Elezo Side Effects

Elezo is an iron supplement used to treat or prevent iron deficiency anemia. Like any medication or supplement, Elezo can have various side effects, some of which are more common than others. It’s important to note that not everyone experiences these side effects, and their severity can vary from person to person health conditions. Some common and less common side effects of Elezo may include.

Common Side Effects

• Gastrointestinal Distress: The most common side effects are related to the gastrointestinal tract. These can include constipation, diarrhea, nausea, vomiting, or stomach upset. Some people may also experience abdominal pain or discomfort.
• Darkening of Stools: Elezo can cause stools to turn black, which is a harmless effect of the iron reacting in the digestive system.
• Tooth Discoloration: In some cases, Elezo may cause a darkening of the teeth, especially if the liquid form is used and not properly diluted or rinsed from the mouth.
• Allergic Reactions: While rare, allergic reactions to Polysaccharide Iron Complex can occur. Symptoms might include itching, rash, swelling, dizziness, or difficulty breathing. Seek immediate medical attention if any signs of an allergic reaction appear.
• Staining or Discoloration: Liquid forms of Elezo might cause temporary staining or discoloration of teeth or oral tissues. Properly diluting and rinsing the mouth after taking the supplement can minimize this risk.

Less Common Side Effects

• Severe Gastrointestinal Issues: Some individuals might experience more severe gastrointestinal problems, such as persistent abdominal pain, severe diarrhea, or persistent nausea and vomiting. These symptoms should be reported to a healthcare professional immediately.
• Allergic Reactions: While mentioned earlier as a less common side effect, severe allergic reactions, though rare, can occur. Symptoms might include hives, swelling of the face, lips, tongue, or throat, difficulty breathing, or a rapid heartbeat. Anaphylaxis, a severe and potentially life-threatening allergic reaction, is extremely rare but requires immediate emergency medical attention.
• Iron Overload: Prolonged use of Elezo can lead to iron overload in the body, especially in individuals with certain conditions like hemochromatosis or those who don’t need supplemental iron. Iron overload can cause symptoms such as joint pain, fatigue, abdominal pain, and in severe cases, organ damage. Monitoring by a healthcare provider is essential to prevent this complication.
• Skin Reactions: Some individuals might experience skin reactions like itching, rashes, or redness after taking Elezo. These reactions can range from mild to severe.
• Low Blood Pressure: In rare cases, Elezo might cause a drop in blood pressure, leading to symptoms like dizziness, lightheadedness, or fainting.

Elezo is one of the leading brands of Polysaccharide Iron Complex, manufactured and marketed by Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

Presently, Elezo is available in Capsule and Syrup Forms with the following strengths.

Elezo Capsule : 150mg strength.

Elezo Syrup : 100mg/5ml strength.

1. Antacids and Proton Pump Inhibitors (PPIs): These medications used to treat heartburn or stomach ulcers can decrease the absorption of Elezo, including PIC. It’s advisable to take Elezo at least 2 hours before or after taking antacids or PPIs to avoid interference with iron absorption.
2. Tetracycline Antibiotics: Elezo can bind to tetracycline antibiotics in the stomach, reducing the absorption of both medications. To prevent this interaction, it’s recommended to take tetracycline antibiotics at least 2 hours before or after taking PIC.
3. Levothyroxine (thyroid medication): Elezo can interfere with the absorption of levothyroxine, reducing its effectiveness. To avoid this interaction, take levothyroxine at least 4 hours before or after taking iron supplements.
4. Quinolone Antibiotics: Similar to tetracyclines, quinolone antibiotics (e.g., ciprofloxacin) can bind to Elezo, reducing their absorption. Take quinolone antibiotics at least 2 hours before or after PIC to minimize this interaction.
5. Methyldopa (used for high blood pressure during pregnancy):  Elezo might decrease the absorption of methyldopa. If you’re taking both medications, consult your healthcare provider to ensure proper management and potential dosage adjustments.
6. Bisphosphonates and Thyroid Hormones:  Elezo can potentially interfere with the absorption of these medications. It’s advisable to take them at least 2 hours before or after taking PIC.
7. Parkinson’s Disease Medications (e.g., Levodopa):  Elezo can decrease the absorption of levodopa, a medication used in Parkinson’s disease. To minimize this interaction, take levodopa at least 2 hours before or after Elezo.