Actim Tablet Uses

Actim tablet belongs to a class of drugs known as beta-blockers that is used for the treatment of various cardiovascular conditions, including:

1. Hypertension (High Blood Pressure): Actim is commonly used to lower blood pressure in individuals with hypertension. By blocking the effects of certain hormones like adrenaline on the heart and blood vessels, Actim helps relax and widen blood vessels, reducing the workload on the heart and lowering blood pressure.
2. Heart Failure: Actim is also used in the management of chronic heart failure. It can help improve the heart’s pumping ability, decrease the symptoms of heart failure, and reduce the risk of hospitalization and mortality associated with this condition.
3. Angina Pectoris: The use of Actim is effective in relieving symptoms of angina, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By reducing heart rate and decreasing the workload on the heart, Actim helps to alleviate angina symptoms and improve exercise tolerance.
4. Certain Arrhythmias: Actim may be used to treat certain types of arrhythmias, such as atrial fibrillation or ventricular tachycardia. It helps regulate the heart’s rhythm and reduce the risk of abnormal heart rhythms.

Off-label Uses of Actim Tablet

1. Migraine Prevention: Actim may be used off-label for the prevention of migraines, particularly in individuals who also have hypertension or cardiovascular risk factors. Actim’s ability to reduce blood pressure and regulate blood flow may help in reducing the frequency and severity of migraines.
2. Performance Anxiety: Actim may be used off-label to manage performance anxiety or stage fright. By blocking the effects of adrenaline on the body, Actim can help reduce physical symptoms of anxiety, such as rapid heart rate and trembling.
3. Thyrotoxicosis: Actim may be used off-label as an adjunctive treatment for thyrotoxicosis, a condition characterized by excessive thyroid hormone production. Actim can help manage symptoms associated with increased heart rate and anxiety in individuals with thyrotoxicosis.
4. Tachycardia: Actim may be used off-label to manage certain types of tachycardia, such as supraventricular tachycardia (SVT). By reducing heart rate and the electrical activity of the heart, Actim can help restore a normal heart rhythm.

Actim is one of the leading brands of Bisoprolol Fumarate, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

The following are some alternative brands of Actim and their manufacturers.

• Concor : Martin Dow Pharmaceuticals Ltd, Pakistan.
• Barilol : Barrett Hodgson Pakistan (Pvt) Ltd, Pakistan.
• Probase : Mass Pharma (Pvt) Ltd, Pakistan.
• Bisoproslol : Atco Laboratories (Pvt) Ltd, Pakistan.
• Monitor : Werrick Pharmaceuticals, Pakistan.
• Corbis : Efroze Chemical Industries (Pvt) Ltd, Pakistan.
• Bisocure : Don Valley Pharma, Pakistan.
• Monocor : Standpharm Pakistan (Pvt) Ltd.
• Safcor : Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.
• Valvozid : Pacific Pharmaceuticals Ltd, Pakistan.

Presently, Actim is available in Tablet Form with the following strengths.

Actim Tablets : 2.5mg, 5mg, and 10mg strengths.

Actim has certain contraindications, which are medical conditions or situations where the use of Actim is not recommended due to potential risks or adverse effects.

Hypersensitivity: Actim should not be used in individuals who have a known hypersensitivity or allergic reaction to Actim or other beta-blockers. Allergic reactions to beta-blockers can range from mild symptoms such as rash and itching to severe reactions, including difficulty breathing or anaphylaxis.

Severe Bradycardia: Actim is contraindicated in individuals with bradycardia, a slow heart rate, especially if it is associated with symptoms such as dizziness, lightheadedness, or fainting. Actim can further slow the heart rate and worsen these symptoms.

Heart Block: Actim should not be used in individuals with second or third-degree heart block, a condition where the electrical signals in the heart are impaired. Actim can further delay or block these signals and worsen heart block.

Cardiogenic Shock: Actim is contraindicated in individuals with cardiogenic shock, a condition where the heart is unable to pump enough blood to meet the body’s needs. Actim can further reduce heart function and worsen the condition.

Decompensated Heart Failure: Actim should not be used in individuals with decompensated heart failure, a severe form of heart failure where the symptoms are not adequately controlled. Actim can worsen heart failure symptoms and lead to fluid retention and shortness of breath.

Severe Asthma or Chronic Obstructive Pulmonary Disease (COPD): Actim is generally contraindicated in individuals with severe asthma or COPD because it can cause bronchospasm and worsen breathing difficulties.

Actim Dose for Hypertension (High Blood Pressure):

• Starting Dose: One Tablet of 5mg once daily.
• The dose may be increased gradually to achieve the desired blood pressure reduction, typically up to a maximum of 10mg tablet once daily.

Actim Dose for Heart Failure:

• Starting Dose: A Half Tablet of 2.5mg once daily.
• The dose may be gradually increased over time, guided by the healthcare professional, to a target maintenance dose of 10mg tablet once daily.

Actim is a selective beta-1 adrenergic receptor blocker, also known as a beta-blocker. Its mode of action involves blocking the effects of certain hormones, specifically adrenaline (epinephrine) and noradrenaline (norepinephrine), on the beta-1 adrenergic receptors in the body.