Cobolmin Tablet Uses

Cobolmin tablet is a form of vitamin B12 that plays a crucial role in various bodily functions, particularly in the nervous system. Cobolmin tablets are used to address conditions related to vitamin B12 deficiency. The following are some common uses and indications of Cobolmin Tablet:

1. Treatment of Vitamin B12 Deficiency: Cobolmin tablets are commonly used to treat or prevent vitamin B12 deficiency. This deficiency can lead to symptoms like anemia, fatigue, weakness, and neurological problems.
2. Pernicious Anemia: Cobolmin is the primary treatment for pernicious anemia, a condition where the body can’t absorb enough vitamin B12 from the digestive tract.
3. Nerve Function and Health: Cobolmin is crucial for maintaining healthy nerve cells. It helps in the production of the protective covering of nerves (myelin sheath) and supports nerve function.
4. Neurological Disorders: Some neurological conditions, like peripheral neuropathy, certain forms of dementia, and certain types of neuropathic pain, may benefit from Cobolmin tabletation.
5. Improving Cognitive Function: Cobolmin may be used to support cognitive function, especially in elderly individuals who may be at risk for cognitive decline.
6. Treatment of Diabetic Neuropathy: Diabetic neuropathy is a condition where nerve damage occurs due to diabetes. Cobolmin has been used to help alleviate symptoms associated with this condition.
7. Chronic Fatigue Syndrome: Some individuals with chronic fatigue syndrome may benefit from using Cobolmin tablet, as it is involved in energy metabolism.
8. Supporting Mood and Mental Health: Some studies suggest that maintaining sufficient vitamin B12 levels, including Cobolmin, may contribute to improved mood and mental well-being.
9. Visual Health: Cobolmin may play a role in maintaining the health of the optic nerve and supporting overall visual function.
10. Digestive Health: Vitamin B12, including Cobolmin, plays a role in maintaining the health of the digestive system. It supports the normal function of the gastrointestinal tract.
11. Prevention of Birth Defects: Adequate vitamin B12 levels during pregnancy, including Cobolmin, are important for preventing certain birth defects in the baby’s neural tube.

Off-label Uses of Cobolmin Tablet

1. Alleviating Neuropathic Pain: Cobolmin tablet may be used to help manage certain types of neuropathic pain, which is pain caused by damage or dysfunction of the nervous system.
2. Supporting Wound Healing: Some studies have explored the potential benefits of Cobolmin tablets in wound healing, particularly in cases where nerve damage is involved.
3. Multiple Sclerosis (MS): While not a primary treatment for MS, Cobolmin tablet may be considered as part of a comprehensive treatment plan for some individuals with multiple sclerosis, especially those with symptoms related to nerve function.
4. Chronic Fatigue Syndrome (CFS): Cobolmin tablet supplements may be used to help address symptoms of chronic fatigue syndrome, as it is involved in energy metabolism.
5. Cognitive Function in the Elderly: Some trials have investigated the potential role of Cobolmin tablets in supporting cognitive function, especially in elderly individuals who may be at risk for cognitive decline.
6. Depression and Anxiety: There is limited evidence suggesting that Cobolmin tablet supplementation may have a positive impact on mood and mental well-being.
7. Amyotrophic Lateral Sclerosis (ALS): Cobolmin tablet may be considered as part of a comprehensive treatment plan for ALS, a neurodegenerative disorder affecting nerve cells in the brain and spinal cord.
8. Chemotherapy-Induced Peripheral Neuropathy (CIPN): Cobolmin tablet has been explored as a potential treatment or supportive measure for individuals experiencing nerve damage as a side effect of chemotherapy.
9. Stroke Recovery: Some studies have investigated the potential role of Cobolmin tablet in supporting neurological recovery after a stroke.

Cobolmin is one of the leading brands of Mecobalamin, manufactured and marketed by Macter International (Pvt) Ltd.

The following are some alternative brands of Cobolmin and their manufacturers.

• Methycobal : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Mabil : Sami Pharmaceuticals (Pvt) Ltd Pakistan.
• Neuromet : Merck Serono Pharmaceutical.
• Mecobal : NabiQasim Pharmaceuticals, Pakistan.
• Nervon : Getz Pharmaceuticals, Pakistan.
• Mecogen : Genetics Pharmaceuticals, Pakistan.
• Qbal : Bosch Pharmaceuticals, Pakistan
• Bezel : Saffron Pharmaceuticals, Pakistan.
• Incobal : Indus Pharmaceuticals, Pakistan.
• Elgin : Novartis, Pakistan.
• Mylaxzon : Barrett Hodgson Pharmaceuticals, Pakistan.

Presently, Cobolmin is available in Tablet and Injection forms.

Cobolmin Tablet : 500mcg strength.

Cobolmin Injection : 500mcg/ml strength.

Cobolmin tablets like any medication, have specific contraindications, which are situations where the use of the medication is not recommended or should be avoided.

• Hypersensitivity: Individuals who have a known hypersensitivity or allergy to Cobolmin or any of the other ingredients in the tablet should not take it.
• Leber’s Disease: Cobolmin should not be used in individuals with Leber’s hereditary optic neuropathy, a rare genetic disorder that can lead to vision loss.
• Polycythemia Vera: This is a rare blood disorder characterized by an excess of red blood cells. Cobolmin may exacerbate this condition.
• Elevated Serum Potassium Levels: Cobolmin can potentially increase serum potassium levels, which can be problematic for individuals with certain kidney conditions or those taking medications that affect potassium levels.
• Active Allergies or Skin Conditions: Individuals with active allergies or skin conditions should use caution, as Cobolmin may exacerbate these conditions.
• Leukemia: Cobolmin should be used with caution in individuals with certain forms of leukemia, as it may stimulate the production of red blood cells.
• Cancer with Elevated Serum Potassium: In individuals with cancer associated with elevated serum potassium levels, Cobolmin should be used with caution.
• Epilepsy and Seizure Disorders: Cobolmin may lower the seizure threshold in individuals with epilepsy or seizure disorders.
• Pediatric Use: The safety and effectiveness of Cobolmin in children have not been established in some cases. It should be used with caution and under the guidance of a healthcare provider.
• Pregnancy and Breastfeeding: The use of Cobolmin during pregnancy and breastfeeding should be carefully considered. It’s important to weigh the potential benefits against potential risks, and the decision should be made in consultation with a healthcare provider.

Cobolmin Dose for Vitamin B12 Deficiency:

• 1 t 2 tablets per day, orally.

Cobolmin Dose for Pernicious Anemia:

• 2 tablets per day.

Cobolmin Dose for Neuropathy or Nerve Disorders:

• In cases of peripheral neuropathy or other nerve disorders, the dosage can vary widely.
• It’s important to follow the specific recommendations of your healthcare provider.
• 3 – 6 tablets per day or more.

Cobolmin Dose for Cognitive Function Support:

• 2 tablets per day, to support cognitive function.

Cobolmin contains Mecobalamin and it is a coenzyme form of vitamin B12, which means it assists in a wide range of biochemical reactions in the body. One of its primary roles is in methylation reactions. Methylation is a process in which a methyl group (CH3) is transferred from one molecule to another. This is critical for the synthesis of DNA, RNA, and various neurotransmitters.