chlorpheniramine (HCl): 30mg

Cosome-E Syrup is not safe for everyone to take. It is contraindicated for people with the following conditions:

• Asthma. Cosome-E Syrup can worsen asthma symptoms.
• Heart disease. Cosome-E Syrup can increase the heart rate and blood pressure.
• Liver disease. Cosome-E Syrup can be toxic to the liver.
• Glaucoma. Cosome-E Syrup can increase eye pressure.
• Pregnancy. Cosome-E Syrup can cause birth defects.
• Breastfeeding. Cosome-E Syrup can pass into breast milk and harm the baby.

The recommended daily dose of Cosome-E Syrup depends on the age and weight of the individual.

Cosome-E Syrup Dose for Adults and Children (12 years and older):

• 2 teaspoons (10 ml) every 4 to 6 hours, as needed.

Cosome-E Syrup Dose for Children (6 to 11 years):

• 1 teaspoon (5 ml) every 4 to 6 hours, as needed.

Cosome-E Syrup Dose for Children (2 to 5 years):

• 1/2 teaspoon (2.5 ml) every 4 to 6 hours, as needed.

Cosome-E Syrup is a combination medicine, and each ingredient has a different mode of action:

1. Ammonium Hydrochloride: Ammonium Hydrochloride acts as an expectorant. It helps to thin and loosen mucus in the airways, making it easier to cough up and clear the respiratory passages. By promoting the clearance of mucus, it can alleviate symptoms such as chest congestion and cough.
2. Diphenhydramine HCl: Diphenhydramine HCl is an antihistamine with antitussive properties. It works by blocking the effects of histamine, reducing cough reflex sensitivity, and providing relief from coughing. Diphenhydramine HCl can also help alleviate symptoms such as sneezing, runny nose, and watery eyes.
3. Aminophylline: Aminophylline is a bronchodilator that helps to relax and widen the airways. It works by inhibiting the enzyme phosphodiesterase, which leads to the relaxation of smooth muscles in the bronchioles. This action helps to relieve bronchospasm and improve airflow in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
4. Menthol: Menthol provides a cooling and soothing effect on the throat and airways. It has a local anesthetic effect that can temporarily relieve throat irritation and suppress the urge to cough. Menthol also helps to provide a sensation of easier breathing by stimulating cold receptors in the airways.