Buscopan Plus tablet is primarily used to relieve abdominal pain, cramps, and discomfort associated with certain conditions:
- Abdominal Pain and Spasms: Buscopan Plus tablets may be used for the relief of abdominal pain and spasms caused by other conditions, such as gastrointestinal disorders or functional abdominal pain.
- Irritable Bowel Syndrome (IBS): Buscopan Plus tablets can be used to alleviate abdominal pain and cramps in individuals with irritable bowel syndrome, a chronic gastrointestinal disorder characterized by abdominal discomfort and altered bowel habits.
- Menstrual Cramps (Dysmenorrhea): Using Buscopan Plus tablets can help relieve the pain and cramping associated with menstrual periods, known as dysmenorrhea.
Off-label Uses of Buscopan Plus Tablet
- Musculoskeletal Pain: Buscopan Plus tablets might be used off-label for the management of musculoskeletal pain conditions, such as back pain, neck pain, or muscular strains.
- Postoperative Pain: Buscopan Plus tablets can be used for the relief of postoperative pain, particularly after abdominal or pelvic surgeries.
- Biliary Colic: Buscopan Plus tablets may be used for the relief of biliary colic, a type of abdominal pain caused by gallbladder contractions and obstruction of the bile ducts.
- Renal Colic: Buscopan Plus tablets may also be used for the relief of renal colic, which refers to severe pain caused by the passage of kidney stones.
What is Buscopan Plus?
Buscopan Plus is a drug that combines Hyoscine Butylbromide and Paracetamol, manufactured and marketed by Boehringer-Ingelheim.
Buscopan Plus : Available Formulations and Strengths
Presently, Buscopan is available in Tablets and Injection Forms
Buscopan Plus Tablet : Hyoscine Butylbromide 10mg and Paracetamol 500mg strengths
Buscopan Tablet : Hyoscine Butylbromide 10mg strength
Buscopan Injection : Hyoscine Butylbromide 4mg/ml strength
Who Should Not Use Buscopan Plus?
There are some important contraindications that should be considered before using the Buscopan Plus tablet.
- Hypersensitivity: Buscopan Plus should not be used in individuals who have a known hypersensitivity or allergy to hyoscine butylbromide, paracetamol, or any other ingredients present in the medication.
- Glaucoma: Buscopan Plus is contraindicated in individuals with closed-angle glaucoma, a type of glaucoma where the drainage angle of the eye becomes blocked.
- Urinary Retention: Buscopan Plus is contraindicated in individuals with urinary retention, a condition where there is an inability to fully empty the bladder.
- Obstructive Gastrointestinal Conditions: Buscopan Plus should not be used in individuals with conditions that may cause a blockage or obstruction in the gastrointestinal tract, such as paralytic ileus or pyloric stenosis.
- Severe Ulcerative Colitis: Buscopan Plus is contraindicated in individuals with severe ulcerative colitis, a chronic inflammatory bowel disease affecting the colon and rectum.
- Severe Hepatic Impairment: Buscopan Plus should not be used in individuals with severe liver disease or impaired liver function.
- Porphyria: Buscopan Plus is contraindicated in individuals with a history of porphyria, a group of rare genetic disorders that affect the production of heme, a component of hemoglobin.
What is the Recommended Daily Dosage of Buscopan Plus?
Buscopan Plus Dose for Abdominal Pain or Discomfort: 1-2 tablets four times a day.
Buscopan Plus Dose for Irritable Bowel Syndrome (IBS): 1 tablet three times a day. The dosage can be adjusted based on individual response and tolerability.
Buscopan Plus Dose for Other Conditions (Gastrointestinal Spasms): 1-2 tablets four times a day.
How Buscopan Plus Works?
Buscopan Plus mode of action depending on each ingredient works in its own way to provide relief from pain and discomfort.
- Hyoscine butylbromide is an antispasmodic agent that acts on the smooth muscles of the gastrointestinal tract. It works by blocking the action of acetylcholine, a neurotransmitter responsible for muscle contractions. By inhibiting the activity of acetylcholine, hyoscine butylbromide helps to relax and reduce the spasms of the smooth muscles in the gastrointestinal tract.
- Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). Its exact mode of action is not fully understood, but it is believed to work by inhibiting the production of certain chemicals called prostaglandins in the central nervous system. Prostaglandins are substances that contribute to pain and inflammation.
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