Myfol Tablet Uses

Myfol tablet is used to treat or prevent folate deficiency in various health conditions such as pregnancy, heart disease, cognitive decline, and arthritis. It is a synthetic form of folate (vitamin B9) that is critical in many key metabolic processes. Myfol tablet synthesizes DNA and RNA, producing neurotransmitters, cell growth and division, and other vital functions. Following are some common (approved) and off-label (clinical trial by health professionals) uses of Myfol tablets:

Common Uses of Myfol Tablet

1. Folate Deficiency: Myfol tablet is used to treat or prevent folate deficiency, which can occur due to inadequate dietary intake, malabsorption conditions, or increased folate requirements during certain medical conditions.
2. Depression: Myfol tablet is sometimes used as an adjunctive treatment in major depressive disorder, particularly in cases where there is evidence of folate deficiency or poor response to conventional antidepressant medications. It is thought to help support the neurotransmitters’ production in mood regulation.
3. Antidepressant-Associated Sexual Dysfunction: Myfol tablets may be used to mitigate sexual dysfunction side effects caused by certain antidepressant medications, particularly selective serotonin reuptake inhibitors (SSRIs).
4. Cognitive Function: Myfol tablet has a potential role in improving cognitive function and reducing cognitive decline associated with aging and neurological conditions.
5. Use During Pregnancy: Myfol tablets may be beneficial for pregnant women who are at risk for delivering a child with neural tube defects due to inadequate folate intake during pregnancy.

Off-label Uses of Myfol Tablet

1. Treatment-Resistant Depression: Myfol tablets may be used off-label as an adjunctive treatment in individuals with treatment-resistant depression who have not adequately responded to other antidepressant medications.
2. Bipolar Disorder: Myfol tablets may be used as an adjunctive treatment for bipolar disorder, particularly in cases where there is evidence of folate deficiency or a poor response to standard mood stabilizers.
3. Schizophrenia: Myfol tablets are also can used as an adjunctive treatment in schizophrenia, suggesting that it may help reduce symptoms and improve treatment outcomes.
4. Autism Spectrum Disorders: Myfol tablets may used for the treatment of autism spectrum disorders (ASD), particularly in individuals with genetic variants associated with impaired folate metabolism.
5. Cardiovascular Health: Myfol may be used as a supplement to support cardiovascular health, particularly in individuals with certain genetic variations or medical conditions associated with impaired folate metabolism.

Myfol is one of the leading brands of L-Methylfolate Calcium, manufactured and marketed by RG Pharmaceuticals Pakistan.

Following are some alternative brands of Myfol and their manufacturers.

• Maxfol : High-Q International.
• Locyst : RG Pharmaceutica (Pvt) Ltd, Pakistan.
• Adfolic : Pharmevo Pakistan (Pvt) Ltd.
• Folifort : Indus Pharmaceuticals, Pakistan.
• Mom Folic : Atco Laboratories Ltd, Pakistan.
• Novafol : AGP Pharma (Pvt) Ltd, Pakistan.
• Q Folic : Highnoon Laboratories, Pakistan.
• Neevo : Hiranis Pharmaceuticals, Pakistan.
• Keplin : Genetics Pharmaceuticals, Pakistan.
• Biofol : Biolex Phrama.
• Mytol F Sachet : Nexcon Pharma.

Presently, Myfol is available in Tablet Form

Myfol Tablets : 400mcg Strength

Despite the potential benefits of Myfol uses discussed above, there are several contraindications that must be taken into consideration before beginning a course of treatment:

Allergy or Hypersensitivity: Myfol should not be used in individuals who have a known allergy or hypersensitivity to Myfol or any of its components.

Vitamin B12 Deficiency: Myfol should be used with caution in individuals with vitamin B12 deficiency. Myfol supplementation without addressing underlying vitamin B12 deficiency may mask or worsen neurological symptoms associated with vitamin B12 deficiency.

Methylmalonic Acidemia: Myfol is contraindicated in individuals with methylmalonic acidemia, a rare inherited disorder that affects the body’s ability to process certain proteins and fats.

Leber’s Hereditary Optic Neuropathy (LHON): LHON is a genetic condition that primarily affects the eyes, leading to vision loss. Myfol should not be used in individuals with LHON, as it may potentially worsen the condition.

Kidney or Liver Disease: People who suffer from certain medical conditions such as kidney disease or liver disease should avoid taking this supplement as it could worsen their condition.

Drug Interactions: People with low vitamin B12 levels, those taking certain medication for cancer or diabetes, and those with Parkinson’s Disease may also need to avoid Myfol tablets altogether due to possible interactions with other drugs they may be taking at the same time.

The recommended daily allowance (RDA) for adults 19 years or older is 400 micrograms per day.

However, During Pregnant or lactation then the Myfol dose should be increased up to 500 micrograms per day.

Myfol is a biologically active form of vitamin B9 (folate). When ingested orally, it is absorbed through the intestine into the bloodstream where it travels throughout the body and binds with receptor proteins on cells which allow them to recognize and use its active component – methyl tetrahydrofolate (MTHF).

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Myfol Side Effects